MDGL vs BMRN

Comparison between Madrigal Pharmaceuticals Inc (MDGL, Company) and Biomarin Pharmaceutical Inc (BMRN, Company).

Both MDGL and BMRN are from the Healthcare sector.

5-Year PerformanceMDGL has outperformed BMRN, delivering a return of +34.5% compared to -7.5%

MDGL vs BMRN - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	MDGL(COMPANY)	BMRN(COMPANY)
Market Cap	$11B	$11B
Max Drawdown	98.40%	90.58%
Sharpe Ratio	1.27	-0.04
5Y Beta	0.73	0.68
Industry	Biotechnology	Biotechnology
P/E Ratio	-34.67	40.22
Forward P/E	666.67	11.63
PEG Ratio	0.00	0.71
5Y EPS CAGR	23.26%	-20.33%
Debt to Equity	62.62%	23.02%
Free Cash Flow Yield	-2.52%	7.07%
P/S Ratio	9.68	3.45
P/B Ratio	20.25	1.80

Market Cap

Winner

MDGL

$11B

BMRN

$11B

Max Drawdown

MDGL

98.40%

Winner

BMRN

90.58%

Sharpe Ratio

Winner

MDGL

1.27

BMRN

-0.04

5Y Beta

MDGL

0.73

Winner

BMRN

0.68

Industry

MDGL

Biotechnology

BMRN

Biotechnology

P/E Ratio

Winner

MDGL

-34.67

BMRN

40.22

Forward P/E

MDGL

666.67

Winner

BMRN

11.63

PEG Ratio

Winner

MDGL

0.00

BMRN

0.71

5Y EPS CAGR

Winner

MDGL

23.26%

BMRN

-20.33%

Debt to Equity

MDGL

62.62%

Winner

BMRN

23.02%

Free Cash Flow Yield

MDGL

-2.52%

Winner

BMRN

7.07%

P/S Ratio

MDGL

9.68

Winner

BMRN

3.45

P/B Ratio

MDGL

20.25

Winner

BMRN

1.80

MDGL vs BMRN - Historical Returns

Returns include dividend reinvestment.

Period	MDGL	BMRN
1 month	-4.58%	+5.63%
3 months	+9.91%	-7.92%
6 months	-16.99%	+4.81%
1 year	+61.13%	-2.83%
5 years(CAGR)	+34.46%	-7.51%
10 years(CAGR)	+44.09%	-3.71%
Max(CAGR)	+2.09%	+4.94%

MDGL

-4.58%

Winner

BMRN

+5.63%

Winner

MDGL

+9.91%

BMRN

-7.92%

MDGL

-16.99%

Winner

BMRN

+4.81%

Winner

MDGL

+61.13%

BMRN

-2.83%

5Y(CAGR)

Winner

MDGL

+34.46%

BMRN

-7.51%

10Y(CAGR)

Winner

MDGL

+44.09%

BMRN

-3.71%

Max(CAGR)

MDGL

+2.09%

Winner

BMRN

+4.94%

MDGL vs BMRN - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	MDGL	BMRN
2026	-20.14%	-6.58%
2025	+85.59%	-10.62%
2024	+36.02%	-32.96%
2023	-18.93%	-4.16%
2022	+222.07%	+15.81%
2021	-22.80%	+2.38%
2020	+22.60%	+4.34%
2019	-18.06%	-0.48%
2018	+15.71%	-6.46%
2017	+475.13%	+3.88%
2016	+28.97%	-21.04%
2015	-87.74%	+13.66%
2014	-49.62%	+30.50%
2013	-45.64%	+35.50%
2012	+84.46%	+40.85%
2011	-24.56%	+29.20%
2010	+10.87%	+42.11%
2009	-17.99%	+6.57%
2008	-3.62%	-51.42%
2007	-26.29%	+119.88%
2006	N/A	+49.14%
2005	N/A	+72.20%
2004	N/A	-19.22%
2003	N/A	+10.38%
2002	N/A	-46.75%
2001	N/A	+41.47%
2000	N/A	-24.02%
1999	N/A	-23.60%

MDGL vs BMRN Drawdown Comparison

The maximum drawdown for MDGL was -98.40%, occurring on Feb 11, 2016. Recovery took 3162 trading sessions.

The maximum drawdown for BMRN was -90.58%, occurring on Aug 27, 2002. Recovery took 1974 trading sessions.

The current MDGL drawdown is -21.32%. The current BMRN drawdown is -62.76%.

Rank	MDGL	BMRN
#1	-98.40% Jan 28, 2013 - Aug 22, 2025	-90.58% Mar 1, 2000 - Jan 8, 2008
#2	-87.64% Oct 5, 2007 - Jan 22, 2013	-74.89% Feb 14, 2008 - Jul 2, 2012
#3	-51.43% Jun 4, 2007 - Oct 4, 2007	-66.69% Jul 20, 2015 - May 18, 2026
#4	-29.36% Dec 22, 2025 - Mar 3, 2026	-33.02% Feb 27, 2014 - Nov 3, 2014
#5	-18.88% Feb 9, 2007 - Jun 4, 2007	-24.97% Nov 2, 1999 - Jan 14, 2000
#6	-10.10% Sep 30, 2025 - Nov 5, 2025	-24.35% Sep 19, 2013 - Feb 20, 2014
#7	-9.42% Nov 26, 2025 - Dec 22, 2025	-22.16% May 14, 2013 - Sep 5, 2013
#8	-8.01% Sep 8, 2025 - Sep 30, 2025	-15.06% Jul 13, 2012 - Nov 5, 2012
#9	-4.91% Nov 11, 2025 - Nov 17, 2025	-14.15% Jan 14, 2000 - Feb 8, 2000
#10	-4.32% Jan 23, 2013 - Jan 25, 2013	-13.23% Mar 30, 2015 - May 27, 2015
#11	-3.02% Nov 18, 2025 - Nov 24, 2025	-12.73% Jan 9, 2008 - Feb 14, 2008
#12	-1.52% Aug 29, 2025 - Sep 8, 2025	-9.37% Mar 19, 2015 - Mar 27, 2015
#13	-0.59% Aug 22, 2025 - Aug 26, 2025	-8.63% Dec 9, 2014 - Jan 12, 2015
#14	N/A	-7.01% May 27, 2015 - Jun 18, 2015
#15	N/A	-6.98% Sep 9, 2013 - Sep 18, 2013

Correlation

Correlation between MDGL and BMRN is -0.32 which considered as a weak negative correlation - the stocks show a slight tendency to move in opposite directions.

-0.32

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