MDGL vs COF-P-I

Comparison between Madrigal Pharmaceuticals Inc (MDGL, Company) and Capital One Financial Corp (COF-P-I, Company).

5-Year PerformanceMDGL has outperformed COF-P-I, delivering a return of +31.6% compared to -0.2%

MDGL vs COF-P-I - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	MDGL(COMPANY)	COF-P-I(COMPANY)
Market Cap	$12B	$12B
Max Drawdown	98.40%	47.15%
Sharpe Ratio	1.35	0.48
5Y Beta	0.73	0.23
Industry	Biotechnology	Other
P/E Ratio	-38.17	3.54
Forward P/E	666.67	N/A
5Y Dividends CAGR	N/A	4.56%
5Y EPS CAGR	23.26%	-1.70%
Debt to Equity	62.62%	0.96%
Free Cash Flow Yield	-2.29%	N/A

Market Cap

MDGL

$12B

Winner

COF-P-I

$12B

Max Drawdown

MDGL

98.40%

Winner

COF-P-I

47.15%

Sharpe Ratio

Winner

MDGL

1.35

COF-P-I

0.48

5Y Beta

MDGL

0.73

Winner

COF-P-I

0.23

Industry

MDGL

Biotechnology

COF-P-I

Other

P/E Ratio

Winner

MDGL

-38.17

COF-P-I

3.54

Forward P/E

MDGL

666.67

COF-P-I

N/A

5Y Dividends CAGR

MDGL

N/A

COF-P-I

4.56%

5Y EPS CAGR

Winner

MDGL

23.26%

COF-P-I

-1.70%

Debt to Equity

MDGL

62.62%

Winner

COF-P-I

0.96%

Free Cash Flow Yield

MDGL

-2.29%

COF-P-I

N/A

MDGL vs COF-P-I - Historical Returns

Returns include dividend reinvestment.

Period	MDGL	COF-P-I
1 month	-1.29%	+0.03%
3 months	+11.65%	-1.82%
6 months	+0.77%	+0.65%
1 year	+75.67%	+7.90%
5 years(CAGR)	+31.57%	-0.20%
10 years(CAGR)	+43.22%	N/A
Max(CAGR)	+2.57%	+1.65%

MDGL

-1.29%

Winner

COF-P-I

+0.03%

Winner

MDGL

+11.65%

COF-P-I

-1.82%

Winner

MDGL

+0.77%

COF-P-I

+0.65%

Winner

MDGL

+75.67%

COF-P-I

+7.90%

5Y(CAGR)

Winner

MDGL

+31.57%

COF-P-I

-0.20%

10Y(CAGR)

MDGL

+43.22%

COF-P-I

N/A

Max(CAGR)

Winner

MDGL

+2.57%

COF-P-I

+1.65%

MDGL vs COF-P-I - Annual Returns (2007 - 2026)

Returns include dividend reinvestment.

Year	MDGL	COF-P-I
2026	-12.63%	+0.61%
2025	+85.59%	+3.83%
2024	+36.02%	+8.52%
2023	-18.93%	+6.50%
2022	+222.07%	-28.20%
2021	-22.80%	+6.82%
2020	+22.60%	+10.62%
2019	-18.06%	+1.48%
2018	+15.71%	N/A
2017	+475.13%	N/A
2016	+28.97%	N/A
2015	-87.74%	N/A
2014	-49.62%	N/A
2013	-45.64%	N/A
2012	+84.46%	N/A
2011	-24.56%	N/A
2010	+10.87%	N/A
2009	-17.99%	N/A
2008	-3.62%	N/A
2007	-26.29%	N/A

MDGL vs COF-P-I Drawdown Comparison

The maximum drawdown for MDGL was -98.40%, occurring on Feb 11, 2016. Recovery took 3162 trading sessions.

The maximum drawdown for COF-P-I was -46.78%, occurring on Mar 18, 2020. Recovery took 116 trading sessions.

The current MDGL drawdown is -13.93%. The current COF-P-I drawdown is -6.61%.

Rank	MDGL	COF-P-I
#1	-98.40% Jan 28, 2013 - Aug 22, 2025	-46.78% Mar 4, 2020 - Aug 18, 2020
#2	-87.64% Oct 5, 2007 - Jan 22, 2013	-33.67% Dec 31, 2021 - Oct 20, 2023
#3	-51.43% Jun 4, 2007 - Oct 4, 2007	-6.36% Jan 20, 2021 - Apr 6, 2021
#4	-29.36% Dec 22, 2025 - Mar 3, 2026	-4.14% Aug 6, 2021 - Dec 29, 2021
#5	-18.88% Feb 9, 2007 - Jun 4, 2007	-3.57% Dec 31, 2020 - Jan 20, 2021
#6	-10.10% Sep 30, 2025 - Nov 5, 2025	-3.48% Feb 20, 2020 - Mar 4, 2020
#7	-9.42% Nov 26, 2025 - Dec 22, 2025	-2.95% Sep 6, 2019 - Oct 18, 2019
#8	-8.01% Sep 8, 2025 - Sep 30, 2025	-2.80% Oct 13, 2020 - Nov 9, 2020
#9	-4.91% Nov 11, 2025 - Nov 17, 2025	-2.54% Jun 30, 2021 - Aug 5, 2021
#10	-4.32% Jan 23, 2013 - Jan 25, 2013	-2.48% Sep 1, 2020 - Oct 5, 2020
#11	-3.02% Nov 18, 2025 - Nov 24, 2025	-2.45% Oct 25, 2019 - Dec 18, 2019
#12	-1.52% Aug 29, 2025 - Sep 8, 2025	-1.89% Apr 8, 2021 - May 24, 2021
#13	-0.59% Aug 22, 2025 - Aug 26, 2025	-1.05% Oct 6, 2020 - Oct 13, 2020
#14	N/A	-0.93% Jun 22, 2021 - Jun 30, 2021
#15	N/A	-0.71% Dec 20, 2019 - Jan 2, 2020