PRME vs COFS

Comparison between Prime Medicine Inc (PRME, Company) and Choiceone Financial Services Inc (COFS, Company).

PRME is from the Healthcare sector, while COFS is from the Financial Services sector.

PRME vs COFS - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PRME(COMPANY)	COFS(COMPANY)
Market Cap	$489M	$487M
Max Drawdown	94.55%	78.60%
Sharpe Ratio	1.05	0.43
5Y Beta	2.13	0.75
Industry	Biotechnology	Banks - Regional
P/E Ratio	-2.26	8.76
Forward P/E	N/A	7.79
PEG Ratio	N/A	0.06
Dividend Yield	N/A	3.52%
5Y Dividends CAGR	N/A	11.07%
5Y EPS CAGR	N/A	9.98%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-32.43%	6.32%
P/S Ratio	121.34	2.84
P/B Ratio	6.38	1.01

Market Cap

Winner

PRME

$489M

COFS

$487M

Max Drawdown

PRME

94.55%

Winner

COFS

78.60%

Sharpe Ratio

Winner

PRME

1.05

COFS

0.43

5Y Beta

PRME

2.13

Winner

COFS

0.75

Industry

PRME

Biotechnology

COFS

Banks - Regional

P/E Ratio

Winner

PRME

-2.26

COFS

8.76

Forward P/E

PRME

N/A

COFS

7.79

PEG Ratio

PRME

N/A

COFS

0.06

Dividend Yield

PRME

N/A

COFS

3.52%

5Y Dividends CAGR

PRME

N/A

COFS

11.07%

5Y EPS CAGR

PRME

N/A

COFS

9.98%

Debt to Equity

PRME

0.00%

COFS

0.00%

Free Cash Flow Yield

PRME

-32.43%

Winner

COFS

6.32%

P/S Ratio

PRME

121.34

Winner

COFS

2.84

P/B Ratio

PRME

6.38

Winner

COFS

1.01

PRME vs COFS - Historical Returns

Returns include dividend reinvestment.

Period	PRME	COFS
1 month	-15.91%	+5.51%
3 months	-25.60%	+18.75%
6 months	-32.32%	+4.13%
1 year	+90.07%	+14.74%
5 years(CAGR)	N/A	+9.72%
10 years(CAGR)	N/A	+8.03%
Max(CAGR)	-37.48%	+8.02%

PRME

-15.91%

Winner

COFS

+5.51%

PRME

-25.60%

Winner

COFS

+18.75%

PRME

-32.32%

Winner

COFS

+4.13%

Winner

PRME

+90.07%

COFS

+14.74%

5Y(CAGR)

PRME

N/A

COFS

+9.72%

10Y(CAGR)

PRME

N/A

COFS

+8.03%

Max(CAGR)

PRME

-37.48%

Winner

COFS

+8.02%

PRME vs COFS - Annual Returns (2001 - 2026)

Returns include dividend reinvestment.

Year	PRME	COFS
2026	-21.39%	+13.62%
2025	+16.05%	-11.48%
2024	-66.67%	+21.81%
2023	-49.49%	+8.95%
2022	+20.88%	+17.81%
2021	N/A	-5.48%
2020	N/A	+0.43%
2019	N/A	+31.46%
2018	N/A	+13.41%
2017	N/A	+3.20%
2016	N/A	+2.82%
2015	N/A	+6.50%
2014	N/A	+38.72%
2013	N/A	+22.94%
2012	N/A	+22.04%
2011	N/A	+6.64%
2010	N/A	+38.47%
2009	N/A	+16.12%
2008	N/A	-28.78%
2007	N/A	-25.89%
2006	N/A	-4.00%
2005	N/A	-16.81%
2004	N/A	+39.39%
2003	N/A	+24.87%
2002	N/A	+12.71%
2001	N/A	+0.00%

PRME vs COFS Drawdown Comparison

The maximum drawdown for PRME was -94.55%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The maximum drawdown for COFS was -73.96%, occurring on Jan 26, 2009. Recovery took 1560 trading sessions.

The current PRME drawdown is -86.86%. The current COFS drawdown is -8.64%.

Rank	PRME	COFS
#1	-94.55% Nov 1, 2022 - Apr 8, 2025	-73.96% Oct 29, 2004 - Jan 12, 2011
#2	-3.55% Oct 21, 2022 - Oct 25, 2022	-49.04% Feb 14, 2020 - Dec 13, 2023
#3	N/A	-46.43% Jan 12, 2011 - Feb 24, 2014
#4	N/A	-32.06% Dec 5, 2024 - Apr 11, 2025
#5	N/A	-29.43% Dec 26, 2023 - Jul 16, 2024
#6	N/A	-18.66% Jul 16, 2024 - Sep 19, 2024
#7	N/A	-17.68% Oct 11, 2002 - Jan 30, 2003
#8	N/A	-17.49% Jan 30, 2003 - May 8, 2003
#9	N/A	-17.17% Aug 21, 2018 - May 16, 2019
#10	N/A	-13.79% Mar 13, 2002 - May 6, 2002
#11	N/A	-10.87% Aug 13, 2004 - Oct 29, 2004
#12	N/A	-9.79% Jun 29, 2016 - Dec 6, 2016
#13	N/A	-8.89% Jan 11, 2017 - Dec 21, 2017
#14	N/A	-8.69% Sep 19, 2024 - Oct 24, 2024
#15	N/A	-7.95% Nov 17, 2015 - Jun 29, 2016

Correlation

Correlation between PRME and COFS is -0.69 which considered as a moderate negative correlation - the stocks show some tendency to move in opposite directions.

-0.69

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