MCRB vs SCLX

Comparison between Seres Therapeutics Inc (MCRB, Company) and Scilex Holding Company (SCLX, Company).

Both MCRB and SCLX are from the Healthcare sector.

5-Year PerformanceSCLX has outperformed MCRB, delivering a return of -49.0% compared to -56.8%

MCRB vs SCLX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	MCRB(COMPANY)	SCLX(COMPANY)
Market Cap	$63M	$63M
Max Drawdown	99.45%	99.23%
Sharpe Ratio	0.40	1.33
5Y Beta	0.96	0.98
Industry	Biotechnology	Drug Manufacturers - General
P/E Ratio	-1.32	-0.17
Forward P/E	10.26	2.66
PEG Ratio	N/A	-0.00
5Y EPS CAGR	-26.82%	N/A
Debt to Equity	0.00%	-32.41%
Free Cash Flow Yield	-66.83%	-5.41%

Market Cap

MCRB

$63M

Winner

SCLX

$63M

Max Drawdown

MCRB

99.45%

Winner

SCLX

99.23%

Sharpe Ratio

MCRB

0.40

Winner

SCLX

1.33

5Y Beta

Winner

MCRB

0.96

SCLX

0.98

Industry

MCRB

Biotechnology

SCLX

Drug Manufacturers - General

P/E Ratio

Winner

MCRB

-1.32

SCLX

-0.17

Forward P/E

MCRB

10.26

Winner

SCLX

2.66

PEG Ratio

MCRB

N/A

SCLX

-0.00

5Y EPS CAGR

MCRB

-26.82%

SCLX

N/A

Debt to Equity

MCRB

0.00%

Winner

SCLX

-32.41%

Free Cash Flow Yield

MCRB

-66.83%

Winner

SCLX

-5.41%

MCRB vs SCLX - Historical Returns

Returns include dividend reinvestment.

Period	MCRB	SCLX
1 month	-12.91%	+100.62%
3 months	-26.80%	+55.40%
6 months	-56.74%	-17.89%
1 year	-14.49%	+150.45%
5 years(CAGR)	-56.75%	-48.99%
10 years(CAGR)	-36.16%	N/A
Max(CAGR)	-36.85%	-47.02%

MCRB

-12.91%

Winner

SCLX

+100.62%

MCRB

-26.80%

Winner

SCLX

+55.40%

MCRB

-56.74%

Winner

SCLX

-17.89%

MCRB

-14.49%

Winner

SCLX

+150.45%

5Y(CAGR)

MCRB

-56.75%

Winner

SCLX

-48.99%

10Y(CAGR)

MCRB

-36.16%

SCLX

N/A

Max(CAGR)

Winner

MCRB

-36.85%

SCLX

-47.02%

MCRB vs SCLX - Annual Returns (2015 - 2026)

Returns include dividend reinvestment.

Year	MCRB	SCLX
2026	-56.37%	-8.35%
2025	-11.78%	-20.13%
2024	-40.64%	-79.10%
2023	-74.07%	-61.61%
2022	-36.65%	-60.30%
2021	-66.76%	+1.93%
2020	+631.34%	N/A
2019	-28.57%	N/A
2018	-57.16%	N/A
2017	+1.30%	N/A
2016	-70.97%	N/A
2015	-31.73%	N/A

MCRB vs SCLX Drawdown Comparison

The maximum drawdown for MCRB was -99.45%, occurring on Jun 15, 2026. This drawdown has not yet recovered.

The maximum drawdown for SCLX was -99.23%, occurring on Apr 22, 2025. This drawdown has not yet recovered.

The current MCRB drawdown is -99.36%. The current SCLX drawdown is -97.68%.

Rank	MCRB	SCLX
#1	-99.45% Jun 26, 2015 - Jun 15, 2026	-99.23% Apr 12, 2023 - Apr 22, 2025
#2	N/A	-72.67% Nov 8, 2022 - Jan 19, 2023
#3	N/A	-42.23% Jan 20, 2023 - Apr 5, 2023
#4	N/A	-16.08% Oct 26, 2022 - Nov 8, 2022
#5	N/A	-8.13% Apr 10, 2023 - Apr 12, 2023
#6	N/A	-1.26% Jun 27, 2022 - Oct 13, 2022
#7	N/A	-1.21% Mar 11, 2021 - Apr 19, 2021
#8	N/A	-0.80% Apr 19, 2021 - Aug 30, 2021
#9	N/A	-0.59% Nov 2, 2021 - Jan 24, 2022
#10	N/A	-0.50% Oct 18, 2021 - Nov 2, 2021
#11	N/A	-0.40% Jan 24, 2022 - Feb 2, 2022
#12	N/A	-0.39% Mar 17, 2022 - May 4, 2022
#13	N/A	-0.29% May 5, 2022 - May 25, 2022
#14	N/A	-0.29% May 27, 2022 - Jun 21, 2022
#15	N/A	-0.28% Sep 14, 2021 - Oct 14, 2021