PTCT vs XENE

Comparison between PTC Therapeutics Inc (PTCT, Company) and Xenon Pharmaceuticals Inc (XENE, Company).

Both PTCT and XENE are from the Healthcare sector.

5-Year PerformanceXENE has outperformed PTCT, delivering a return of +29.9% compared to +12.7%

PTCT vs XENE - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PTCT(COMPANY)	XENE(COMPANY)
Market Cap	$6.53B	$6.54B
Max Drawdown	94.60%	90.43%
Sharpe Ratio	1.27	1.44
5Y Beta	0.99	0.92
Industry	Biotechnology	Biotechnology
P/E Ratio	-34.15	-14.55
Forward P/E	58.82	N/A
PEG Ratio	0.81	-0.36
5Y EPS CAGR	-16.59%	40.27%
Debt to Equity	-159.00%	0.00%
Free Cash Flow Yield	-3.46%	-4.70%
P/S Ratio	7.83	727.44
P/B Ratio	1743.27	4.89

Market Cap

PTCT

$6.53B

Winner

XENE

$6.54B

Max Drawdown

PTCT

94.60%

Winner

XENE

90.43%

Sharpe Ratio

PTCT

1.27

Winner

XENE

1.44

5Y Beta

PTCT

0.99

Winner

XENE

0.92

Industry

PTCT

Biotechnology

XENE

Biotechnology

P/E Ratio

Winner

PTCT

-34.15

XENE

-14.55

Forward P/E

PTCT

58.82

XENE

N/A

PEG Ratio

PTCT

0.81

Winner

XENE

-0.36

5Y EPS CAGR

PTCT

-16.59%

Winner

XENE

40.27%

Debt to Equity

Winner

PTCT

-159.00%

XENE

0.00%

Free Cash Flow Yield

Winner

PTCT

-3.46%

XENE

-4.70%

P/S Ratio

Winner

PTCT

7.83

XENE

727.44

P/B Ratio

PTCT

1743.27

Winner

XENE

4.89

PTCT vs XENE - Historical Returns

Returns include dividend reinvestment.

Period	PTCT	XENE
1 month	+7.17%	+28.83%
3 months	+9.51%	+14.63%
6 months	+8.33%	+67.53%
1 year	+63.11%	+111.83%
5 years(CAGR)	+12.71%	+29.95%
10 years(CAGR)	+27.07%	+24.13%
Max(CAGR)	+12.68%	+17.17%

PTCT

+7.17%

Winner

XENE

+28.83%

PTCT

+9.51%

Winner

XENE

+14.63%

PTCT

+8.33%

Winner

XENE

+67.53%

PTCT

+63.11%

Winner

XENE

+111.83%

5Y(CAGR)

PTCT

+12.71%

Winner

XENE

+29.95%

10Y(CAGR)

Winner

PTCT

+27.07%

XENE

+24.13%

Max(CAGR)

PTCT

+12.68%

Winner

XENE

+17.17%

PTCT vs XENE - Annual Returns (2013 - 2026)

Returns include dividend reinvestment.

Year	PTCT	XENE
2026	+2.32%	+50.55%
2025	+65.56%	+11.58%
2024	+60.98%	-12.71%
2023	-27.78%	+23.62%
2022	-10.36%	+24.82%
2021	-34.17%	+111.94%
2020	+25.99%	+12.10%
2019	+42.90%	+96.26%
2018	+96.56%	+119.48%
2017	+48.53%	-64.01%
2016	-64.65%	-3.27%
2015	-36.47%	-57.01%
2014	+209.26%	+88.10%
2013	+2.91%	N/A

PTCT vs XENE Drawdown Comparison

The maximum drawdown for PTCT was -94.60%, occurring on Nov 3, 2016. Recovery took 2689 trading sessions.

The maximum drawdown for XENE was -90.43%, occurring on Nov 14, 2017. Recovery took 1696 trading sessions.

The current PTCT drawdown is -12.32%. The current XENE drawdown is -5.61%.

Rank	PTCT	XENE
#1	-94.60% Mar 17, 2015 - Nov 21, 2025	-90.43% Jan 8, 2015 - Oct 4, 2021
#2	-56.81% Feb 27, 2014 - Sep 15, 2014	-43.59% Feb 9, 2024 - Mar 9, 2026
#3	-39.55% Sep 23, 2013 - Jan 15, 2014	-34.08% May 9, 2023 - Dec 22, 2023
#4	-27.17% Nov 26, 2025 - Jul 7, 2026	-30.14% Nov 5, 2021 - Aug 4, 2022
#5	-25.36% Sep 26, 2014 - Dec 2, 2014	-25.87% Nov 11, 2014 - Dec 11, 2014
#6	-25.27% Jan 17, 2014 - Feb 20, 2014	-18.40% Mar 9, 2026 - Jul 7, 2026
#7	-23.59% Jul 18, 2013 - Sep 4, 2013	-17.08% Mar 1, 2023 - May 3, 2023
#8	-22.29% Jun 25, 2013 - Jul 17, 2013	-16.98% Aug 24, 2022 - Feb 13, 2023
#9	-19.59% Jan 20, 2015 - Feb 23, 2015	-11.44% Oct 15, 2021 - Nov 2, 2021
#10	-18.21% Sep 10, 2013 - Sep 23, 2013	-11.09% Dec 11, 2014 - Dec 29, 2014
#11	-13.33% Dec 12, 2014 - Dec 19, 2014	-9.36% Feb 13, 2023 - Mar 1, 2023
#12	-12.83% Jul 9, 2026 - Jul 14, 2026	-8.58% Jan 8, 2024 - Feb 8, 2024
#13	-10.21% Dec 19, 2014 - Jan 13, 2015	-8.27% Aug 10, 2022 - Aug 24, 2022
#14	-6.13% Feb 25, 2015 - Mar 11, 2015	-6.08% Dec 29, 2014 - Jan 7, 2015
#15	-3.04% Dec 9, 2014 - Dec 11, 2014	-5.61% Jul 9, 2026 - Jul 16, 2026