PRTA vs NPFD

Comparison between Prothena Corporation plc (PRTA, Company) and Nuveen Variable Rate Preferred & Income Fund (NPFD, Company).

PRTA is from the Healthcare sector, while NPFD is from the Financial Services sector.

5-Year PerformanceNPFD has outperformed PRTA, delivering a return of +1.9% compared to -30.3%

PRTA vs NPFD - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PRTA(COMPANY)	NPFD(COMPANY)
Market Cap	$448M	$447M
Max Drawdown	94.19%	45.11%
Sharpe Ratio	0.77	0.44
5Y Beta	0.90	0.32
Industry	Biotechnology	Asset Management
P/E Ratio	-3.01	5.13
Forward P/E	10.63	N/A
PEG Ratio	-0.08	34.58
Dividend Yield	N/A	10.70%
5Y EPS CAGR	-1.54%	N/A
Debt to Equity	0.00%	38.62%
Free Cash Flow Yield	-18.16%	17.56%

Market Cap

Winner

PRTA

$448M

NPFD

$447M

Max Drawdown

PRTA

94.19%

Winner

NPFD

45.11%

Sharpe Ratio

Winner

PRTA

0.77

NPFD

0.44

5Y Beta

PRTA

0.90

Winner

NPFD

0.32

Industry

PRTA

Biotechnology

NPFD

Asset Management

P/E Ratio

Winner

PRTA

-3.01

NPFD

5.13

Forward P/E

PRTA

10.63

NPFD

N/A

PEG Ratio

Winner

PRTA

-0.08

NPFD

34.58

Dividend Yield

PRTA

N/A

NPFD

10.70%

5Y EPS CAGR

PRTA

-1.54%

NPFD

N/A

Debt to Equity

Winner

PRTA

0.00%

NPFD

38.62%

Free Cash Flow Yield

PRTA

-18.16%

Winner

NPFD

17.56%

PRTA vs NPFD - Historical Returns

Returns include dividend reinvestment.

Period	PRTA	NPFD
1 month	-10.68%	+0.07%
3 months	-20.50%	-1.04%
6 months	-14.70%	-0.33%
1 year	+26.18%	+6.69%
5 years(CAGR)	-30.33%	+1.94%
10 years(CAGR)	-16.72%	N/A
Max(CAGR)	+1.26%	+1.94%

PRTA

-10.68%

Winner

NPFD

+0.07%

PRTA

-20.50%

Winner

NPFD

-1.04%

PRTA

-14.70%

Winner

NPFD

-0.33%

Winner

PRTA

+26.18%

NPFD

+6.69%

5Y(CAGR)

PRTA

-30.33%

Winner

NPFD

+1.94%

10Y(CAGR)

PRTA

-16.72%

NPFD

N/A

Max(CAGR)

PRTA

+1.26%

Winner

NPFD

+1.94%

PRTA vs NPFD - Annual Returns (2012 - 2026)

Returns include dividend reinvestment.

Year	PRTA	NPFD
2026	-7.28%	+1.85%
2025	-30.14%	+14.63%
2024	-64.06%	+22.72%
2023	-32.07%	-2.09%
2022	+22.41%	-25.24%
2021	+301.63%	+1.40%
2020	-23.16%	N/A
2019	+50.76%	N/A
2018	-72.75%	N/A
2017	-24.70%	N/A
2016	-20.94%	N/A
2015	+234.69%	N/A
2014	-26.12%	N/A
2013	+278.86%	N/A
2012	+1.81%	N/A

PRTA vs NPFD Drawdown Comparison

The maximum drawdown for PRTA was -94.19%, occurring on May 27, 2025. This drawdown has not yet recovered.

The maximum drawdown for NPFD was -39.16%, occurring on May 12, 2023. Recovery took 905 trading sessions.

The current PRTA drawdown is -89.19%. The current NPFD drawdown is -3.47%.

Rank	PRTA	NPFD
#1	-94.19% Sep 23, 2021 - May 27, 2025	-39.16% Jan 13, 2022 - Aug 25, 2025
#2	-90.85% Nov 27, 2015 - Sep 10, 2021	-9.89% Feb 19, 2026 - Mar 30, 2026
#3	-64.27% Mar 20, 2014 - Jun 17, 2015	-3.39% Oct 20, 2025 - Feb 2, 2026
#4	-36.96% Jul 28, 2015 - Nov 18, 2015	-2.00% Sep 24, 2025 - Oct 15, 2025
#5	-20.33% Dec 31, 2012 - Apr 9, 2013	-0.76% Feb 11, 2026 - Feb 17, 2026
#6	-18.45% Jun 20, 2013 - Jul 12, 2013	-0.63% Dec 31, 2021 - Jan 6, 2022
#7	-17.61% Jan 30, 2014 - Feb 25, 2014	-0.51% Sep 2, 2025 - Sep 15, 2025
#8	-15.12% Dec 16, 2013 - Jan 29, 2014	-0.46% Feb 5, 2026 - Feb 11, 2026
#9	-14.72% Oct 2, 2013 - Oct 25, 2013	-0.40% Oct 15, 2025 - Oct 20, 2025
#10	-11.68% May 28, 2013 - Jun 7, 2013	-0.39% Jan 6, 2022 - Jan 10, 2022
#11	-10.76% Aug 2, 2013 - Aug 22, 2013	-0.28% Dec 23, 2021 - Dec 30, 2021
#12	-10.14% Jun 22, 2015 - Jul 14, 2015	-0.20% Aug 26, 2025 - Aug 29, 2025
#13	-7.65% Mar 12, 2014 - Mar 19, 2014	-0.15% Sep 18, 2025 - Sep 22, 2025
#14	-6.94% Aug 29, 2013 - Oct 2, 2013	-0.04% Dec 17, 2021 - Dec 21, 2021
#15	-6.73% Jul 22, 2015 - Jul 28, 2015	-0.04% Dec 21, 2021 - Dec 23, 2021