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PHIO vs SPY

Comparison between Phio Pharmaceuticals Corp (PHIO, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).

5-Year PerformanceSPY has outperformed PHIO, delivering a return of +13.8% compared to -66.1%

PHIO vs SPY - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap / Net Assets
PHIO
$12M
Winner
SPY
$784B
Expense Ratio
PHIO
N/A
SPY
0.09%
Max Drawdown
PHIO
100.00%
Winner
SPY
56.47%
Sharpe Ratio
PHIO
-0.72
Winner
SPY
1.56
5Y Beta
Winner
PHIO
0.00
SPY
1.00
Industry
PHIO
Biotechnology
SPY
N/A
P/E Ratio
Winner
PHIO
-0.75
SPY
28.29
Forward P/E
Winner
PHIO
0.31
SPY
21.75
PEG Ratio
PHIO
-0.03
SPY
N/A
5Y Dividends CAGR
PHIO
N/A
SPY
5.43%
5Y EPS CAGR
PHIO
N/A
SPY
25.98%
Debt to Equity
Winner
PHIO
0.00%
SPY
30.79%
Free Cash Flow Yield
PHIO
-87.03%
SPY
N/A
P/S Ratio
PHIO
48.01
Winner
SPY
3.79
P/B Ratio
Winner
PHIO
0.77
SPY
5.67

PHIO vs SPY - Historical Returns

Returns include dividend reinvestment.

1M
Winner
PHIO
+2.80%
SPY
+2.12%
3M
PHIO
-12.70%
Winner
SPY
+13.14%
6M
PHIO
+0.92%
Winner
SPY
+11.52%
1Y
PHIO
-55.65%
Winner
SPY
+26.68%
5Y(CAGR)
PHIO
-66.06%
Winner
SPY
+13.75%
10Y(CAGR)
PHIO
-68.85%
Winner
SPY
+15.65%
Max(CAGR)
PHIO
-64.40%
Winner
SPY
+8.56%

PHIO vs SPY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

YearPHIOSPY
2026+0.92%+10.80%
2025-44.74%+18.00%
2024-74.02%+25.59%
2023-83.12%+26.72%
2022-65.87%-18.64%
2021-64.41%+30.52%
2020-74.26%+17.28%
2019-51.11%+31.09%
2018-94.00%-5.24%
2017-22.79%+20.78%
2016-81.23%+13.59%
2015-76.13%+1.31%
2014-44.83%+14.56%
2013+38.10%+29.00%
2012-46.15%+14.17%
2011N/A+0.85%
2010N/A+13.14%
2009N/A+22.67%
2008N/A-36.25%
2007N/A+5.32%
2006N/A+13.85%
2005N/A+5.32%
2004N/A+10.75%
2003N/A+24.18%
2002N/A-22.42%
2001N/A-10.13%
2000N/A-8.84%
1999N/A+8.61%

PHIO vs SPY Drawdown Comparison

The maximum drawdown for PHIO was -100.00%, occurring on Feb 5, 2026. This drawdown has not yet recovered.

The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.

The current PHIO drawdown is -100.00%. The current SPY drawdown is -0.62%.

RankPHIOSPY
#1-100.00%
Mar 14, 2013 - Feb 5, 2026
-55.20%
Oct 9, 2007 - Aug 16, 2012
#2-92.73%
Jul 5, 2012 - Mar 11, 2013
-47.50%
Mar 24, 2000 - Oct 26, 2006
#3-56.25%
May 14, 2012 - Jul 3, 2012
-33.70%
Feb 19, 2020 - Aug 10, 2020
#4-11.11%
Mar 11, 2013 - Mar 13, 2013
-24.50%
Jan 3, 2022 - Dec 13, 2023
#5N/A-19.34%
Sep 20, 2018 - Apr 12, 2019
#6N/A-18.76%
Feb 19, 2025 - Jun 26, 2025
#7N/A-13.02%
Jul 20, 2015 - Apr 18, 2016
#8N/A-10.10%
Jan 26, 2018 - Aug 6, 2018
#9N/A-9.44%
Sep 2, 2020 - Nov 11, 2020
#10N/A-9.30%
Jan 19, 2000 - Mar 17, 2000
#11N/A-9.05%
Jul 19, 2007 - Oct 5, 2007
#12N/A-8.88%
Jan 27, 2026 - Apr 14, 2026
#13N/A-8.41%
Jul 16, 2024 - Sep 19, 2024
#14N/A-7.35%
Sep 14, 2012 - Jan 2, 2013
#15N/A-7.27%
Sep 18, 2014 - Oct 31, 2014

Correlation

Correlation between PHIO and SPY is -0.51 which considered as a moderate negative correlation - the stocks show some tendency to move in opposite directions.

-0.51
-101

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