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OTLK vs SPY

Comparison between Outlook Therapeutics Inc (OTLK, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).

5-Year PerformanceSPY has outperformed OTLK, delivering a return of +12.4% compared to -51.3%

OTLK vs SPY - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap / Net Assets
OTLK
$163M
Winner
SPY
$781B
Expense Ratio
OTLK
N/A
SPY
0.09%
Max Drawdown
OTLK
99.98%
Winner
SPY
56.47%
Sharpe Ratio
OTLK
0.62
Winner
SPY
1.22
5Y Beta
Winner
OTLK
0.95
SPY
1.00
Industry
OTLK
Biotechnology
SPY
N/A
P/E Ratio
Winner
OTLK
-1.41
SPY
28.78
Forward P/E
Winner
OTLK
2.85
SPY
21.25
5Y Dividends CAGR
OTLK
N/A
SPY
6.00%
5Y EPS CAGR
OTLK
-28.21%
Winner
SPY
25.62%
Debt to Equity
Winner
OTLK
0.00%
SPY
31.92%
Free Cash Flow Yield
OTLK
-28.83%
SPY
N/A
P/S Ratio
OTLK
695.79
Winner
SPY
3.76
P/B Ratio
OTLK
38.42
Winner
SPY
5.64

OTLK vs SPY - Historical Returns

Returns include dividend reinvestment.

1M
OTLK
-22.35%
Winner
SPY
+0.63%
3M
Winner
OTLK
+360.09%
SPY
+4.46%
6M
Winner
OTLK
+162.43%
SPY
+7.67%
1Y
OTLK
-36.54%
Winner
SPY
+17.68%
5Y(CAGR)
OTLK
-51.35%
Winner
SPY
+12.42%
10Y(CAGR)
OTLK
-45.00%
Winner
SPY
+14.84%
Max(CAGR)
OTLK
-46.12%
Winner
SPY
+8.44%

OTLK vs SPY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

YearOTLKSPY
2026+100.00%+8.63%
2025-23.30%+18.00%
2024-75.96%+25.59%
2023-62.48%+26.72%
2022-26.03%-18.64%
2021+12.40%+30.52%
2020+48.57%+17.28%
2019-86.59%+31.09%
2018-60.32%-5.24%
2017-60.39%+20.78%
2016-29.51%+13.59%
2015N/A+1.31%
2014N/A+14.56%
2013N/A+29.00%
2012N/A+14.17%
2011N/A+0.85%
2010N/A+13.14%
2009N/A+22.67%
2008N/A-36.25%
2007N/A+5.32%
2006N/A+13.85%
2005N/A+5.32%
2004N/A+10.75%
2003N/A+24.18%
2002N/A-22.42%
2001N/A-10.13%
2000N/A-8.84%
1999N/A+8.61%

OTLK vs SPY Drawdown Comparison

The maximum drawdown for OTLK was -99.98%, occurring on Mar 24, 2026. This drawdown has not yet recovered.

The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.

The current OTLK drawdown is -99.85%. The current SPY drawdown is -2.57%.

RankOTLKSPY
#1-99.98%
Sep 6, 2016 - Mar 24, 2026
-55.20%
Oct 9, 2007 - Aug 16, 2012
#2-29.29%
Jun 16, 2016 - Aug 31, 2016
-47.50%
Mar 24, 2000 - Oct 26, 2006
#3-3.06%
Sep 1, 2016 - Sep 6, 2016
-33.70%
Feb 19, 2020 - Aug 10, 2020
#4-1.71%
Jun 14, 2016 - Jun 16, 2016
-24.50%
Jan 3, 2022 - Dec 13, 2023
#5N/A-19.34%
Sep 20, 2018 - Apr 12, 2019
#6N/A-18.76%
Feb 19, 2025 - Jun 26, 2025
#7N/A-13.02%
Jul 20, 2015 - Apr 18, 2016
#8N/A-10.10%
Jan 26, 2018 - Aug 6, 2018
#9N/A-9.44%
Sep 2, 2020 - Nov 11, 2020
#10N/A-9.30%
Jan 19, 2000 - Mar 17, 2000
#11N/A-9.05%
Jul 19, 2007 - Oct 5, 2007
#12N/A-8.88%
Jan 27, 2026 - Apr 14, 2026
#13N/A-8.41%
Jul 16, 2024 - Sep 19, 2024
#14N/A-7.35%
Sep 14, 2012 - Jan 2, 2013
#15N/A-7.27%
Sep 18, 2014 - Oct 31, 2014

Correlation

Correlation between OTLK and SPY is -0.58 which considered as a moderate negative correlation - the stocks show some tendency to move in opposite directions.

-0.58
-101

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