NAGE vs AGEN

Comparison between Niagen Bioscience Inc (NAGE, Company) and Agenus Inc (AGEN, Company).

Both NAGE and AGEN are from the Healthcare sector.

5-Year PerformanceNAGE has outperformed AGEN, delivering a return of -17.1% compared to -40.6%

NAGE vs AGEN - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	NAGE(COMPANY)	AGEN(COMPANY)
Market Cap	$256M	$255M
Max Drawdown	97.00%	99.98%
Sharpe Ratio	-1.93	0.66
5Y Beta	1.67	1.11
Industry	Biotechnology	Biotechnology
P/E Ratio	13.75	3.98
Forward P/E	13.61	3.61
PEG Ratio	0.48	1.44
Debt to Equity	0.00%	-27.30%
Free Cash Flow Yield	1.73%	-34.27%
P/S Ratio	1.97	2.23
P/B Ratio	3.18	218.61

Market Cap

Winner

NAGE

$256M

AGEN

$255M

Max Drawdown

Winner

NAGE

97.00%

AGEN

99.98%

Sharpe Ratio

NAGE

-1.93

Winner

AGEN

0.66

5Y Beta

NAGE

1.67

Winner

AGEN

1.11

Industry

NAGE

Biotechnology

AGEN

Biotechnology

P/E Ratio

NAGE

13.75

Winner

AGEN

3.98

Forward P/E

NAGE

13.61

Winner

AGEN

3.61

PEG Ratio

Winner

NAGE

0.48

AGEN

1.44

Debt to Equity

NAGE

0.00%

Winner

AGEN

-27.30%

Free Cash Flow Yield

Winner

NAGE

1.73%

AGEN

-34.27%

P/S Ratio

Winner

NAGE

1.97

AGEN

2.23

P/B Ratio

Winner

NAGE

3.18

AGEN

218.61

NAGE vs AGEN - Historical Returns

Returns include dividend reinvestment.

Period	NAGE	AGEN
1 month	+2.10%	+119.94%
3 months	-29.90%	+95.31%
6 months	-43.24%	+164.08%
1 year	-63.64%	+35.87%
5 years(CAGR)	-17.11%	-40.62%
10 years(CAGR)	-1.31%	-23.62%
Max(CAGR)	-5.25%	-22.03%

NAGE

+2.10%

Winner

AGEN

+119.94%

NAGE

-29.90%

Winner

AGEN

+95.31%

NAGE

-43.24%

Winner

AGEN

+164.08%

NAGE

-63.64%

Winner

AGEN

+35.87%

5Y(CAGR)

Winner

NAGE

-17.11%

AGEN

-40.62%

10Y(CAGR)

Winner

NAGE

-1.31%

AGEN

-23.62%

Max(CAGR)

Winner

NAGE

-5.25%

AGEN

-22.03%

NAGE vs AGEN - Annual Returns (2000 - 2026)

Returns include dividend reinvestment.

Year	NAGE	AGEN
2026	-45.60%	+132.20%
2025	+16.06%	+1.62%
2024	+270.98%	-82.88%
2023	-15.38%	-64.85%
2022	-57.14%	-30.84%
2021	-21.26%	-0.31%
2020	+11.63%	-21.29%
2019	+26.39%	+62.15%
2018	-45.98%	-32.77%
2017	+70.43%	-21.63%
2016	-9.56%	-7.62%
2015	+35.56%	+14.07%
2014	-37.52%	+42.81%
2013	+182.79%	-37.74%
2012	-11.67%	+88.94%
2011	-59.56%	-68.55%
2010	+202.22%	+57.17%
2009	-62.39%	+33.33%
2008	-61.00%	-76.92%
2007	N/A	+6.25%
2006	N/A	-61.80%
2005	N/A	-52.40%
2004	N/A	-11.69%
2003	N/A	+5.98%
2002	N/A	-33.89%
2001	N/A	+48.28%
2000	N/A	-76.09%

NAGE vs AGEN Drawdown Comparison

The maximum drawdown for NAGE was -97.00%, occurring on Aug 3, 2009. Recovery took 3150 trading sessions.

The maximum drawdown for AGEN was -99.98%, occurring on Mar 31, 2025. This drawdown has not yet recovered.

The current NAGE drawdown is -81.86%. The current AGEN drawdown is -99.88%.

Rank	NAGE	AGEN
#1	-97.00% Aug 19, 2008 - Feb 25, 2021	-99.98% Mar 9, 2000 - Mar 31, 2025
#2	-93.65% Feb 25, 2021 - Sep 26, 2022	-23.90% Feb 16, 2000 - Mar 9, 2000
#3	-25.00% Jul 15, 2008 - Jul 22, 2008	-6.50% Feb 10, 2000 - Feb 15, 2000
#4	-22.22% Jul 22, 2008 - Aug 19, 2008	-4.86% Feb 8, 2000 - Feb 10, 2000