ONC vs ALNY

Comparison between BeiGene Ltd (ONC, Company) and Alnylam Pharmaceuticals Inc (ALNY, Company).

Both ONC and ALNY are from the Healthcare sector.

5-Year PerformanceALNY has outperformed ONC, delivering a return of +4.3% compared to -1.7%

ONC vs ALNY - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	ONC(COMPANY)	ALNY(COMPANY)
Market Cap	$38B	$38B
Max Drawdown	69.96%	83.58%
Sharpe Ratio	0.21	-1.11
5Y Beta	0.54	0.79
Industry	Biotechnology	Biotechnology
P/E Ratio	73.10	121.13
Forward P/E	47.85	23.42
PEG Ratio	N/A	0.51
Debt to Equity	24.13%	0.00%
Free Cash Flow Yield	2.23%	1.23%
P/S Ratio	5.82	8.93
P/B Ratio	7.13	35.81

Market Cap

ONC

$38B

Winner

ALNY

$38B

Max Drawdown

Winner

ONC

69.96%

ALNY

83.58%

Sharpe Ratio

Winner

ONC

0.21

ALNY

-1.11

5Y Beta

Winner

ONC

0.54

ALNY

0.79

Industry

ONC

Biotechnology

ALNY

Biotechnology

P/E Ratio

Winner

ONC

73.10

ALNY

121.13

Forward P/E

ONC

47.85

Winner

ALNY

23.42

PEG Ratio

ONC

N/A

ALNY

0.51

Debt to Equity

ONC

24.13%

Winner

ALNY

0.00%

Free Cash Flow Yield

Winner

ONC

2.23%

ALNY

1.23%

P/S Ratio

Winner

ONC

5.82

ALNY

8.93

P/B Ratio

Winner

ONC

7.13

ALNY

35.81

ONC vs ALNY - Historical Returns

Returns include dividend reinvestment.

Period	ONC	ALNY
1 month	+5.42%	-29.56%
3 months	+5.60%	-26.05%
6 months	-9.41%	-37.37%
1 year	+3.11%	-47.48%
5 years(CAGR)	-1.68%	+4.27%
10 years(CAGR)	+28.00%	+11.94%
Max(CAGR)	+25.75%	+16.83%

Winner

ONC

+5.42%

ALNY

-29.56%

Winner

ONC

+5.60%

ALNY

-26.05%

Winner

ONC

-9.41%

ALNY

-37.37%

Winner

ONC

+3.11%

ALNY

-47.48%

5Y(CAGR)

ONC

-1.68%

Winner

ALNY

+4.27%

10Y(CAGR)

Winner

ONC

+28.00%

ALNY

+11.94%

Max(CAGR)

Winner

ONC

+25.75%

ALNY

+16.83%

ONC vs ALNY - Annual Returns (2004 - 2026)

Returns include dividend reinvestment.

Year	ONC	ALNY
2026	+0.88%	-44.94%
2025	+65.11%	+70.21%
2024	+4.36%	+20.72%
2023	-20.42%	-18.06%
2022	-18.41%	+36.65%
2021	+3.80%	+32.38%
2020	+55.73%	+12.41%
2019	+21.86%	+58.29%
2018	+39.13%	-44.70%
2017	+214.72%	+228.80%
2016	+7.20%	-59.75%
2015	N/A	-3.71%
2014	N/A	+51.89%
2013	N/A	+235.42%
2012	N/A	+110.74%
2011	N/A	-18.58%
2010	N/A	-45.64%
2009	N/A	-29.94%
2008	N/A	-14.49%
2007	N/A	+34.82%
2006	N/A	+65.12%
2005	N/A	+76.25%
2004	N/A	+6.71%

ONC vs ALNY Drawdown Comparison

The maximum drawdown for ONC was -69.96%, occurring on May 11, 2022. This drawdown has not yet recovered.

The maximum drawdown for ALNY was -83.58%, occurring on Oct 3, 2011. Recovery took 1443 trading sessions.

The current ONC drawdown is -22.17%. The current ALNY drawdown is -55.15%.

Rank	ONC	ALNY
#1	-69.96% Sep 17, 2021 - May 11, 2022	-83.58% Oct 9, 2007 - Jul 3, 2013
#2	-50.63% Jun 8, 2018 - Jul 14, 2020	-77.36% Jun 22, 2015 - Nov 10, 2017
#3	-34.68% Feb 16, 2021 - Sep 16, 2021	-58.17% Oct 20, 2025 - Jul 30, 2026
#4	-30.62% Oct 10, 2017 - Jan 18, 2018	-57.81% Mar 20, 2018 - Jun 19, 2020
#5	-30.10% Oct 16, 2020 - Jan 14, 2021	-52.18% Jun 9, 2004 - Jan 6, 2005
#6	-29.28% Feb 5, 2016 - Nov 10, 2016	-47.61% Jan 13, 2014 - Oct 24, 2014
#7	-26.96% Nov 16, 2016 - Feb 14, 2017	-42.46% Oct 14, 2021 - Aug 3, 2022
#8	-18.35% Jul 20, 2020 - Sep 15, 2020	-40.61% Dec 21, 2022 - Jun 26, 2024
#9	-15.57% Aug 8, 2017 - Sep 15, 2017	-36.52% Mar 29, 2006 - Oct 31, 2006
#10	-15.53% Jan 25, 2021 - Feb 10, 2021	-36.33% Dec 8, 2006 - Jul 11, 2007
#11	-12.11% Feb 1, 2018 - Feb 21, 2018	-34.67% Sep 12, 2005 - Jan 10, 2006
#12	-11.21% Feb 16, 2017 - Apr 28, 2017	-32.55% Jan 10, 2005 - Sep 7, 2005
#13	-10.84% Mar 21, 2018 - May 2, 2018	-26.79% Jan 25, 2021 - Jun 18, 2021
#14	-10.74% Apr 28, 2017 - Jun 2, 2017	-26.77% Jul 20, 2020 - Jan 12, 2021
#15	-10.36% Nov 10, 2016 - Nov 15, 2016	-25.36% Oct 16, 2024 - May 30, 2025