MEDP vs AXSM

Comparison between Medpace Holdings Inc (MEDP, Company) and Axsome Therapeutics Inc (AXSM, Company).

Both MEDP and AXSM are from the Healthcare sector.

5-Year PerformanceAXSM has outperformed MEDP, delivering a return of +31.4% compared to +21.5%

MEDP vs AXSM - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	MEDP(COMPANY)	AXSM(COMPANY)
Market Cap	$12B	$12B
Max Drawdown	42.87%	86.65%
Sharpe Ratio	0.68	1.93
5Y Beta	1.07	0.69
Industry	Diagnostics & Research	Biotechnology
P/E Ratio	26.06	-63.29
Forward P/E	25.19	333.33
PEG Ratio	1.34	N/A
5Y EPS CAGR	29.42%	6.89%
Debt to Equity	0.00%	344.13%
Free Cash Flow Yield	5.87%	-0.59%

Market Cap

Winner

MEDP

$12B

AXSM

$12B

Max Drawdown

Winner

MEDP

42.87%

AXSM

86.65%

Sharpe Ratio

MEDP

0.68

Winner

AXSM

1.93

5Y Beta

MEDP

1.07

Winner

AXSM

0.69

Industry

MEDP

Diagnostics & Research

AXSM

Biotechnology

P/E Ratio

MEDP

26.06

Winner

AXSM

-63.29

Forward P/E

Winner

MEDP

25.19

AXSM

333.33

PEG Ratio

MEDP

1.34

AXSM

N/A

5Y EPS CAGR

Winner

MEDP

29.42%

AXSM

6.89%

Debt to Equity

Winner

MEDP

0.00%

AXSM

344.13%

Free Cash Flow Yield

Winner

MEDP

5.87%

AXSM

-0.59%

MEDP vs AXSM - Historical Returns

Returns include dividend reinvestment.

Period	MEDP	AXSM
1 month	-15.46%	+31.96%
3 months	-1.00%	+29.86%
6 months	-28.34%	+71.27%
1 year	+36.63%	+122.69%
5 years(CAGR)	+21.47%	+31.42%
10 years(CAGR)	+32.23%	+36.29%
Max(CAGR)	+32.23%	+36.92%

MEDP

-15.46%

Winner

AXSM

+31.96%

MEDP

-1.00%

Winner

AXSM

+29.86%

MEDP

-28.34%

Winner

AXSM

+71.27%

MEDP

+36.63%

Winner

AXSM

+122.69%

5Y(CAGR)

MEDP

+21.47%

Winner

AXSM

+31.42%

10Y(CAGR)

MEDP

+32.23%

Winner

AXSM

+36.29%

Max(CAGR)

MEDP

+32.23%

Winner

AXSM

+36.92%

MEDP vs AXSM - Annual Returns (2015 - 2026)

Returns include dividend reinvestment.

Year	MEDP	AXSM
2026	-25.79%	+31.69%
2025	+67.78%	+109.16%
2024	+8.72%	+9.80%
2023	+47.17%	+8.55%
2022	-0.89%	+103.89%
2021	+61.91%	-53.61%
2020	+67.77%	-19.58%
2019	+60.42%	+3756.72%
2018	+42.51%	-48.49%
2017	+0.97%	-13.18%
2016	+29.79%	-44.63%
2015	N/A	+6.06%

MEDP vs AXSM Drawdown Comparison

The maximum drawdown for MEDP was -42.87%, occurring on Apr 27, 2022. Recovery took 264 trading sessions.

The maximum drawdown for AXSM was -86.65%, occurring on Dec 27, 2018. Recovery took 809 trading sessions.

The current MEDP drawdown is -31.72%.

Rank	MEDP	AXSM
#1	-42.87% Dec 27, 2021 - Jan 13, 2023	-86.65% Jan 5, 2016 - Mar 25, 2019
#2	-41.43% Dec 6, 2016 - Dec 19, 2017	-81.26% Dec 26, 2019 - Jan 30, 2025
#3	-39.47% Feb 25, 2020 - Jul 15, 2020	-42.70% Sep 16, 2019 - Nov 19, 2019
#4	-39.38% Jul 16, 2024 - Jul 22, 2025	-30.56% Feb 21, 2025 - Nov 6, 2025
#5	-36.61% Jan 21, 2026 - Apr 23, 2026	-18.50% Jan 21, 2026 - Apr 30, 2026
#6	-27.23% Jan 23, 2023 - Jun 30, 2023	-17.63% Mar 25, 2019 - Apr 25, 2019
#7	-27.15% Feb 25, 2019 - Jul 30, 2019	-17.48% Jul 26, 2019 - Sep 16, 2019
#8	-26.31% Sep 18, 2018 - Dec 3, 2018	-17.26% May 28, 2019 - Jun 20, 2019
#9	-26.07% Dec 3, 2018 - Jan 31, 2019	-11.38% Jun 20, 2019 - Jun 27, 2019
#10	-19.22% Sep 13, 2023 - Nov 14, 2023	-10.33% Nov 24, 2015 - Dec 29, 2015
#11	-18.41% Sep 17, 2019 - Jan 14, 2020	-9.37% Jul 2, 2019 - Jul 26, 2019
#12	-18.36% Apr 26, 2021 - Sep 3, 2021	-8.83% Dec 4, 2019 - Dec 10, 2019
#13	-18.12% Sep 2, 2020 - Dec 1, 2020	-8.26% Dec 31, 2025 - Jan 20, 2026
#14	-17.99% Feb 26, 2018 - May 7, 2018	-7.23% Feb 5, 2025 - Feb 10, 2025
#15	-12.03% Nov 24, 2025 - Jan 21, 2026	-6.21% Nov 28, 2025 - Dec 19, 2025