INSM vs SPY
Comparison between Insmed Inc (INSM, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).
5-Year PerformanceINSM has outperformed SPY, delivering a return of +25.5% compared to +13.3%
INSM vs SPY - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap / Net Assets
INSM
$29B
Winner
SPY
$652B
Expense Ratio
INSM
N/A
SPY
0.09%
Max Drawdown
INSM
98.65%
Winner
SPY
56.47%
Sharpe Ratio
INSM
0.91
Winner
SPY
2.07
5Y Beta
Winner
INSM
0.69
SPY
1.00
Industry
INSM
Biotechnology
SPY
N/A
P/E Ratio
Winner
INSM
-22.08
SPY
28.24
Forward P/E
Winner
INSM
16.37
SPY
21.85
PEG Ratio
INSM
-1.49
SPY
N/A
5Y Dividends CAGR
INSM
N/A
SPY
5.43%
5Y EPS CAGR
INSM
15.90%
Winner
SPY
25.79%
Debt to Equity
INSM
73.20%
Winner
SPY
22.35%
Free Cash Flow Yield
INSM
-3.29%
SPY
N/A
P/S Ratio
INSM
48.80
Winner
SPY
3.55
P/B Ratio
INSM
40.86
Winner
SPY
5.29
INSM vs SPY - Historical Returns
Returns include dividend reinvestment.
1M
INSM
-36.73%
Winner
SPY
+9.11%
3M
INSM
-32.23%
Winner
SPY
+6.59%
6M
INSM
-46.57%
Winner
SPY
+10.56%
1Y
Winner
INSM
+54.43%
SPY
+32.04%
5Y(CAGR)
Winner
INSM
+25.47%
SPY
+13.35%
10Y(CAGR)
Winner
INSM
+24.08%
SPY
+15.49%
Max(CAGR)
INSM
-1.86%
Winner
SPY
+8.50%
INSM vs SPY - Annual Returns (1999 - 2026)
Returns include dividend reinvestment.
| Year | INSM | SPY |
|---|---|---|
| 2026 | -42.78% | +8.27% |
| 2025 | +148.81% | +18.00% |
| 2024 | +130.59% | +25.59% |
| 2023 | +61.57% | +26.72% |
| 2022 | -28.97% | -18.64% |
| 2021 | -18.49% | +30.52% |
| 2020 | +40.70% | +17.28% |
| 2019 | +70.94% | +31.09% |
| 2018 | -59.58% | -5.24% |
| 2017 | +138.38% | +20.78% |
| 2016 | -23.26% | +13.59% |
| 2015 | +13.72% | +1.31% |
| 2014 | -9.74% | +14.56% |
| 2013 | +144.25% | +29.00% |
| 2012 | +112.38% | +14.17% |
| 2011 | -52.34% | +0.85% |
| 2010 | -18.08% | +13.14% |
| 2009 | +57.14% | +22.67% |
| 2008 | -43.67% | -36.25% |
| 2007 | -8.33% | +5.32% |
| 2006 | -58.69% | +13.85% |
| 2005 | -14.35% | +5.32% |
| 2004 | -27.43% | +10.75% |
| 2003 | +518.75% | +24.18% |
| 2002 | -88.60% | -22.42% |
| 2001 | +1.87% | -10.13% |
| 2000 | -78.95% | -8.84% |
| 1999 | N/A | +8.61% |
INSM vs SPY Drawdown Comparison
The maximum drawdown for INSM was -98.65%, occurring on Nov 25, 2011. Recovery took 6341 trading sessions.
The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.
The current INSM drawdown is -52.06%.
| Rank | INSM | SPY |
|---|---|---|
| #1 | -98.65% Aug 30, 2000 - Nov 17, 2025 | -55.20% Oct 9, 2007 - Aug 16, 2012 |
| #2 | -52.06% Dec 1, 2025 - May 8, 2026 | -47.50% Mar 24, 2000 - Oct 26, 2006 |
| #3 | -35.29% Jun 5, 2000 - Aug 3, 2000 | -33.70% Feb 19, 2020 - Aug 10, 2020 |
| #4 | -28.69% Aug 3, 2000 - Aug 28, 2000 | -24.50% Jan 3, 2022 - Dec 13, 2023 |
| #5 | -2.91% Jun 1, 2000 - Jun 5, 2000 | -19.34% Sep 20, 2018 - Apr 12, 2019 |
| #6 | -2.36% Nov 19, 2025 - Nov 24, 2025 | -18.76% Feb 19, 2025 - Jun 26, 2025 |
| #7 | -2.16% Nov 25, 2025 - Dec 1, 2025 | -13.02% Jul 20, 2015 - Apr 18, 2016 |
| #8 | N/A | -10.10% Jan 26, 2018 - Aug 6, 2018 |
| #9 | N/A | -9.44% Sep 2, 2020 - Nov 11, 2020 |
| #10 | N/A | -9.30% Jan 19, 2000 - Mar 17, 2000 |
| #11 | N/A | -9.05% Jul 19, 2007 - Oct 5, 2007 |
| #12 | N/A | -8.88% Jan 27, 2026 - Apr 14, 2026 |
| #13 | N/A | -8.41% Jul 16, 2024 - Sep 19, 2024 |
| #14 | N/A | -7.35% Sep 14, 2012 - Jan 2, 2013 |
| #15 | N/A | -7.27% Sep 18, 2014 - Oct 31, 2014 |
Correlation
Correlation between INSM and SPY is 0.60 which considered as a moderate positive correlation - the stocks show some tendency to move together.
0.60
-101
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