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MGNX vs SPY

Comparison between Macrogenics Inc (MGNX, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).

5-Year PerformanceSPY has outperformed MGNX, delivering a return of +13.4% compared to -28.6%

MGNX vs SPY - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap / Net Assets
MGNX
$246M
Winner
SPY
$784B
Expense Ratio
MGNX
N/A
SPY
0.09%
Max Drawdown
MGNX
97.36%
Winner
SPY
56.47%
Sharpe Ratio
MGNX
1.30
Winner
SPY
1.56
5Y Beta
MGNX
1.53
Winner
SPY
1.00
Industry
MGNX
Biotechnology
SPY
N/A
P/E Ratio
Winner
MGNX
-3.49
SPY
28.29
Forward P/E
MGNX
60.98
Winner
SPY
21.75
PEG Ratio
MGNX
-0.14
SPY
N/A
5Y Dividends CAGR
MGNX
N/A
SPY
5.43%
5Y EPS CAGR
MGNX
-14.38%
Winner
SPY
25.98%
Debt to Equity
Winner
MGNX
0.00%
SPY
30.79%
Free Cash Flow Yield
MGNX
-29.14%
SPY
N/A
P/S Ratio
Winner
MGNX
1.62
SPY
3.79
P/B Ratio
MGNX
11.60
Winner
SPY
5.67

MGNX vs SPY - Historical Returns

Returns include dividend reinvestment.

1M
Winner
MGNX
+12.50%
SPY
+0.48%
3M
Winner
MGNX
+26.92%
SPY
+11.67%
6M
Winner
MGNX
+182.86%
SPY
+9.42%
1Y
Winner
MGNX
+155.48%
SPY
+24.27%
5Y(CAGR)
MGNX
-28.58%
Winner
SPY
+13.36%
10Y(CAGR)
MGNX
-17.27%
Winner
SPY
+15.42%
Max(CAGR)
MGNX
-13.53%
Winner
SPY
+8.49%

MGNX vs SPY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

YearMGNXSPY
2026+145.96%+8.88%
2025-51.21%+18.00%
2024-68.07%+25.59%
2023+51.26%+26.72%
2022-60.30%-18.64%
2021-27.70%+30.52%
2020+112.06%+17.28%
2019-14.06%+31.09%
2018-34.60%-5.24%
2017-4.14%+20.78%
2016-30.50%+13.59%
2015-11.97%+1.31%
2014+21.64%+14.56%
2013+9.76%+29.00%
2012N/A+14.17%
2011N/A+0.85%
2010N/A+13.14%
2009N/A+22.67%
2008N/A-36.25%
2007N/A+5.32%
2006N/A+13.85%
2005N/A+5.32%
2004N/A+10.75%
2003N/A+24.18%
2002N/A-22.42%
2001N/A-10.13%
2000N/A-8.84%
1999N/A+8.61%

MGNX vs SPY Drawdown Comparison

The maximum drawdown for MGNX was -97.36%, occurring on Apr 4, 2025. This drawdown has not yet recovered.

The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.

The current MGNX drawdown is -90.15%. The current SPY drawdown is -2.35%.

RankMGNXSPY
#1-97.36%
Jan 17, 2014 - Apr 4, 2025		-55.20%
Oct 9, 2007 - Aug 16, 2012
#2-23.38%
Nov 13, 2013 - Jan 2, 2014		-47.50%
Mar 24, 2000 - Oct 26, 2006
#3-7.46%
Oct 24, 2013 - Nov 13, 2013		-33.70%
Feb 19, 2020 - Aug 10, 2020
#4-4.18%
Oct 11, 2013 - Oct 22, 2013		-24.50%
Jan 3, 2022 - Dec 13, 2023
#5-3.86%
Oct 22, 2013 - Oct 24, 2013		-19.34%
Sep 20, 2018 - Apr 12, 2019
#6-0.58%
Jan 3, 2014 - Jan 7, 2014		-18.76%
Feb 19, 2025 - Jun 26, 2025
#7-0.32%
Jan 14, 2014 - Jan 16, 2014		-13.02%
Jul 20, 2015 - Apr 18, 2016
#8-0.08%
Jan 10, 2014 - Jan 14, 2014		-10.10%
Jan 26, 2018 - Aug 6, 2018
#9N/A-9.44%
Sep 2, 2020 - Nov 11, 2020
#10N/A-9.30%
Jan 19, 2000 - Mar 17, 2000
#11N/A-9.05%
Jul 19, 2007 - Oct 5, 2007
#12N/A-8.88%
Jan 27, 2026 - Apr 14, 2026
#13N/A-8.41%
Jul 16, 2024 - Sep 19, 2024
#14N/A-7.35%
Sep 14, 2012 - Jan 2, 2013
#15N/A-7.27%
Sep 18, 2014 - Oct 31, 2014

Correlation

Correlation between MGNX and SPY is -0.74 which considered as a strong negative correlation - the stocks tend to move in opposite directions.

-0.74
-101

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