MPLT vs SEPN
Comparison between MapLight Therapeutics Inc (MPLT, Company) and Septerna Inc (SEPN, Company).
Both MPLT and SEPN are from the Healthcare sector.
MPLT vs SEPN - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap
MPLT
$1.34B
Winner
SEPN
$1.34B
Max Drawdown
Winner
MPLT
30.27%
SEPN
81.47%
Sharpe Ratio
MPLT
1.18
Winner
SEPN
2.08
5Y Beta
MPLT
1.46
Winner
SEPN
1.30
Industry
MPLT
Biotechnology
SEPN
Biotechnology
P/E Ratio
MPLT
-8.07
Winner
SEPN
-36.95
Forward P/E
MPLT
N/A
SEPN
107.53
Debt to Equity
MPLT
0.00%
SEPN
0.00%
Free Cash Flow Yield
MPLT
-16.93%
Winner
SEPN
7.99%
P/S Ratio
MPLT
N/A
SEPN
18.84
P/B Ratio
Winner
MPLT
3.38
SEPN
3.59
MPLT vs SEPN - Historical Returns
Returns include dividend reinvestment.
1M
MPLT
+0.32%
Winner
SEPN
+29.09%
3M
Winner
MPLT
+55.96%
SEPN
+13.40%
6M
Winner
MPLT
+51.49%
SEPN
+16.41%
1Y
MPLT
N/A
SEPN
+196.10%
Max(CAGR)
Winner
MPLT
+101.35%
SEPN
+26.26%
MPLT vs SEPN - Annual Returns (2024 - 2026)
Returns include dividend reinvestment.
| Year | MPLT | SEPN |
|---|---|---|
| 2026 | +67.02% | +11.33% |
| 2025 | -4.23% | +30.59% |
| 2024 | N/A | +7.01% |
MPLT vs SEPN Drawdown Comparison
The maximum drawdown for MPLT was -30.27%, occurring on Nov 25, 2025. Recovery took 25 trading sessions.
The maximum drawdown for SEPN was -81.47%, occurring on Apr 1, 2025. Recovery took 230 trading sessions.
The current MPLT drawdown is -12.82%. The current SEPN drawdown is -0.70%.
| Rank | MPLT | SEPN |
|---|---|---|
| #1 | -30.27% Oct 30, 2025 - Dec 5, 2025 | -81.47% Dec 23, 2024 - Nov 24, 2025 |
| #2 | -25.52% Dec 15, 2025 - Apr 2, 2026 | -25.18% Feb 24, 2026 - May 28, 2026 |
| #3 | -17.52% Apr 22, 2026 - May 18, 2026 | -21.10% Dec 19, 2025 - Feb 17, 2026 |
| #4 | -10.54% Apr 9, 2026 - Apr 17, 2026 | -16.77% Dec 4, 2024 - Dec 23, 2024 |
| #5 | -9.76% Oct 27, 2025 - Oct 30, 2025 | -16.19% Nov 7, 2024 - Dec 4, 2024 |
| #6 | -8.09% Apr 17, 2026 - Apr 22, 2026 | -13.97% Nov 26, 2025 - Dec 19, 2025 |
| #7 | -1.54% Dec 10, 2025 - Dec 12, 2025 | -10.63% Feb 17, 2026 - Feb 24, 2026 |
| #8 | -0.22% Dec 5, 2025 - Dec 9, 2025 | -6.45% Oct 25, 2024 - Oct 31, 2024 |
| #9 | N/A | -4.76% Oct 31, 2024 - Nov 4, 2024 |
| #10 | N/A | -3.57% May 28, 2026 - Jun 4, 2026 |
| #11 | N/A | -3.45% Nov 4, 2024 - Nov 6, 2024 |
| #12 | N/A | -1.89% Nov 24, 2025 - Nov 26, 2025 |
| #13 | N/A | -0.70% Jun 4, 2026 - Jun 5, 2026 |
Correlation
Correlation between MPLT and SEPN is 0.19 which considered as a very weak or no correlation - the stocks move independently of each other.
0.19
-101
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