MDXG vs RGLS

Comparison between Mimedx Group Inc (MDXG, Company) and Regulus Therapeutics Inc (RGLS, Company).

5-Year PerformanceRGLS has outperformed MDXG, delivering a return of +0.4% compared to -20.1%

MDXG vs RGLS - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	MDXG(COMPANY)	RGLS(COMPANY)
Market Cap	$542M	$540M
Max Drawdown	93.83%	99.97%
Sharpe Ratio	-1.20	1.24
5Y Beta	0.75	N/A
Industry	Biotechnology	N/A
P/E Ratio	17.52	-10.76
Forward P/E	19.53	N/A
PEG Ratio	2.88	N/A
Debt to Equity	7.24%	0.00%
Free Cash Flow Yield	13.02%	-8.08%
P/S Ratio	1.42	0.57
P/B Ratio	2.27	7.82

Market Cap

Winner

MDXG

$542M

RGLS

$540M

Max Drawdown

Winner

MDXG

93.83%

RGLS

99.97%

Sharpe Ratio

MDXG

-1.20

Winner

RGLS

1.24

5Y Beta

MDXG

0.75

RGLS

N/A

Industry

MDXG

Biotechnology

RGLS

N/A

P/E Ratio

MDXG

17.52

Winner

RGLS

-10.76

Forward P/E

MDXG

19.53

RGLS

N/A

PEG Ratio

MDXG

2.88

RGLS

N/A

Debt to Equity

MDXG

7.24%

Winner

RGLS

0.00%

Free Cash Flow Yield

Winner

MDXG

13.02%

RGLS

-8.08%

P/S Ratio

MDXG

1.42

Winner

RGLS

0.57

P/B Ratio

Winner

MDXG

2.27

RGLS

7.82

MDXG vs RGLS - Historical Returns

Returns include dividend reinvestment.

Period	MDXG	RGLS
1 month	+1.69%	+3.42%
3 months	-17.81%	+527.69%
6 months	-50.14%	+429.87%
1 year	-41.18%	+281.31%
5 years(CAGR)	-20.06%	+0.40%
10 years(CAGR)	-7.43%	-39.42%
Max(CAGR)	+13.95%	-27.95%

MDXG

+1.69%

Winner

RGLS

+3.42%

MDXG

-17.81%

Winner

RGLS

+527.69%

MDXG

-50.14%

Winner

RGLS

+429.87%

MDXG

-41.18%

Winner

RGLS

+281.31%

5Y(CAGR)

MDXG

-20.06%

Winner

RGLS

+0.40%

10Y(CAGR)

Winner

MDXG

-7.43%

RGLS

-39.42%

Max(CAGR)

Winner

MDXG

+13.95%

RGLS

-27.95%

MDXG vs RGLS - Annual Returns (2007 - 2026)

Returns include dividend reinvestment.

Year	MDXG	RGLS
2026	-44.44%	N/A
2025	-27.05%	+423.08%
2024	+22.24%	+20.61%
2023	+195.29%	-5.88%
2022	-55.66%	-58.23%
2021	-34.06%	-75.77%
2020	+24.38%	+33.66%
2019	+311.96%	-19.82%
2018	-86.21%	-93.14%
2017	+43.95%	-54.78%
2016	-1.12%	-73.75%
2015	-3.80%	-49.27%
2014	+36.45%	+117.93%
2013	+121.27%	+15.65%
2012	+207.20%	+43.84%
2011	-16.30%	N/A
2010	+80.00%	N/A
2009	-83.41%	N/A
2008	+1325.79%	N/A
2007	+0.00%	N/A

MDXG vs RGLS Drawdown Comparison

The maximum drawdown for MDXG was -93.83%, occurring on Mar 24, 2009. Recovery took 1279 trading sessions.

The maximum drawdown for RGLS was -99.97%, occurring on Mar 27, 2023. This drawdown has not yet recovered.

The current MDXG drawdown is -79.96%. The current RGLS drawdown is -99.69%.

Rank	MDXG	RGLS
#1	-93.83% Mar 31, 2008 - Apr 29, 2013	-99.97% Nov 7, 2014 - Mar 27, 2023
#2	-93.60% Jan 29, 2018 - Dec 7, 2018	-53.26% Jul 11, 2013 - Oct 22, 2014
#3	-48.65% Jul 17, 2015 - May 3, 2017	-25.98% Jan 2, 2013 - Mar 13, 2013
#4	-47.65% Jun 25, 2013 - Dec 12, 2013	-16.39% Mar 28, 2013 - May 29, 2013
#5	-41.76% Dec 31, 2013 - Oct 15, 2014	-15.76% Oct 25, 2012 - Dec 19, 2012
#6	-37.31% Aug 22, 2017 - Jan 29, 2018	-10.59% Jun 21, 2013 - Jul 2, 2013
#7	-32.01% Dec 19, 2014 - Jul 13, 2015	-6.27% Nov 4, 2014 - Nov 7, 2014
#8	-31.32% Feb 11, 2008 - Mar 27, 2008	-5.25% Oct 9, 2012 - Oct 18, 2012
#9	-12.87% May 16, 2017 - Jun 21, 2017	-4.66% Oct 27, 2014 - Oct 31, 2014
#10	-8.66% Jun 23, 2017 - Aug 14, 2017	-4.43% Mar 20, 2013 - Mar 22, 2013
#11	-7.32% May 22, 2013 - Jun 25, 2013	-1.99% Jun 13, 2013 - Jun 20, 2013
#12	-6.13% Dec 9, 2014 - Dec 18, 2014	-1.62% Jun 3, 2013 - Jun 10, 2013
#13	-6.07% Apr 30, 2013 - May 16, 2013	-0.96% Dec 20, 2012 - Dec 27, 2012
#14	-5.80% Oct 15, 2014 - Oct 22, 2014	-0.74% Mar 15, 2013 - Mar 20, 2013
#15	-4.84% Aug 16, 2017 - Aug 22, 2017	-0.31% Mar 13, 2013 - Mar 15, 2013