LFSC vs SPY

Comparison between F/M EMERALD LIFE SCIENCES INNOVATION ETF (LFSC, ETF) and SPDR S&P 500 ETF Trust (SPY, ETF).

LFSC vs SPY - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	LFSC(ETF)	SPY(ETF)
Net Assets	$101M	$735B
Expense Ratio	0.54%	0.09%
Max Drawdown	29.74%	56.47%
Sharpe Ratio	1.74	1.62
5Y Beta	1.05	1.00
P/E Ratio	-34.20	28.99
Forward P/E	N/A	22.37
5Y Dividends CAGR	N/A	5.43%
5Y EPS CAGR	-9.48%	26.05%
Debt to Equity	-38.12%	32.40%
P/S Ratio	9.00	3.74
P/B Ratio	7.08	5.61

Net Assets

LFSC

$101M

Winner

SPY

$735B

Expense Ratio

LFSC

0.54%

Winner

SPY

0.09%

Max Drawdown

Winner

LFSC

29.74%

SPY

56.47%

Sharpe Ratio

Winner

LFSC

1.74

SPY

1.62

5Y Beta

LFSC

1.05

Winner

SPY

1.00

P/E Ratio

Winner

LFSC

-34.20

SPY

28.99

Forward P/E

LFSC

N/A

SPY

22.37

5Y Dividends CAGR

LFSC

N/A

SPY

5.43%

5Y EPS CAGR

LFSC

-9.48%

Winner

SPY

26.05%

Debt to Equity

Winner

LFSC

-38.12%

SPY

32.40%

P/S Ratio

LFSC

9.00

Winner

SPY

3.74

P/B Ratio

LFSC

7.08

Winner

SPY

5.61

LFSC vs SPY - Holdings Comparison

LFSC and SPY have 0 common holdings. Overlap is 0.00%

LFSC's top 25 holdings weight is 81.26%. SPY's top 25 holdings weight is 52.37%.

Rank	LFSC	SPY
#1	COGENT BIOSCIENCES INC (COGT) - 7.45%	NVIDIA CORP (NVDA) - 8.10%
#2	LIVANOVA PLC (LIVN) - 7.41%	APPLE INC (AAPL) - 7.02%
#3	TRAVERE THERAPEUTICS INC ORDINARY SHARES (TVTX) - 7.34%	MICROSOFT CORP (MSFT) - 4.79%
#4	SPYRE THERAPEUTICS INC (SYRE) - 6.55%	AMAZON.COM INC (AMZN) - 4.02%
#5	GUARDANT HEALTH INC (GH) - 5.20%	ALPHABET INC CLASS A (GOOGL) - 3.51%
#6	MIRUM PHARMACEUTICALS INC (MIRM) - 4.89%	BROADCOM INC (AVGO) - 3.10%
#7	UNITED THERAPEUTICS CORP (UTHR) - 4.41%	ALPHABET INC CLASS C (GOOG) - 2.79%
#8	CORCEPT THERAPEUTICS INC (CORT) - 4.07%	META PLATFORMS INC CLASS A (META) - 2.08%
#9	VERADERMICS INC (MANE) - 3.54%	TESLA INC (TSLA) - 1.89%
#10	SAVARA INC (SVRA) - 3.25%	MICRON TECHNOLOGY INC (MU) - 1.56%
#11	NEKTAR THERAPEUTICS (NKTR) - 3.24%	BERKSHIRE HATHAWAY INC CLASS B (BRK-B) - 1.37%
#12	TREVI THERAPEUTICS INC (TRVI) - 3.23%	ELI LILLY AND CO (LLY) - 1.31%
#13	CYTOKINETICS INC (CYTK) - 3.21%	JPMORGAN CHASE & CO (JPM) - 1.28%
#14	DIANTHUS THERAPEUTICS INC (DNTH) - 2.94%	ADVANCED MICRO DEVICES INC (AMD) - 1.27%
#15	AXSOME THERAPEUTICS INC (AXSM) - 2.89%	EXXON MOBIL CORP (XOM) - 0.97%
#16	TRANSMEDICS GROUP INC (TMDX) - 2.87%	INTEL CORP (INTC) - 0.90%
#17	BILLIONTOONE INC ORDINARY SHARES CLASS A (BLLN) - 2.38%	JOHNSON & JOHNSON (JNJ) - 0.86%
#18	VIRIDIAN THERAPEUTICS INC (VRDN) - 2.20%	VISA INC CLASS A (V) - 0.85%
#19	ICU MEDICAL INC (ICUI) - 2.13%	WALMART INC (WMT) - 0.81%
#20	CORVUS PHARMACEUTICALS INC (CRVS) - 2.06%	CISCO SYSTEMS INC (CSCO) - 0.72%
#21	N/A	COSTCO WHOLESALE CORP (COST) - 0.69%
#22	N/A	CATERPILLAR INC (CAT) - 0.66%
#23	N/A	MASTERCARD INC CLASS A (MA) - 0.62%
#24	N/A	LAM RESEARCH CORP (LRCX) - 0.62%
#25	N/A	ABBVIE INC (ABBV) - 0.58%
Total Holdings	20	505

LFSC vs SPY - Historical Returns

Returns include dividend reinvestment.

