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INSM vs SPY

Comparison between Insmed Inc (INSM, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).

5-Year PerformanceINSM has outperformed SPY, delivering a return of +30.2% compared to +13.0%

INSM vs SPY - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap / Net Assets
INSM
$21B
Winner
SPY
$784B
Expense Ratio
INSM
N/A
SPY
0.09%
Max Drawdown
INSM
98.65%
Winner
SPY
56.47%
Sharpe Ratio
INSM
0.19
Winner
SPY
1.54
5Y Beta
Winner
INSM
0.77
SPY
1.00
Industry
INSM
Biotechnology
SPY
N/A
P/E Ratio
Winner
INSM
-17.25
SPY
27.62
Forward P/E
Winner
INSM
16.37
SPY
21.11
PEG Ratio
INSM
1.09
SPY
N/A
5Y Dividends CAGR
INSM
N/A
SPY
6.00%
5Y EPS CAGR
INSM
12.24%
Winner
SPY
25.30%
Debt to Equity
INSM
76.93%
Winner
SPY
31.11%
Free Cash Flow Yield
INSM
-4.44%
SPY
N/A
P/S Ratio
INSM
26.08
Winner
SPY
3.49
P/B Ratio
INSM
29.46
Winner
SPY
5.30

INSM vs SPY - Historical Returns

Returns include dividend reinvestment.

1M
INSM
-2.62%
Winner
SPY
-1.41%
3M
INSM
-25.64%
Winner
SPY
+12.54%
6M
INSM
-41.69%
Winner
SPY
+6.77%
1Y
INSM
-2.30%
Winner
SPY
+22.18%
5Y(CAGR)
Winner
INSM
+30.22%
SPY
+13.04%
10Y(CAGR)
Winner
INSM
+26.84%
SPY
+15.54%
Max(CAGR)
INSM
-1.77%
Winner
SPY
+8.44%

INSM vs SPY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

YearINSMSPY
2026-41.59%+7.90%
2025+148.81%+18.00%
2024+130.59%+25.59%
2023+61.57%+26.72%
2022-28.97%-18.64%
2021-18.49%+30.52%
2020+40.70%+17.28%
2019+70.94%+31.09%
2018-59.58%-5.24%
2017+138.38%+20.78%
2016-23.26%+13.59%
2015+13.72%+1.31%
2014-9.74%+14.56%
2013+144.25%+29.00%
2012+112.38%+14.17%
2011-52.34%+0.85%
2010-18.08%+13.14%
2009+57.14%+22.67%
2008-43.67%-36.25%
2007-8.33%+5.32%
2006-58.69%+13.85%
2005-14.35%+5.32%
2004-27.43%+10.75%
2003+518.75%+24.18%
2002-88.60%-22.42%
2001+1.87%-10.13%
2000-78.95%-8.84%
1999N/A+8.61%

INSM vs SPY Drawdown Comparison

The maximum drawdown for INSM was -98.65%, occurring on Nov 25, 2011. Recovery took 6341 trading sessions.

The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.

The current INSM drawdown is -51.06%. The current SPY drawdown is -3.22%.

RankINSMSPY
#1-98.65%
Aug 30, 2000 - Nov 17, 2025		-55.20%
Oct 9, 2007 - Aug 16, 2012
#2-56.54%
Dec 1, 2025 - Jun 10, 2026		-47.50%
Mar 24, 2000 - Oct 26, 2006
#3-35.29%
Jun 5, 2000 - Aug 3, 2000		-33.70%
Feb 19, 2020 - Aug 10, 2020
#4-28.69%
Aug 3, 2000 - Aug 28, 2000		-24.50%
Jan 3, 2022 - Dec 13, 2023
#5-2.91%
Jun 1, 2000 - Jun 5, 2000		-19.34%
Sep 20, 2018 - Apr 12, 2019
#6-2.36%
Nov 19, 2025 - Nov 24, 2025		-18.76%
Feb 19, 2025 - Jun 26, 2025
#7-2.16%
Nov 25, 2025 - Dec 1, 2025		-13.02%
Jul 20, 2015 - Apr 18, 2016
#8N/A-10.10%
Jan 26, 2018 - Aug 6, 2018
#9N/A-9.44%
Sep 2, 2020 - Nov 11, 2020
#10N/A-9.30%
Jan 19, 2000 - Mar 17, 2000
#11N/A-9.05%
Jul 19, 2007 - Oct 5, 2007
#12N/A-8.88%
Jan 27, 2026 - Apr 14, 2026
#13N/A-8.41%
Jul 16, 2024 - Sep 19, 2024
#14N/A-7.35%
Sep 14, 2012 - Jan 2, 2013
#15N/A-7.27%
Sep 18, 2014 - Oct 31, 2014

Correlation

Correlation between INSM and SPY is 0.61 which considered as a moderate positive correlation - the stocks show some tendency to move together.

0.61
-101

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