MSM vs RYTM

Comparison between MSC Industrial Direct Co. Inc - Class A (MSM, Company) and Rhythm Pharmaceuticals Inc (RYTM, Company).

MSM is from the Industrials sector, while RYTM is from the Healthcare sector.

5-Year PerformanceRYTM has outperformed MSM, delivering a return of +36.4% compared to +10.4%

MSM vs RYTM - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	MSM(COMPANY)	RYTM(COMPANY)
Market Cap	$6.61B	$6.62B
Max Drawdown	57.07%	92.10%
Sharpe Ratio	1.53	0.98
5Y Beta	0.82	0.92
Industry	Industrial Distribution	Biotechnology
P/E Ratio	34.70	-31.81
Forward P/E	22.32	N/A
PEG Ratio	N/A	-2.61
Dividend Yield	2.95%	N/A
5Y Dividends CAGR	-7.89%	N/A
5Y EPS CAGR	-8.84%	17.00%
Debt to Equity	0.00%	88.25%
Free Cash Flow Yield	3.25%	-1.82%

Market Cap

MSM

$6.61B

Winner

RYTM

$6.62B

Max Drawdown

Winner

MSM

57.07%

RYTM

92.10%

Sharpe Ratio

Winner

MSM

1.53

RYTM

0.98

5Y Beta

Winner

MSM

0.82

RYTM

0.92

Industry

MSM

Industrial Distribution

RYTM

Biotechnology

P/E Ratio

MSM

34.70

Winner

RYTM

-31.81

Forward P/E

MSM

22.32

RYTM

N/A

PEG Ratio

MSM

N/A

RYTM

-2.61

Dividend Yield

MSM

2.95%

RYTM

N/A

5Y Dividends CAGR

MSM

-7.89%

RYTM

N/A

5Y EPS CAGR

MSM

-8.84%

Winner

RYTM

17.00%

Debt to Equity

Winner

MSM

0.00%

RYTM

88.25%

Free Cash Flow Yield

Winner

MSM

3.25%

RYTM

-1.82%

MSM vs RYTM - Historical Returns

Returns include dividend reinvestment.

Period	MSM	RYTM
1 month	+13.23%	+11.46%
3 months	+35.99%	+12.73%
6 months	+40.08%	-13.37%
1 year	+50.00%	+57.43%
5 years(CAGR)	+10.36%	+36.39%
10 years(CAGR)	+9.93%	+14.41%
Max(CAGR)	+12.61%	+14.41%

Winner

MSM

+13.23%

RYTM

+11.46%

Winner

MSM

+35.99%

RYTM

+12.73%

Winner

MSM

+40.08%

RYTM

-13.37%

MSM

+50.00%

Winner

RYTM

+57.43%

5Y(CAGR)

MSM

+10.36%

Winner

RYTM

+36.39%

10Y(CAGR)

MSM

+9.93%

Winner

RYTM

+14.41%

Max(CAGR)

MSM

+12.61%

Winner

RYTM

+14.41%

MSM vs RYTM - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	MSM	RYTM
2026	+40.75%	-7.83%
2025	+16.42%	+78.19%
2024	-22.03%	+24.04%
2023	+28.51%	+60.51%
2022	+1.01%	+172.91%
2021	+6.52%	-67.13%
2020	+24.83%	+29.83%
2019	+7.25%	-15.71%
2018	-18.73%	-4.00%
2017	+6.92%	-3.13%
2016	+67.44%	N/A
2015	-29.09%	N/A
2014	+6.04%	N/A
2013	+6.29%	N/A
2012	+7.44%	N/A
2011	+10.56%	N/A
2010	+40.74%	N/A
2009	+23.47%	N/A
2008	-5.08%	N/A
2007	+1.39%	N/A
2006	-4.62%	N/A
2005	+20.64%	N/A
2004	+31.97%	N/A
2003	+53.88%	N/A
2002	-7.79%	N/A
2001	+15.36%	N/A
2000	+33.78%	N/A
1999	+23.95%	N/A

MSM vs RYTM Drawdown Comparison

The maximum drawdown for MSM was -57.07%, occurring on Sep 23, 2002. Recovery took 410 trading sessions.

The maximum drawdown for RYTM was -92.10%, occurring on May 19, 2022. Recovery took 727 trading sessions.

The current RYTM drawdown is -17.71%.

Rank	MSM	RYTM
#1	-57.07% Mar 20, 2002 - Nov 3, 2003	-92.10% Jan 22, 2021 - Dec 12, 2023
#2	-50.77% Jul 9, 2007 - Apr 7, 2010	-63.29% Jul 5, 2018 - Jan 21, 2021
#3	-48.19% Feb 21, 2017 - Nov 24, 2020	-47.22% Jan 29, 2018 - Jun 1, 2018
#4	-47.44% May 31, 2000 - Mar 4, 2002	-35.54% Dec 11, 2025 - Mar 27, 2026
#5	-38.74% Jun 11, 2014 - Nov 23, 2016	-32.48% Feb 12, 2024 - Jul 16, 2024
#6	-32.73% Apr 6, 2011 - Jan 13, 2012	-30.27% Nov 8, 2024 - Jun 6, 2025
#7	-31.14% May 9, 2006 - Jun 1, 2007	-26.67% Oct 5, 2017 - Dec 1, 2017
#8	-30.83% Jan 20, 2000 - May 11, 2000	-24.99% Jun 6, 2018 - Jun 26, 2018
#9	-29.28% Oct 12, 2023 - Feb 6, 2026	-19.92% Dec 27, 2023 - Feb 9, 2024
#10	-26.06% Nov 29, 2004 - Jul 28, 2005	-19.17% Jul 16, 2024 - Sep 19, 2024
#11	-26.03% Mar 28, 2012 - Feb 12, 2013	-15.80% Oct 29, 2025 - Dec 11, 2025
#12	-23.27% Nov 2, 1999 - Dec 8, 1999	-13.83% Dec 18, 2017 - Jan 25, 2018
#13	-21.82% Apr 7, 2010 - Oct 21, 2010	-13.47% Sep 19, 2024 - Nov 5, 2024
#14	-21.27% May 14, 2021 - Apr 17, 2023	-11.19% Jun 26, 2018 - Jul 3, 2018
#15	-15.81% Jul 15, 2004 - Sep 29, 2004	-10.68% Dec 1, 2017 - Dec 18, 2017