PRTA vs CABA

Comparison between Prothena Corporation plc (PRTA, Company) and Cabaletta Bio Inc (CABA, Company).

Both PRTA and CABA are from the Healthcare sector.

5-Year PerformanceCABA has outperformed PRTA, delivering a return of -17.6% compared to -29.4%

PRTA vs CABA - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PRTA(COMPANY)	CABA(COMPANY)
Market Cap	$474M	$475M
Max Drawdown	94.19%	96.63%
Sharpe Ratio	1.09	0.85
5Y Beta	0.94	1.68
Industry	Biotechnology	Biotechnology
P/E Ratio	-3.19	-2.06
Forward P/E	10.63	N/A
PEG Ratio	-0.09	N/A
5Y EPS CAGR	-1.54%	8.20%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-17.16%	-30.17%

Market Cap

PRTA

$474M

Winner

CABA

$475M

Max Drawdown

Winner

PRTA

94.19%

CABA

96.63%

Sharpe Ratio

Winner

PRTA

1.09

CABA

0.85

5Y Beta

Winner

PRTA

0.94

CABA

1.68

Industry

PRTA

Biotechnology

CABA

Biotechnology

P/E Ratio

Winner

PRTA

-3.19

CABA

-2.06

Forward P/E

PRTA

10.63

CABA

N/A

PEG Ratio

PRTA

-0.09

CABA

N/A

5Y EPS CAGR

PRTA

-1.54%

Winner

CABA

8.20%

Debt to Equity

PRTA

0.00%

CABA

0.00%

Free Cash Flow Yield

Winner

PRTA

-17.16%

CABA

-30.17%

PRTA vs CABA - Historical Returns

Returns include dividend reinvestment.

Period	PRTA	CABA
1 month	-6.88%	-13.68%
3 months	+3.96%	-4.38%
6 months	-4.80%	+17.84%
1 year	+55.30%	+64.16%
5 years(CAGR)	-29.43%	-17.59%
10 years(CAGR)	-13.89%	N/A
Max(CAGR)	+1.61%	-17.25%

Winner

PRTA

-6.88%

CABA

-13.68%

Winner

PRTA

+3.96%

CABA

-4.38%

PRTA

-4.80%

Winner

CABA

+17.84%

PRTA

+55.30%

Winner

CABA

+64.16%

5Y(CAGR)

PRTA

-29.43%

Winner

CABA

-17.59%

10Y(CAGR)

PRTA

-13.89%

CABA

N/A

Max(CAGR)

Winner

PRTA

+1.61%

CABA

-17.25%

PRTA vs CABA - Annual Returns (2012 - 2026)

Returns include dividend reinvestment.

Year	PRTA	CABA
2026	-2.93%	+28.51%
2025	-30.14%	-6.01%
2024	-64.06%	-89.76%
2023	-32.07%	+141.49%
2022	+22.41%	+137.18%
2021	+301.63%	-70.57%
2020	-23.16%	-10.22%
2019	+50.76%	+39.70%
2018	-72.75%	N/A
2017	-24.70%	N/A
2016	-20.94%	N/A
2015	+234.69%	N/A
2014	-26.12%	N/A
2013	+278.86%	N/A
2012	+1.81%	N/A

PRTA vs CABA Drawdown Comparison

The maximum drawdown for PRTA was -94.19%, occurring on May 27, 2025. This drawdown has not yet recovered.

The maximum drawdown for CABA was -96.63%, occurring on Sep 23, 2022. Recovery took 964 trading sessions.

The current PRTA drawdown is -88.68%. The current CABA drawdown is -88.81%.

Rank	PRTA	CABA
#1	-94.19% Sep 23, 2021 - May 27, 2025	-96.63% Jan 29, 2020 - Nov 27, 2023
#2	-90.85% Nov 27, 2015 - Sep 10, 2021	-95.90% Feb 8, 2024 - Apr 8, 2025
#3	-64.27% Mar 20, 2014 - Jun 17, 2015	-55.51% Nov 19, 2019 - Jan 29, 2020
#4	-36.96% Jul 28, 2015 - Nov 18, 2015	-26.79% Nov 27, 2023 - Dec 13, 2023
#5	-20.33% Dec 31, 2012 - Apr 9, 2013	-19.64% Jan 8, 2024 - Feb 8, 2024
#6	-18.45% Jun 20, 2013 - Jul 12, 2013	-15.45% Nov 11, 2019 - Nov 15, 2019
#7	-17.61% Jan 30, 2014 - Feb 25, 2014	-6.59% Dec 27, 2023 - Jan 8, 2024
#8	-15.12% Dec 16, 2013 - Jan 29, 2014	-4.83% Dec 19, 2023 - Dec 26, 2023
#9	-14.72% Oct 2, 2013 - Oct 25, 2013	-1.50% Nov 15, 2019 - Nov 19, 2019
#10	-11.68% May 28, 2013 - Jun 7, 2013	-1.41% Oct 30, 2019 - Nov 1, 2019
#11	-10.76% Aug 2, 2013 - Aug 22, 2013	N/A
#12	-10.14% Jun 22, 2015 - Jul 14, 2015	N/A
#13	-7.65% Mar 12, 2014 - Mar 19, 2014	N/A
#14	-6.94% Aug 29, 2013 - Oct 2, 2013	N/A
#15	-6.73% Jul 22, 2015 - Jul 28, 2015	N/A