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NVAX vs SEPN

Comparison between Novavax Inc (NVAX, Company) and Septerna Inc (SEPN, Company).

Both NVAX and SEPN are from the Healthcare sector.

NVAX vs SEPN - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap
Winner
NVAX
$1.56B
SEPN
$1.55B
Max Drawdown
NVAX
98.82%
Winner
SEPN
81.47%
Sharpe Ratio
NVAX
0.75
Winner
SEPN
1.94
5Y Beta
NVAX
1.47
Winner
SEPN
1.25
Industry
NVAX
Biotechnology
SEPN
Biotechnology
P/E Ratio
NVAX
-17.56
Winner
SEPN
-42.93
Forward P/E
Winner
NVAX
2.58
SEPN
107.53
PEG Ratio
NVAX
1.32
SEPN
N/A
5Y EPS CAGR
NVAX
-42.97%
SEPN
N/A
Debt to Equity
Winner
NVAX
-201.05%
SEPN
0.00%
Free Cash Flow Yield
NVAX
-5.89%
Winner
SEPN
6.88%
P/S Ratio
Winner
NVAX
2.61
SEPN
21.59
P/B Ratio
NVAX
41.23
Winner
SEPN
4.13

NVAX vs SEPN - Historical Returns

Returns include dividend reinvestment.

1M
NVAX
+9.74%
Winner
SEPN
+17.82%
3M
NVAX
+18.55%
Winner
SEPN
+44.24%
6M
NVAX
+24.15%
Winner
SEPN
+35.67%
1Y
NVAX
+43.12%
Winner
SEPN
+230.23%
5Y(CAGR)
NVAX
-44.88%
SEPN
N/A
10Y(CAGR)
NVAX
-24.11%
SEPN
N/A
Max(CAGR)
NVAX
-8.46%
Winner
SEPN
+35.48%

NVAX vs SEPN - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

YearNVAXSEPN
2026+32.68%+28.06%
2025-21.59%+30.59%
2024+59.84%+7.01%
2023-50.97%N/A
2022-92.81%N/A
2021+26.63%N/A
2020+2383.52%N/A
2019-89.90%N/A
2018+41.54%N/A
2017-2.36%N/A
2016-84.01%N/A
2015+45.66%N/A
2014+13.82%N/A
2013+159.90%N/A
2012+36.96%N/A
2011-50.97%N/A
2010-13.52%N/A
2009+31.68%N/A
2008-42.02%N/A
2007-13.95%N/A
2006+5.67%N/A
2005+18.83%N/A
2004-45.76%N/A
2003+114.29%N/A
2002-80.91%N/A
2001+67.66%N/A
2000+47.83%N/A
1999+12.40%N/A

NVAX vs SEPN Drawdown Comparison

The maximum drawdown for NVAX was -98.82%, occurring on Feb 5, 2024. This drawdown has not yet recovered.

The maximum drawdown for SEPN was -81.47%, occurring on Apr 1, 2025. Recovery took 230 trading sessions.

The current NVAX drawdown is -97.04%. The current SEPN drawdown is -4.04%.

RankNVAXSEPN
#1-98.82%
Feb 8, 2021 - Feb 5, 2024
-81.47%
Dec 23, 2024 - Nov 24, 2025
#2-98.77%
Oct 9, 2001 - Feb 8, 2021
-25.18%
Feb 24, 2026 - May 28, 2026
#3-58.91%
Mar 8, 2000 - Aug 3, 2001
-21.10%
Dec 19, 2025 - Feb 17, 2026
#4-28.27%
Sep 10, 2001 - Oct 3, 2001
-16.77%
Dec 4, 2024 - Dec 23, 2024
#5-18.43%
Nov 5, 1999 - Dec 16, 1999
-16.19%
Nov 7, 2024 - Dec 4, 2024
#6-12.63%
Dec 17, 1999 - Jan 20, 2000
-13.97%
Nov 26, 2025 - Dec 19, 2025
#7-10.34%
Jan 21, 2000 - Feb 8, 2000
-10.63%
Feb 17, 2026 - Feb 24, 2026
#8-8.57%
Aug 22, 2001 - Sep 10, 2001
-10.36%
Jun 26, 2026 - Jul 6, 2026
#9-8.06%
Feb 11, 2000 - Mar 1, 2000
-6.45%
Oct 25, 2024 - Oct 31, 2024
#10-6.68%
Mar 6, 2000 - Mar 8, 2000
-5.55%
Jun 23, 2026 - Jun 26, 2026
#11-5.02%
Oct 3, 2001 - Oct 9, 2001
-4.76%
Oct 31, 2024 - Nov 4, 2024
#12-3.72%
Aug 6, 2001 - Aug 9, 2001
-3.65%
Jun 18, 2026 - Jun 23, 2026
#13-2.91%
Aug 13, 2001 - Aug 22, 2001
-3.57%
May 28, 2026 - Jun 4, 2026
#14-1.86%
Mar 2, 2000 - Mar 6, 2000
-3.45%
Nov 4, 2024 - Nov 6, 2024
#15N/A-3.06%
Jun 4, 2026 - Jun 11, 2026

Correlation

Correlation between NVAX and SEPN is 0.63 which considered as a moderate positive correlation - the stocks show some tendency to move together.

0.63
-101

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