MKSI vs INSM

Comparison between MKS Instruments Inc (MKSI, Company) and Insmed Inc (INSM, Company).

MKSI is from the Technology sector, while INSM is from the Healthcare sector.

5-Year PerformanceINSM has outperformed MKSI, delivering a return of +33.1% compared to +16.8%

MKSI vs INSM - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	MKSI(COMPANY)	INSM(COMPANY)
Market Cap	$24B	$24B
Max Drawdown	85.67%	98.65%
Sharpe Ratio	2.31	0.31
5Y Beta	2.53	0.77
Industry	Scientific & Technical Instruments	Biotechnology
P/E Ratio	72.74	-19.78
Forward P/E	10.36	16.37
PEG Ratio	1.65	1.09
Dividend Yield	0.28%	N/A
5Y Dividends CAGR	2.77%	N/A
5Y EPS CAGR	-7.80%	12.24%
Debt to Equity	144.01%	76.93%
Free Cash Flow Yield	1.69%	-3.88%
P/S Ratio	5.94	28.42
P/B Ratio	8.46	33.77

Market Cap

Winner

MKSI

$24B

INSM

$24B

Max Drawdown

Winner

MKSI

85.67%

INSM

98.65%

Sharpe Ratio

Winner

MKSI

2.31

INSM

0.31

5Y Beta

MKSI

2.53

Winner

INSM

0.77

Industry

MKSI

Scientific & Technical Instruments

INSM

Biotechnology

P/E Ratio

MKSI

72.74

Winner

INSM

-19.78

Forward P/E

Winner

MKSI

10.36

INSM

16.37

PEG Ratio

MKSI

1.65

Winner

INSM

1.09

Dividend Yield

MKSI

0.28%

INSM

N/A

5Y Dividends CAGR

MKSI

2.77%

INSM

N/A

5Y EPS CAGR

MKSI

-7.80%

Winner

INSM

12.24%

Debt to Equity

MKSI

144.01%

Winner

INSM

76.93%

Free Cash Flow Yield

Winner

MKSI

1.69%

INSM

-3.88%

P/S Ratio

Winner

MKSI

5.94

INSM

28.42

P/B Ratio

Winner

MKSI

8.46

INSM

33.77

MKSI vs INSM - Historical Returns

Returns include dividend reinvestment.

Period	MKSI	INSM
1 month	-17.86%	+10.16%
3 months	+26.27%	-22.95%
6 months	+56.77%	-30.51%
1 year	+236.04%	+5.68%
5 years(CAGR)	+16.76%	+33.09%
10 years(CAGR)	+23.21%	+25.54%
Max(CAGR)	+11.46%	-1.58%

MKSI

-17.86%

Winner

INSM

+10.16%

Winner

MKSI

+26.27%

INSM

-22.95%

Winner

MKSI

+56.77%

INSM

-30.51%

Winner

MKSI

+236.04%

INSM

+5.68%

5Y(CAGR)

MKSI

+16.76%

Winner

INSM

+33.09%

10Y(CAGR)

MKSI

+23.21%

Winner

INSM

+25.54%

Max(CAGR)

Winner

MKSI

+11.46%

INSM

-1.58%

MKSI vs INSM - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	MKSI	INSM
2026	+105.53%	-38.67%
2025	+51.97%	+148.81%
2024	+5.36%	+130.59%
2023	+22.68%	+61.57%
2022	-51.89%	-28.97%
2021	+16.54%	-18.49%
2020	+35.47%	+40.70%
2019	+68.00%	+70.94%
2018	-33.59%	-59.58%
2017	+59.27%	+138.38%
2016	+69.39%	-23.26%
2015	+1.11%	+13.72%
2014	+25.09%	-9.74%
2013	+13.89%	+144.25%
2012	-6.11%	+112.38%
2011	+13.53%	-52.34%
2010	+37.41%	-18.08%
2009	+14.17%	+57.14%
2008	-20.65%	-43.67%
2007	-15.31%	-8.33%
2006	+21.73%	-58.69%
2005	-1.87%	-14.35%
2004	-35.77%	-27.43%
2003	+71.90%	+518.75%
2002	-39.84%	-88.60%
2001	+70.97%	+1.87%
2000	-53.91%	-78.95%
1999	+55.60%	N/A

MKSI vs INSM Drawdown Comparison

The maximum drawdown for MKSI was -85.67%, occurring on Oct 9, 2002. Recovery took 4198 trading sessions.

The maximum drawdown for INSM was -98.65%, occurring on Nov 25, 2011. Recovery took 6341 trading sessions.

The current MKSI drawdown is -22.34%. The current INSM drawdown is -48.62%.

Rank	MKSI	INSM
#1	-85.67% Mar 10, 2000 - Nov 15, 2016	-98.65% Aug 30, 2000 - Nov 17, 2025
#2	-69.20% Apr 5, 2021 - Jan 13, 2026	-56.54% Dec 1, 2025 - Jun 10, 2026
#3	-54.26% Mar 21, 2018 - Jul 23, 2020	-35.29% Jun 5, 2000 - Aug 3, 2000
#4	-27.10% Jun 30, 2026 - Jul 20, 2026	-28.69% Aug 3, 2000 - Aug 28, 2000
#5	-24.72% Jan 21, 2000 - Feb 8, 2000	-2.91% Jun 1, 2000 - Jun 5, 2000
#6	-23.04% Jun 8, 2017 - Sep 18, 2017	-2.36% Nov 19, 2025 - Nov 24, 2025
#7	-21.42% Jan 20, 2021 - Apr 1, 2021	-2.16% Nov 25, 2025 - Dec 1, 2025
#8	-20.06% Feb 17, 2026 - Apr 9, 2026	N/A
#9	-19.47% Aug 4, 2020 - Nov 11, 2020	N/A
#10	-17.48% Oct 31, 2017 - Feb 1, 2018	N/A
#11	-14.61% Feb 9, 2000 - Feb 24, 2000	N/A
#12	-14.20% Dec 31, 1999 - Jan 19, 2000	N/A
#13	-12.39% Nov 11, 1999 - Dec 7, 1999	N/A
#14	-11.04% Feb 1, 2018 - Feb 15, 2018	N/A
#15	-10.00% Jun 3, 2026 - Jun 11, 2026	N/A