MDGL vs MEDP

Comparison between Madrigal Pharmaceuticals Inc (MDGL, Company) and Medpace Holdings Inc (MEDP, Company).

Both MDGL and MEDP are from the Healthcare sector.

5-Year PerformanceMDGL has outperformed MEDP, delivering a return of +36.9% compared to +21.8%

MDGL vs MEDP - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	MDGL(COMPANY)	MEDP(COMPANY)
Market Cap	$12B	$12B
Max Drawdown	98.40%	42.87%
Sharpe Ratio	1.36	0.79
5Y Beta	0.73	1.05
Industry	Biotechnology	Diagnostics & Research
P/E Ratio	-38.82	26.32
Forward P/E	666.67	26.81
PEG Ratio	0.00	1.35
5Y EPS CAGR	23.26%	29.42%
Debt to Equity	62.62%	0.00%
Free Cash Flow Yield	-2.25%	5.82%
P/S Ratio	10.69	4.72
P/B Ratio	22.39	20.43

Market Cap

MDGL

$12B

Winner

MEDP

$12B

Max Drawdown

MDGL

98.40%

Winner

MEDP

42.87%

Sharpe Ratio

Winner

MDGL

1.36

MEDP

0.79

5Y Beta

Winner

MDGL

0.73

MEDP

1.05

Industry

MDGL

Biotechnology

MEDP

Diagnostics & Research

P/E Ratio

Winner

MDGL

-38.82

MEDP

26.32

Forward P/E

MDGL

666.67

Winner

MEDP

26.81

PEG Ratio

Winner

MDGL

0.00

MEDP

1.35

5Y EPS CAGR

MDGL

23.26%

Winner

MEDP

29.42%

Debt to Equity

MDGL

62.62%

Winner

MEDP

0.00%

Free Cash Flow Yield

MDGL

-2.25%

Winner

MEDP

5.82%

P/S Ratio

MDGL

10.69

Winner

MEDP

4.72

P/B Ratio

MDGL

22.39

Winner

MEDP

20.43

MDGL vs MEDP - Historical Returns

Returns include dividend reinvestment.

Period	MDGL	MEDP
1 month	-3.08%	+5.56%
3 months	+10.84%	-3.22%
6 months	-15.65%	-17.13%
1 year	+77.67%	+54.73%
5 years(CAGR)	+36.93%	+21.83%
10 years(CAGR)	+43.49%	+32.93%
Max(CAGR)	+2.23%	+32.93%

MDGL

-3.08%

Winner

MEDP

+5.56%

Winner

MDGL

+10.84%

MEDP

-3.22%

Winner

MDGL

-15.65%

MEDP

-17.13%

Winner

MDGL

+77.67%

MEDP

+54.73%

5Y(CAGR)

Winner

MDGL

+36.93%

MEDP

+21.83%

10Y(CAGR)

Winner

MDGL

+43.49%

MEDP

+32.93%

Max(CAGR)

MDGL

+2.23%

Winner

MEDP

+32.93%

MDGL vs MEDP - Annual Returns (2007 - 2026)

Returns include dividend reinvestment.

Year	MDGL	MEDP
2026	-18.00%	-20.45%
2025	+85.59%	+67.78%
2024	+36.02%	+8.72%
2023	-18.93%	+47.17%
2022	+222.07%	-0.89%
2021	-22.80%	+61.91%
2020	+22.60%	+67.77%
2019	-18.06%	+60.42%
2018	+15.71%	+42.51%
2017	+475.13%	+0.97%
2016	+28.97%	+29.79%
2015	-87.74%	N/A
2014	-49.62%	N/A
2013	-45.64%	N/A
2012	+84.46%	N/A
2011	-24.56%	N/A
2010	+10.87%	N/A
2009	-17.99%	N/A
2008	-3.62%	N/A
2007	-26.29%	N/A

MDGL vs MEDP Drawdown Comparison

The maximum drawdown for MDGL was -98.40%, occurring on Feb 11, 2016. Recovery took 3162 trading sessions.

The maximum drawdown for MEDP was -42.87%, occurring on Apr 27, 2022. Recovery took 264 trading sessions.

The current MDGL drawdown is -19.22%. The current MEDP drawdown is -26.80%.

Rank	MDGL	MEDP
#1	-98.40% Jan 28, 2013 - Aug 22, 2025	-42.87% Dec 27, 2021 - Jan 13, 2023
#2	-87.64% Oct 5, 2007 - Jan 22, 2013	-41.43% Dec 6, 2016 - Dec 19, 2017
#3	-51.43% Jun 4, 2007 - Oct 4, 2007	-39.47% Feb 25, 2020 - Jul 15, 2020
#4	-29.36% Dec 22, 2025 - Mar 3, 2026	-39.38% Jul 16, 2024 - Jul 22, 2025
#5	-18.88% Feb 9, 2007 - Jun 4, 2007	-36.61% Jan 21, 2026 - Apr 23, 2026
#6	-10.10% Sep 30, 2025 - Nov 5, 2025	-27.23% Jan 23, 2023 - Jun 30, 2023
#7	-9.42% Nov 26, 2025 - Dec 22, 2025	-27.15% Feb 25, 2019 - Jul 30, 2019
#8	-8.01% Sep 8, 2025 - Sep 30, 2025	-26.31% Sep 18, 2018 - Dec 3, 2018
#9	-4.91% Nov 11, 2025 - Nov 17, 2025	-26.07% Dec 3, 2018 - Jan 31, 2019
#10	-4.32% Jan 23, 2013 - Jan 25, 2013	-19.22% Sep 13, 2023 - Nov 14, 2023
#11	-3.02% Nov 18, 2025 - Nov 24, 2025	-18.41% Sep 17, 2019 - Jan 14, 2020
#12	-1.52% Aug 29, 2025 - Sep 8, 2025	-18.36% Apr 26, 2021 - Sep 3, 2021
#13	-0.59% Aug 22, 2025 - Aug 26, 2025	-18.12% Sep 2, 2020 - Dec 1, 2020
#14	N/A	-17.99% Feb 26, 2018 - May 7, 2018
#15	N/A	-12.03% Nov 24, 2025 - Jan 21, 2026