PRLB vs SION

Comparison between Proto Labs Inc (PRLB, Company) and Sionna Therapeutics Inc (SION, Company).

PRLB is from the Industrials sector, while SION is from the Healthcare sector.

PRLB vs SION - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	PRLB(COMPANY)	SION(COMPANY)
Market Cap	$1.87B	$1.88B
Max Drawdown	91.22%	69.36%
Sharpe Ratio	1.55	1.46
5Y Beta	1.52	0.92
Industry	Metal Fabrication	Biotechnology
P/E Ratio	72.57	-21.73
Forward P/E	32.26	N/A
PEG Ratio	0.93	N/A
5Y EPS CAGR	-6.44%	N/A
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	3.02%	-3.84%
P/S Ratio	3.43	N/A
P/B Ratio	2.74	6.52

Market Cap

PRLB

$1.87B

Winner

SION

$1.88B

Max Drawdown

PRLB

91.22%

Winner

SION

69.36%

Sharpe Ratio

Winner

PRLB

1.55

SION

1.46

5Y Beta

PRLB

1.52

Winner

SION

0.92

Industry

PRLB

Metal Fabrication

SION

Biotechnology

P/E Ratio

PRLB

72.57

Winner

SION

-21.73

Forward P/E

PRLB

32.26

SION

N/A

PEG Ratio

PRLB

0.93

SION

N/A

5Y EPS CAGR

PRLB

-6.44%

SION

N/A

Debt to Equity

PRLB

0.00%

SION

0.00%

Free Cash Flow Yield

Winner

PRLB

3.02%

SION

-3.84%

P/S Ratio

PRLB

3.43

SION

N/A

P/B Ratio

Winner

PRLB

2.74

SION

6.52

PRLB vs SION - Historical Returns

Returns include dividend reinvestment.

Period	PRLB	SION
1 month	-2.36%	+20.59%
3 months	+32.25%	+8.64%
6 months	+48.78%	+12.19%
1 year	+87.58%	+110.78%
5 years(CAGR)	-3.03%	N/A
10 years(CAGR)	+2.93%	N/A
Max(CAGR)	+6.98%	+49.89%

PRLB

-2.36%

Winner

SION

+20.59%

Winner

PRLB

+32.25%

SION

+8.64%

Winner

PRLB

+48.78%

SION

+12.19%

PRLB

+87.58%

Winner

SION

+110.78%

5Y(CAGR)

PRLB

-3.03%

SION

N/A

10Y(CAGR)

PRLB

+2.93%

SION

N/A

Max(CAGR)

PRLB

+6.98%

Winner

SION

+49.89%

PRLB vs SION - Annual Returns (2012 - 2026)

Returns include dividend reinvestment.

Year	PRLB	SION
2026	+48.78%	+12.19%
2025	+30.55%	+64.56%
2024	+2.87%	N/A
2023	+53.99%	N/A
2022	-52.84%	N/A
2021	-65.82%	N/A
2020	+51.54%	N/A
2019	-9.00%	N/A
2018	+8.61%	N/A
2017	+95.08%	N/A
2016	-18.78%	N/A
2015	-5.85%	N/A
2014	-4.17%	N/A
2013	+81.95%	N/A
2012	+35.93%	N/A

PRLB vs SION Drawdown Comparison

The maximum drawdown for PRLB was -91.22%, occurring on Nov 9, 2022. This drawdown has not yet recovered.

The maximum drawdown for SION was -69.36%, occurring on Apr 10, 2025. Recovery took 137 trading sessions.

The current PRLB drawdown is -69.62%. The current SION drawdown is -4.27%.

Rank	PRLB	SION
#1	-91.22% Jan 27, 2021 - Nov 9, 2022	-69.36% Feb 7, 2025 - Aug 26, 2025
#2	-60.84% Sep 14, 2018 - Dec 22, 2020	-27.07% May 11, 2026 - Jun 8, 2026
#3	-49.77% Oct 24, 2013 - Oct 26, 2017	-23.74% Feb 3, 2026 - Apr 15, 2026
#4	-27.76% Aug 1, 2012 - Jan 15, 2013	-19.06% Oct 21, 2025 - Nov 21, 2025
#5	-25.59% May 1, 2012 - Aug 1, 2012	-18.12% Nov 24, 2025 - Feb 3, 2026
#6	-20.25% Dec 23, 2020 - Jan 20, 2021	-17.26% Apr 16, 2026 - May 11, 2026
#7	-15.54% Feb 13, 2013 - May 3, 2013	-15.94% Aug 28, 2025 - Sep 22, 2025
#8	-14.52% Apr 3, 2012 - Apr 27, 2012	-5.53% Oct 3, 2025 - Oct 15, 2025
#9	-13.79% Jun 18, 2018 - Jul 25, 2018	-3.56% Sep 29, 2025 - Oct 3, 2025
#10	-12.87% May 10, 2013 - Jun 17, 2013	-2.41% Oct 16, 2025 - Oct 21, 2025
#11	-11.38% Feb 29, 2012 - Mar 9, 2012	-0.36% Aug 26, 2025 - Aug 28, 2025
#12	-11.15% Oct 4, 2013 - Oct 17, 2013	N/A
#13	-10.89% Jul 25, 2018 - Aug 20, 2018	N/A
#14	-10.75% Jan 18, 2013 - Feb 13, 2013	N/A
#15	-10.25% Mar 20, 2018 - Apr 17, 2018	N/A