NRXP vs SPRO

Comparison between NRX Pharmaceuticals Inc (NRXP, Company) and Spero Therapeutics Inc (SPRO, Company).

Both NRXP and SPRO are from the Healthcare sector.

5-Year PerformanceSPRO has outperformed NRXP, delivering a return of -31.1% compared to -51.5%

NRXP vs SPRO - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	NRXP(COMPANY)	SPRO(COMPANY)
Market Cap	$133M	$132M
Max Drawdown	99.82%	97.46%
Sharpe Ratio	0.57	-0.17
5Y Beta	1.06	0.69
Industry	Biotechnology	Biotechnology
P/E Ratio	-3.46	8.35
Forward P/E	34.25	N/A
5Y Dividends CAGR	N/A	30.26%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-11.23%	5.49%

Market Cap

Winner

NRXP

$133M

SPRO

$132M

Max Drawdown

NRXP

99.82%

Winner

SPRO

97.46%

Sharpe Ratio

Winner

NRXP

0.57

SPRO

-0.17

5Y Beta

NRXP

1.06

Winner

SPRO

0.69

Industry

NRXP

Biotechnology

SPRO

Biotechnology

P/E Ratio

Winner

NRXP

-3.46

SPRO

8.35

Forward P/E

NRXP

34.25

SPRO

N/A

5Y Dividends CAGR

NRXP

N/A

SPRO

30.26%

Debt to Equity

NRXP

0.00%

SPRO

0.00%

Free Cash Flow Yield

NRXP

-11.23%

Winner

SPRO

5.49%

NRXP vs SPRO - Historical Returns

Returns include dividend reinvestment.

Period	NRXP	SPRO
1 month	+27.45%	-11.63%
3 months	+108.95%	-7.32%
6 months	+82.11%	-0.44%
1 year	+22.91%	-22.45%
5 years(CAGR)	-51.55%	-31.09%
10 years(CAGR)	-31.14%	-4.16%
Max(CAGR)	-31.14%	-1.34%

Winner

NRXP

+27.45%

SPRO

-11.63%

Winner

NRXP

+108.95%

SPRO

-7.32%

Winner

NRXP

+82.11%

SPRO

-0.44%

Winner

NRXP

+22.91%

SPRO

-22.45%

5Y(CAGR)

NRXP

-51.55%

Winner

SPRO

-31.09%

10Y(CAGR)

NRXP

-31.14%

Winner

SPRO

-4.16%

Max(CAGR)

NRXP

-31.14%

Winner

SPRO

-1.34%

NRXP vs SPRO - Annual Returns (2004 - 2026)

Returns include dividend reinvestment.

Year	NRXP	SPRO
2026	+51.53%	-2.98%
2025	-9.36%	+115.74%
2024	-55.91%	-32.24%
2023	-61.98%	-15.52%
2022	-77.67%	-88.58%
2021	-80.09%	-10.71%
2020	+130.19%	+96.45%
2019	+4.33%	+53.59%
2018	+5.26%	-49.34%
2017	+0.83%	+2.17%
2015	N/A	+125.03%
2014	N/A	-36.85%
2013	N/A	+87.73%
2012	N/A	-15.94%
2011	N/A	-18.88%
2010	N/A	-29.17%
2009	N/A	+37.55%
2008	N/A	-59.66%
2007	N/A	+44.06%
2006	N/A	+26.56%
2005	N/A	-15.34%
2004	N/A	+7.04%

NRXP vs SPRO Drawdown Comparison

The maximum drawdown for NRXP was -99.82%, occurring on Nov 14, 2024. This drawdown has not yet recovered.

The maximum drawdown for SPRO was -97.46%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The current NRXP drawdown is -99.37%. The current SPRO drawdown is -89.67%.

Rank	NRXP	SPRO
#1	-99.82% Feb 2, 2021 - Nov 14, 2024	-97.46% Dec 28, 2020 - Apr 8, 2025
#2	-40.43% Dec 22, 2020 - Jan 20, 2021	-85.13% Jul 17, 2007 - Nov 2, 2017
#3	-21.33% Jan 21, 2021 - Jan 28, 2021	-70.48% Apr 12, 2018 - Dec 8, 2020
#4	-13.88% Dec 14, 2020 - Dec 17, 2020	-42.56% May 17, 2005 - Feb 16, 2007
#5	-11.39% Apr 29, 2020 - Dec 14, 2020	-32.47% Nov 13, 2017 - Apr 9, 2018
#6	-10.15% Jan 17, 2020 - Apr 29, 2020	-18.79% Mar 12, 2007 - Jun 19, 2007
#7	-4.63% Jun 17, 2019 - Jan 17, 2020	-9.16% Jun 25, 2007 - Jul 3, 2007
#8	-2.24% Dec 17, 2020 - Dec 21, 2020	-8.75% Dec 3, 2004 - Mar 28, 2005
#9	-1.52% May 24, 2019 - Jun 17, 2019	-5.73% Feb 21, 2007 - Mar 7, 2007
#10	-1.12% Mar 1, 2018 - May 21, 2018	-5.34% Dec 8, 2020 - Dec 16, 2020
#11	-0.86% Dec 15, 2017 - Feb 12, 2018	-4.94% Mar 28, 2005 - May 11, 2005
#12	-0.58% Apr 26, 2019 - May 24, 2019	-4.48% Dec 17, 2020 - Dec 21, 2020
#13	-0.50% Jul 26, 2018 - Sep 14, 2018	-4.01% Jul 9, 2007 - Jul 13, 2007
#14	-0.49% Nov 15, 2018 - Dec 21, 2018	-2.82% Nov 22, 2004 - Nov 24, 2004
#15	-0.41% Feb 12, 2018 - Feb 27, 2018	-2.50% Nov 24, 2004 - Dec 1, 2004