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MPLT vs SPY

Comparison between MapLight Therapeutics Inc (MPLT, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).

MPLT vs SPY - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap / Net Assets
MPLT
$1.60B
Winner
SPY
$781B
Expense Ratio
MPLT
N/A
SPY
0.09%
Max Drawdown
Winner
MPLT
30.27%
SPY
56.47%
Sharpe Ratio
Winner
MPLT
1.42
SPY
1.12
5Y Beta
MPLT
1.37
Winner
SPY
1.00
Industry
MPLT
Biotechnology
SPY
N/A
P/E Ratio
Winner
MPLT
-9.65
SPY
28.53
Forward P/E
MPLT
N/A
SPY
21.47
5Y Dividends CAGR
MPLT
N/A
SPY
6.00%
5Y EPS CAGR
MPLT
N/A
SPY
25.58%
Debt to Equity
Winner
MPLT
0.00%
SPY
32.09%
Free Cash Flow Yield
MPLT
-14.17%
SPY
N/A
P/S Ratio
MPLT
N/A
SPY
3.75
P/B Ratio
Winner
MPLT
4.24
SPY
5.64

MPLT vs SPY - Historical Returns

Returns include dividend reinvestment.

1M
Winner
MPLT
+23.01%
SPY
+0.63%
3M
Winner
MPLT
+21.02%
SPY
+4.46%
6M
Winner
MPLT
+95.94%
SPY
+7.67%
1Y
MPLT
N/A
SPY
+17.68%
5Y(CAGR)
MPLT
N/A
SPY
+12.42%
10Y(CAGR)
MPLT
N/A
SPY
+14.84%
Max(CAGR)
Winner
MPLT
+142.64%
SPY
+8.44%

MPLT vs SPY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

YearMPLTSPY
2026+110.08%+8.63%
2025-4.23%+18.00%
2024N/A+25.59%
2023N/A+26.72%
2022N/A-18.64%
2021N/A+30.52%
2020N/A+17.28%
2019N/A+31.09%
2018N/A-5.24%
2017N/A+20.78%
2016N/A+13.59%
2015N/A+1.31%
2014N/A+14.56%
2013N/A+29.00%
2012N/A+14.17%
2011N/A+0.85%
2010N/A+13.14%
2009N/A+22.67%
2008N/A-36.25%
2007N/A+5.32%
2006N/A+13.85%
2005N/A+5.32%
2004N/A+10.75%
2003N/A+24.18%
2002N/A-22.42%
2001N/A-10.13%
2000N/A-8.84%
1999N/A+8.61%

MPLT vs SPY Drawdown Comparison

The maximum drawdown for MPLT was -30.27%, occurring on Nov 25, 2025. Recovery took 25 trading sessions.

The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.

The current MPLT drawdown is -11.48%. The current SPY drawdown is -2.57%.

RankMPLTSPY
#1-30.27%
Oct 30, 2025 - Dec 5, 2025		-55.20%
Oct 9, 2007 - Aug 16, 2012
#2-25.52%
Dec 15, 2025 - Apr 2, 2026		-47.50%
Mar 24, 2000 - Oct 26, 2006
#3-17.52%
Apr 22, 2026 - Jun 26, 2026		-33.70%
Feb 19, 2020 - Aug 10, 2020
#4-11.48%
Jul 9, 2026 - Jul 23, 2026		-24.50%
Jan 3, 2022 - Dec 13, 2023
#5-10.54%
Apr 9, 2026 - Apr 17, 2026		-19.34%
Sep 20, 2018 - Apr 12, 2019
#6-9.76%
Oct 27, 2025 - Oct 30, 2025		-18.76%
Feb 19, 2025 - Jun 26, 2025
#7-8.09%
Apr 17, 2026 - Apr 22, 2026		-13.02%
Jul 20, 2015 - Apr 18, 2016
#8-5.53%
Jul 2, 2026 - Jul 8, 2026		-10.10%
Jan 26, 2018 - Aug 6, 2018
#9-1.54%
Dec 10, 2025 - Dec 12, 2025		-9.44%
Sep 2, 2020 - Nov 11, 2020
#10-0.22%
Dec 5, 2025 - Dec 9, 2025		-9.30%
Jan 19, 2000 - Mar 17, 2000
#11N/A-9.05%
Jul 19, 2007 - Oct 5, 2007
#12N/A-8.88%
Jan 27, 2026 - Apr 14, 2026
#13N/A-8.41%
Jul 16, 2024 - Sep 19, 2024
#14N/A-7.35%
Sep 14, 2012 - Jan 2, 2013
#15N/A-7.27%
Sep 18, 2014 - Oct 31, 2014

Correlation

Correlation between MPLT and SPY is 0.85 which considered as a strong positive correlation - the stocks tend to move together.

0.85
-101

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