MSTR vs ALNY

Comparison between Microstrategy Inc - Class A (MSTR, Company) and Alnylam Pharmaceuticals Inc (ALNY, Company).

MSTR is from the Technology sector, while ALNY is from the Healthcare sector.

5-Year PerformanceMSTR has outperformed ALNY, delivering a return of +15.8% compared to +11.6%

MSTR vs ALNY - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	MSTR(COMPANY)	ALNY(COMPANY)
Market Cap	$39B	$39B
Max Drawdown	99.86%	83.58%
Sharpe Ratio	-1.30	-0.07
5Y Beta	2.47	0.80
Industry	Software - Application	Biotechnology
P/E Ratio	-14.78	123.07
Forward P/E	1.60	30.30
PEG Ratio	-0.13	0.51
Debt to Equity	22.36%	0.00%
Free Cash Flow Yield	-0.15%	1.21%
P/S Ratio	84.30	9.27
P/B Ratio	1.13	36.96

Market Cap

MSTR

$39B

Winner

ALNY

$39B

Max Drawdown

MSTR

99.86%

Winner

ALNY

83.58%

Sharpe Ratio

MSTR

-1.30

Winner

ALNY

-0.07

5Y Beta

MSTR

2.47

Winner

ALNY

0.80

Industry

MSTR

Software - Application

ALNY

Biotechnology

P/E Ratio

Winner

MSTR

-14.78

ALNY

123.07

Forward P/E

Winner

MSTR

1.60

ALNY

30.30

PEG Ratio

Winner

MSTR

-0.13

ALNY

0.51

Debt to Equity

MSTR

22.36%

Winner

ALNY

0.00%

Free Cash Flow Yield

MSTR

-0.15%

Winner

ALNY

1.21%

P/S Ratio

MSTR

84.30

Winner

ALNY

9.27

P/B Ratio

Winner

MSTR

1.13

ALNY

36.96

MSTR vs ALNY - Historical Returns

Returns include dividend reinvestment.

Period	MSTR	ALNY
1 month	-26.08%	+0.29%
3 months	-11.10%	-9.76%
6 months	-19.09%	-26.49%
1 year	-65.69%	-6.79%
5 years(CAGR)	+15.77%	+11.57%
10 years(CAGR)	+21.65%	+17.15%
Max(CAGR)	+3.77%	+18.37%

MSTR

-26.08%

Winner

ALNY

+0.29%

MSTR

-11.10%

Winner

ALNY

-9.76%

Winner

MSTR

-19.09%

ALNY

-26.49%

MSTR

-65.69%

Winner

ALNY

-6.79%

5Y(CAGR)

Winner

MSTR

+15.77%

ALNY

+11.57%

10Y(CAGR)

Winner

MSTR

+21.65%

ALNY

+17.15%

Max(CAGR)

MSTR

+3.77%

Winner

ALNY

+18.37%

MSTR vs ALNY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	MSTR	ALNY
2026	-16.56%	-28.08%
2025	-49.35%	+70.21%
2024	+322.71%	+20.72%
2023	+335.54%	-18.06%
2022	-74.64%	+36.65%
2021	+28.05%	+32.38%
2020	+169.25%	+12.41%
2019	+10.94%	+58.29%
2018	-3.07%	-44.70%
2017	-33.63%	+228.80%
2016	+15.35%	-59.75%
2015	+9.91%	-3.71%
2014	+31.47%	+51.89%
2013	+30.11%	+235.42%
2012	-16.09%	+110.74%
2011	+22.58%	-18.58%
2010	-11.12%	-45.64%
2009	+152.20%	-29.94%
2008	-58.78%	-14.49%
2007	-17.58%	+34.82%
2006	+31.03%	+65.12%
2005	+41.44%	+76.25%
2004	+16.43%	+6.71%
2003	+230.27%	N/A
2002	-61.18%	N/A
2001	-59.47%	N/A
2000	-90.89%	N/A
1999	+114.55%	N/A

MSTR vs ALNY Drawdown Comparison

The maximum drawdown for MSTR was -99.86%, occurring on Jul 26, 2002. Recovery took 6207 trading sessions.

The maximum drawdown for ALNY was -83.58%, occurring on Oct 3, 2011. Recovery took 1443 trading sessions.

The current MSTR drawdown is -72.32%. The current ALNY drawdown is -41.41%.

Rank	MSTR	ALNY
#1	-99.86% Mar 10, 2000 - Nov 11, 2024	-83.58% Oct 9, 2007 - Jul 3, 2013
#2	-77.42% Nov 20, 2024 - Feb 5, 2026	-77.36% Jun 22, 2015 - Nov 10, 2017
#3	-29.10% Dec 10, 1999 - Jan 10, 2000	-57.81% Mar 20, 2018 - Jun 19, 2020
#4	-20.42% Feb 16, 2000 - Mar 1, 2000	-52.18% Jun 9, 2004 - Jan 6, 2005
#5	-17.27% Nov 3, 1999 - Nov 22, 1999	-47.61% Jan 13, 2014 - Oct 24, 2014
#6	-14.35% Jan 28, 2000 - Feb 8, 2000	-42.46% Oct 14, 2021 - Aug 3, 2022
#7	-9.76% Nov 29, 1999 - Dec 3, 1999	-42.42% Oct 20, 2025 - Jun 12, 2026
#8	-9.65% Jan 10, 2000 - Jan 19, 2000	-40.61% Dec 21, 2022 - Jun 26, 2024
#9	-8.11% Nov 12, 2024 - Nov 18, 2024	-36.52% Mar 29, 2006 - Oct 31, 2006
#10	-7.59% Dec 6, 1999 - Dec 8, 1999	-36.33% Dec 8, 2006 - Jul 11, 2007
#11	-2.15% Nov 22, 1999 - Nov 24, 1999	-34.67% Sep 12, 2005 - Jan 10, 2006
#12	-2.12% Jan 21, 2000 - Jan 26, 2000	-32.55% Jan 10, 2005 - Sep 7, 2005
#13	-0.86% Mar 7, 2000 - Mar 9, 2000	-26.79% Jan 25, 2021 - Jun 18, 2021
#14	-0.71% Feb 8, 2000 - Feb 10, 2000	-26.77% Jul 20, 2020 - Jan 12, 2021
#15	N/A	-25.36% Oct 16, 2024 - May 30, 2025