NBIX vs NIO

Comparison between Neurocrine Biosciences Inc (NBIX, Company) and NIO Inc (NIO, Company).

NBIX is from the Healthcare sector, while NIO is from the Consumer Cyclical sector.

5-Year PerformanceNBIX has outperformed NIO, delivering a return of +10.9% compared to -29.7%

NBIX vs NIO - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	NBIX(COMPANY)	NIO(COMPANY)
Market Cap	$16B	$16B
Max Drawdown	97.21%	95.00%
Sharpe Ratio	0.92	0.88
5Y Beta	0.82	1.00
Industry	Drug Manufacturers - Specialty & Generic	Auto Manufacturers
P/E Ratio	24.11	-7.57
Forward P/E	21.60	384.62
PEG Ratio	0.20	N/A
5Y EPS CAGR	9.25%	10.16%
Debt to Equity	0.00%	223.16%
Free Cash Flow Yield	5.09%	2.64%
P/S Ratio	5.23	0.18
P/B Ratio	4.49	24.00

Market Cap

Winner

NBIX

$16B

NIO

$16B

Max Drawdown

NBIX

97.21%

Winner

NIO

95.00%

Sharpe Ratio

Winner

NBIX

0.92

NIO

0.88

5Y Beta

Winner

NBIX

0.82

NIO

1.00

Industry

NBIX

Drug Manufacturers - Specialty & Generic

NIO

Auto Manufacturers

P/E Ratio

NBIX

24.11

Winner

NIO

-7.57

Forward P/E

Winner

NBIX

21.60

NIO

384.62

PEG Ratio

NBIX

0.20

NIO

N/A

5Y EPS CAGR

NBIX

9.25%

Winner

NIO

10.16%

Debt to Equity

Winner

NBIX

0.00%

NIO

223.16%

Free Cash Flow Yield

Winner

NBIX

5.09%

NIO

2.64%

P/S Ratio

NBIX

5.23

Winner

NIO

0.18

P/B Ratio

Winner

NBIX

4.49

NIO

24.00

NBIX vs NIO - Historical Returns

Returns include dividend reinvestment.

Period	NBIX	NIO
1 month	+17.98%	-13.91%
3 months	+22.46%	+19.76%
6 months	+13.40%	-1.67%
1 year	+28.00%	+45.54%
5 years(CAGR)	+10.88%	-29.68%
10 years(CAGR)	+13.17%	N/A
Max(CAGR)	+12.44%	-1.49%

Winner

NBIX

+17.98%

NIO

-13.91%

Winner

NBIX

+22.46%

NIO

+19.76%

Winner

NBIX

+13.40%

NIO

-1.67%

NBIX

+28.00%

Winner

NIO

+45.54%

5Y(CAGR)

Winner

NBIX

+10.88%

NIO

-29.68%

10Y(CAGR)

NBIX

+13.17%

NIO

N/A

Max(CAGR)

Winner

NBIX

+12.44%

NIO

-1.49%

NBIX vs NIO - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	NBIX	NIO
2026	+11.81%	+14.40%
2025	+2.88%	+12.09%
2024	+3.62%	-48.22%
2023	+9.73%	-5.82%
2022	+35.01%	-70.87%
2021	-11.16%	-40.77%
2020	-11.50%	+1210.22%
2019	+53.36%	-35.16%
2018	-9.95%	-3.48%
2017	+100.70%	N/A
2016	-26.07%	N/A
2015	+147.68%	N/A
2014	+133.93%	N/A
2013	+14.74%	N/A
2012	-12.51%	N/A
2011	+10.82%	N/A
2010	+184.01%	N/A
2009	-16.82%	N/A
2008	-29.20%	N/A
2007	-55.79%	N/A
2006	-83.61%	N/A
2005	+27.97%	N/A
2004	-11.17%	N/A
2003	+20.11%	N/A
2002	-9.71%	N/A
2001	+59.40%	N/A
2000	+33.86%	N/A
1999	+253.57%	N/A

NBIX vs NIO Drawdown Comparison

The maximum drawdown for NBIX was -97.21%, occurring on Nov 12, 2009. Recovery took 2931 trading sessions.

The maximum drawdown for NIO was -95.00%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The current NBIX drawdown is -2.55%. The current NIO drawdown is -90.64%.

Rank	NBIX	NIO
#1	-97.21% Mar 15, 2006 - Nov 2, 2017	-95.00% Feb 9, 2021 - Apr 8, 2025
#2	-66.15% Mar 3, 2000 - Nov 20, 2001	-88.62% Sep 13, 2018 - Jul 7, 2020
#3	-54.12% Dec 24, 2001 - Jun 5, 2003	-26.00% Nov 23, 2020 - Jan 8, 2021
#4	-50.71% Apr 27, 2004 - Feb 27, 2006	-25.97% Jul 10, 2020 - Aug 25, 2020
#5	-46.39% Jul 15, 2020 - Jan 17, 2024	-16.68% Aug 26, 2020 - Sep 29, 2020
#6	-45.71% Sep 4, 2018 - Jun 19, 2020	-11.05% Jan 11, 2021 - Feb 9, 2021
#7	-42.89% Jan 30, 2025 - Nov 5, 2025	-8.67% Oct 16, 2020 - Oct 29, 2020
#8	-28.57% Jan 21, 2000 - Feb 16, 2000	-7.74% Nov 12, 2020 - Nov 19, 2020
#9	-27.12% Aug 1, 2024 - Jan 30, 2025	-5.61% Nov 9, 2020 - Nov 12, 2020
#10	-22.86% Dec 2, 1999 - Dec 13, 1999	-5.01% Oct 1, 2020 - Oct 12, 2020
#11	-21.32% Jun 16, 2003 - Jan 23, 2004	-4.41% Oct 29, 2020 - Nov 2, 2020
#12	-20.90% Dec 10, 2025 - May 12, 2026	-2.57% Jul 7, 2020 - Jul 9, 2020
#13	-19.01% Dec 29, 1999 - Jan 10, 2000	-1.70% Nov 5, 2020 - Nov 9, 2020
#14	-18.53% Mar 9, 2018 - May 15, 2018	-1.05% Oct 12, 2020 - Oct 14, 2020
#15	-13.74% Jan 26, 2004 - Mar 4, 2004	N/A

Correlation

Correlation between NBIX and NIO is -0.36 which considered as a weak negative correlation - the stocks show a slight tendency to move in opposite directions.

-0.36

-101