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PRTA vs SPY

Comparison between Prothena Corporation plc (PRTA, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).

5-Year PerformanceSPY has outperformed PRTA, delivering a return of +13.3% compared to -21.0%

PRTA vs SPY - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap / Net Assets
PRTA
$532M
Winner
SPY
$735B
Expense Ratio
PRTA
N/A
SPY
0.09%
Max Drawdown
PRTA
94.19%
Winner
SPY
56.47%
Sharpe Ratio
PRTA
1.36
Winner
SPY
1.62
5Y Beta
Winner
PRTA
0.93
SPY
1.00
Industry
PRTA
Biotechnology
SPY
N/A
P/E Ratio
Winner
PRTA
-3.58
SPY
28.99
Forward P/E
Winner
PRTA
10.63
SPY
22.37
PEG Ratio
PRTA
-0.10
SPY
N/A
5Y Dividends CAGR
PRTA
N/A
SPY
5.43%
5Y EPS CAGR
PRTA
-1.54%
Winner
SPY
26.05%
Debt to Equity
Winner
PRTA
0.00%
SPY
32.40%
Free Cash Flow Yield
PRTA
-15.28%
SPY
N/A
P/S Ratio
PRTA
9.06
Winner
SPY
3.74
P/B Ratio
Winner
PRTA
1.69
SPY
5.61

PRTA vs SPY - Historical Returns

Returns include dividend reinvestment.

1M
PRTA
-21.45%
Winner
SPY
+1.90%
3M
PRTA
-7.08%
Winner
SPY
+8.55%
6M
PRTA
-20.60%
Winner
SPY
+8.18%
1Y
Winner
PRTA
+73.72%
SPY
+25.79%
5Y(CAGR)
PRTA
-21.04%
Winner
SPY
+13.32%
10Y(CAGR)
PRTA
-16.03%
Winner
SPY
+15.19%
Max(CAGR)
PRTA
+1.49%
Winner
SPY
+8.47%

PRTA vs SPY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

YearPRTASPY
2026-4.46%+8.26%
2025-30.14%+18.00%
2024-64.06%+25.59%
2023-32.07%+26.72%
2022+22.41%-18.64%
2021+301.63%+30.52%
2020-23.16%+17.28%
2019+50.76%+31.09%
2018-72.75%-5.24%
2017-24.70%+20.78%
2016-20.94%+13.59%
2015+234.69%+1.31%
2014-26.12%+14.56%
2013+278.86%+29.00%
2012+1.81%+14.17%
2011N/A+0.85%
2010N/A+13.14%
2009N/A+22.67%
2008N/A-36.25%
2007N/A+5.32%
2006N/A+13.85%
2005N/A+5.32%
2004N/A+10.75%
2003N/A+24.18%
2002N/A-22.42%
2001N/A-10.13%
2000N/A-8.84%
1999N/A+8.61%

PRTA vs SPY Drawdown Comparison

The maximum drawdown for PRTA was -94.19%, occurring on May 27, 2025. This drawdown has not yet recovered.

The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.

The current PRTA drawdown is -88.86%. The current SPY drawdown is -2.90%.

RankPRTASPY
#1-94.19%
Sep 23, 2021 - May 27, 2025
-55.20%
Oct 9, 2007 - Aug 16, 2012
#2-90.85%
Nov 27, 2015 - Sep 10, 2021
-47.50%
Mar 24, 2000 - Oct 26, 2006
#3-64.27%
Mar 20, 2014 - Jun 17, 2015
-33.70%
Feb 19, 2020 - Aug 10, 2020
#4-36.96%
Jul 28, 2015 - Nov 18, 2015
-24.50%
Jan 3, 2022 - Dec 13, 2023
#5-20.33%
Dec 31, 2012 - Apr 9, 2013
-19.34%
Sep 20, 2018 - Apr 12, 2019
#6-18.45%
Jun 20, 2013 - Jul 12, 2013
-18.76%
Feb 19, 2025 - Jun 26, 2025
#7-17.61%
Jan 30, 2014 - Feb 25, 2014
-13.02%
Jul 20, 2015 - Apr 18, 2016
#8-15.12%
Dec 16, 2013 - Jan 29, 2014
-10.10%
Jan 26, 2018 - Aug 6, 2018
#9-14.72%
Oct 2, 2013 - Oct 25, 2013
-9.44%
Sep 2, 2020 - Nov 11, 2020
#10-11.68%
May 28, 2013 - Jun 7, 2013
-9.30%
Jan 19, 2000 - Mar 17, 2000
#11-10.76%
Aug 2, 2013 - Aug 22, 2013
-9.05%
Jul 19, 2007 - Oct 5, 2007
#12-10.14%
Jun 22, 2015 - Jul 14, 2015
-8.88%
Jan 27, 2026 - Apr 14, 2026
#13-7.65%
Mar 12, 2014 - Mar 19, 2014
-8.41%
Jul 16, 2024 - Sep 19, 2024
#14-6.94%
Aug 29, 2013 - Oct 2, 2013
-7.35%
Sep 14, 2012 - Jan 2, 2013
#15-6.73%
Jul 22, 2015 - Jul 28, 2015
-7.27%
Sep 18, 2014 - Oct 31, 2014

Correlation

Correlation between PRTA and SPY is -0.21 which considered as a very weak or no correlation - the stocks move independently of each other.

-0.21
-101

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