Period	LFSC	SPY
1 month	-2.72%	+1.90%
3 months	+8.08%	+8.55%
6 months	+0.54%	+8.18%
1 year	+57.69%	+25.79%
5 years(CAGR)	N/A	+13.32%
10 years(CAGR)	N/A	+15.19%
Max(CAGR)	+30.18%	+8.47%

LFSC

-2.72%

Winner

SPY

+1.90%

LFSC

+8.08%

Winner

SPY

+8.55%

LFSC

+0.54%

Winner

SPY

+8.18%

Winner

LFSC

+57.69%

SPY

+25.79%

5Y(CAGR)

LFSC

N/A

SPY

+13.32%

10Y(CAGR)

LFSC

N/A

SPY

+15.19%

Max(CAGR)

Winner

LFSC

+30.18%

SPY

+8.47%

LFSC vs SPY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	LFSC	SPY
2026	+4.62%	+8.26%
2025	+53.95%	+18.00%
2024	-6.02%	+25.59%
2023	N/A	+26.72%
2022	N/A	-18.64%
2021	N/A	+30.52%
2020	N/A	+17.28%
2019	N/A	+31.09%
2018	N/A	-5.24%
2017	N/A	+20.78%
2016	N/A	+13.59%
2015	N/A	+1.31%
2014	N/A	+14.56%
2013	N/A	+29.00%
2012	N/A	+14.17%
2011	N/A	+0.85%
2010	N/A	+13.14%
2009	N/A	+22.67%
2008	N/A	-36.25%
2007	N/A	+5.32%
2006	N/A	+13.85%
2005	N/A	+5.32%
2004	N/A	+10.75%
2003	N/A	+24.18%
2002	N/A	-22.42%
2001	N/A	-10.13%
2000	N/A	-8.84%
1999	N/A	+8.61%

LFSC vs SPY Drawdown Comparison

The maximum drawdown for LFSC was -29.74%, occurring on Apr 8, 2025. Recovery took 194 trading sessions.

The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.

The current LFSC drawdown is -3.90%. The current SPY drawdown is -2.90%.

Rank	LFSC	SPY
#1	-29.74% Nov 11, 2024 - Aug 22, 2025	-55.20% Oct 9, 2007 - Aug 16, 2012
#2	-16.25% Dec 10, 2025 - May 28, 2026	-47.50% Mar 24, 2000 - Oct 26, 2006
#3	-4.92% Sep 9, 2025 - Sep 18, 2025	-33.70% Feb 19, 2020 - Aug 10, 2020
#4	-4.73% Oct 31, 2025 - Nov 10, 2025	-24.50% Jan 3, 2022 - Dec 13, 2023
#5	-4.60% May 28, 2026 - Jun 2, 2026	-19.34% Sep 20, 2018 - Apr 12, 2019
#6	-4.35% Nov 12, 2025 - Nov 21, 2025	-18.76% Feb 19, 2025 - Jun 26, 2025
#7	-3.55% Nov 28, 2025 - Dec 8, 2025	-13.02% Jul 20, 2015 - Apr 18, 2016
#8	-3.22% Oct 9, 2025 - Oct 15, 2025	-10.10% Jan 26, 2018 - Aug 6, 2018
#9	-3.03% Nov 4, 2024 - Nov 7, 2024	-9.44% Sep 2, 2020 - Nov 11, 2020
#10	-2.42% Sep 22, 2025 - Sep 30, 2025	-9.30% Jan 19, 2000 - Mar 17, 2000
#11	-2.33% Oct 20, 2025 - Oct 27, 2025	-9.05% Jul 19, 2007 - Oct 5, 2007
#12	-1.84% Aug 22, 2025 - Aug 27, 2025	-8.88% Jan 27, 2026 - Apr 14, 2026
#13	-1.00% Sep 18, 2025 - Sep 22, 2025	-8.41% Jul 16, 2024 - Sep 19, 2024
#14	-0.78% Sep 30, 2025 - Oct 3, 2025	-7.35% Sep 14, 2012 - Jan 2, 2013
#15	-0.60% Oct 27, 2025 - Oct 30, 2025	-7.27% Sep 18, 2014 - Oct 31, 2014

Correlation

Correlation between LFSC and SPY is 0.93 which considered as a very strong positive correlation - the stocks move almost identically together.

0.93

-101

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LFSC vs SPY

LFSC vs SPY - Performance Comparison

Key Characteristics

LFSC vs SPY - Holdings Comparison

LFSC vs SPY - Historical Returns

LFSC vs SPY - Annual Returns (1999 - 2026)

LFSC vs SPY Drawdown Comparison

Correlation

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