MDGL vs QXO

Comparison between Madrigal Pharmaceuticals Inc (MDGL, Company) and QXO Inc (QXO, Company).

MDGL is from the Healthcare sector, while QXO is from the Industrials sector.

5-Year PerformanceMDGL has outperformed QXO, delivering a return of +39.8% compared to -25.4%

MDGL vs QXO - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	MDGL(COMPANY)	QXO(COMPANY)
Market Cap	$12B	$12B
Max Drawdown	98.40%	95.44%
Sharpe Ratio	1.31	-0.22
5Y Beta	0.74	1.19
Industry	Biotechnology	Industrial Distribution
P/E Ratio	-37.84	-20.60
Forward P/E	666.67	45.45
5Y Dividends CAGR	N/A	133.49%
5Y EPS CAGR	23.26%	N/A
Debt to Equity	62.62%	30.09%
Free Cash Flow Yield	-2.30%	4.30%

Market Cap

Winner

MDGL

$12B

QXO

$12B

Max Drawdown

MDGL

98.40%

Winner

QXO

95.44%

Sharpe Ratio

Winner

MDGL

1.31

QXO

-0.22

5Y Beta

Winner

MDGL

0.74

QXO

1.19

Industry

MDGL

Biotechnology

QXO

Industrial Distribution

P/E Ratio

Winner

MDGL

-37.84

QXO

-20.60

Forward P/E

MDGL

666.67

Winner

QXO

45.45

5Y Dividends CAGR

MDGL

N/A

QXO

133.49%

5Y EPS CAGR

MDGL

23.26%

QXO

N/A

Debt to Equity

MDGL

62.62%

Winner

QXO

30.09%

Free Cash Flow Yield

MDGL

-2.30%

Winner

QXO

4.30%

MDGL vs QXO - Historical Returns

Returns include dividend reinvestment.

Period	MDGL	QXO
1 month	+16.61%	-0.67%
3 months	-3.44%	-14.82%
6 months	-11.07%	-17.80%
1 year	+75.95%	-24.92%
5 years(CAGR)	+39.78%	-25.44%
10 years(CAGR)	+48.21%	+7.56%
Max(CAGR)	+2.65%	+39.19%

Winner

MDGL

+16.61%

QXO

-0.67%

Winner

MDGL

-3.44%

QXO

-14.82%

Winner

MDGL

-11.07%

QXO

-17.80%

Winner

MDGL

+75.95%

QXO

-24.92%

5Y(CAGR)

Winner

MDGL

+39.78%

QXO

-25.44%

10Y(CAGR)

Winner

MDGL

+48.21%

QXO

+7.56%

Max(CAGR)

MDGL

+2.65%

Winner

QXO

+39.19%

MDGL vs QXO - Annual Returns (2007 - 2026)

Returns include dividend reinvestment.

Year	MDGL	QXO
2026	-11.07%	-17.80%
2025	+85.59%	+25.50%
2024	+36.02%	-85.24%
2023	-18.93%	+520.26%
2022	+222.07%	-38.91%
2021	-22.80%	+57.21%
2020	+22.60%	-19.61%
2019	-18.06%	+92.19%
2018	+15.71%	-43.00%
2017	+475.13%	+43.82%
2016	+28.97%	+12.42%
2015	-87.74%	+1027.22%
2014	-49.62%	+69.31%
2013	-45.64%	-41.67%
2012	+84.46%	+275.00%
2011	-24.56%	N/A
2010	+10.87%	N/A
2009	-17.99%	N/A
2008	-3.62%	N/A
2007	-26.29%	N/A

MDGL vs QXO Drawdown Comparison

The maximum drawdown for MDGL was -98.40%, occurring on Feb 11, 2016. Recovery took 3162 trading sessions.

The maximum drawdown for QXO was -95.44%, occurring on Aug 14, 2024. This drawdown has not yet recovered.

The current MDGL drawdown is -12.40%. The current QXO drawdown is -93.12%.

Rank	MDGL	QXO
#1	-98.40% Jan 28, 2013 - Aug 22, 2025	-95.44% Jun 10, 2024 - Aug 14, 2024
#2	-87.64% Oct 5, 2007 - Jan 22, 2013	-87.50% May 7, 2012 - Feb 5, 2015
#3	-51.43% Jun 4, 2007 - Oct 4, 2007	-82.93% Jul 6, 2021 - Dec 27, 2023
#4	-29.36% Dec 22, 2025 - Mar 3, 2026	-75.70% Mar 3, 2015 - Aug 4, 2020
#5	-18.88% Feb 9, 2007 - Jun 4, 2007	-57.78% Aug 4, 2020 - Jan 25, 2021
#6	-10.10% Sep 30, 2025 - Nov 5, 2025	-44.86% Jan 5, 2024 - Jun 6, 2024
#7	-9.42% Nov 26, 2025 - Dec 22, 2025	-44.44% Mar 30, 2012 - Apr 25, 2012
#8	-8.01% Sep 8, 2025 - Sep 30, 2025	-27.24% Feb 25, 2021 - Apr 1, 2021
#9	-4.91% Nov 11, 2025 - Nov 17, 2025	-25.27% Apr 1, 2021 - Jun 21, 2021
#10	-4.32% Jan 23, 2013 - Jan 25, 2013	-22.67% Jan 26, 2021 - Feb 16, 2021
#11	-3.02% Nov 18, 2025 - Nov 24, 2025	-21.80% Feb 5, 2015 - Mar 3, 2015
#12	-1.52% Aug 29, 2025 - Sep 8, 2025	-17.20% Mar 27, 2012 - Mar 29, 2012
#13	-0.59% Aug 22, 2025 - Aug 26, 2025	-10.93% Dec 29, 2023 - Jan 4, 2024
#14	N/A	-10.01% Feb 22, 2021 - Feb 25, 2021
#15	N/A	-9.96% Apr 25, 2012 - Apr 27, 2012