KYMR vs SPY

Comparison between Kymera Therapeutics Inc (KYMR, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).

5-Year PerformanceSPY has outperformed KYMR, delivering a return of +13.7% compared to +12.5%

KYMR vs SPY - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	KYMR(COMPANY)	SPY(ETF)
Market Cap / Net Assets	$7.03B	$735B
Expense Ratio	N/A	0.09%
Max Drawdown	87.51%	56.47%
Sharpe Ratio	1.63	1.76
5Y Beta	1.55	1.00
Industry	Biotechnology	N/A
P/E Ratio	-20.66	28.46
Forward P/E	N/A	21.99
PEG Ratio	-1.95	N/A
5Y Dividends CAGR	N/A	5.43%
5Y EPS CAGR	N/A	25.20%
Debt to Equity	0.00%	33.33%
Free Cash Flow Yield	-3.47%	N/A
P/S Ratio	136.77	3.65
P/B Ratio	4.60	5.50

Market Cap / Net Assets

KYMR

$7.03B

Winner

SPY

$735B

Expense Ratio

KYMR

N/A

SPY

0.09%

Max Drawdown

KYMR

87.51%

Winner

SPY

56.47%

Sharpe Ratio

KYMR

1.63

Winner

SPY

1.76

5Y Beta

KYMR

1.55

Winner

SPY

1.00

Industry

KYMR

Biotechnology

SPY

N/A

P/E Ratio

Winner

KYMR

-20.66

SPY

28.46

Forward P/E

KYMR

N/A

SPY

21.99

PEG Ratio

KYMR

-1.95

SPY

N/A

5Y Dividends CAGR

KYMR

N/A

SPY

5.43%

5Y EPS CAGR

KYMR

N/A

SPY

25.20%

Debt to Equity

Winner

KYMR

0.00%

SPY

33.33%

Free Cash Flow Yield

KYMR

-3.47%

SPY

N/A

P/S Ratio

KYMR

136.77

Winner

SPY

3.65

P/B Ratio

Winner

KYMR

4.60

SPY

5.50

KYMR vs SPY - Historical Returns

Returns include dividend reinvestment.

Period	KYMR	SPY
1 month	-7.63%	+5.60%
3 months	-0.16%	+8.72%
6 months	+26.59%	+10.63%
1 year	+173.85%	+26.62%
5 years(CAGR)	+12.54%	+13.70%
10 years(CAGR)	N/A	+15.47%
Max(CAGR)	+17.11%	+8.50%

KYMR

-7.63%

Winner

SPY

+5.60%

KYMR

-0.16%

Winner

SPY

+8.72%

Winner

KYMR

+26.59%

SPY

+10.63%

Winner

KYMR

+173.85%

SPY

+26.62%

5Y(CAGR)

KYMR

+12.54%

Winner

SPY

+13.70%

10Y(CAGR)

KYMR

N/A

SPY

+15.47%

Max(CAGR)

Winner

KYMR

+17.11%

SPY

+8.50%

KYMR vs SPY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	KYMR	SPY
2026	+12.99%	+8.50%
2025	+90.29%	+18.00%
2024	+58.70%	+25.59%
2023	+2.50%	+26.72%
2022	-61.41%	-18.64%
2021	+3.02%	+30.52%
2020	+86.41%	+17.28%
2019	N/A	+31.09%
2018	N/A	-5.24%
2017	N/A	+20.78%
2016	N/A	+13.59%
2015	N/A	+1.31%
2014	N/A	+14.56%
2013	N/A	+29.00%
2012	N/A	+14.17%
2011	N/A	+0.85%
2010	N/A	+13.14%
2009	N/A	+22.67%
2008	N/A	-36.25%
2007	N/A	+5.32%
2006	N/A	+13.85%
2005	N/A	+5.32%
2004	N/A	+10.75%
2003	N/A	+24.18%
2002	N/A	-22.42%
2001	N/A	-10.13%
2000	N/A	-8.84%
1999	N/A	+8.61%

KYMR vs SPY Drawdown Comparison

The maximum drawdown for KYMR was -87.51%, occurring on Oct 27, 2023. Recovery took 1242 trading sessions.

The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.

The current KYMR drawdown is -13.49%. The current SPY drawdown is -1.20%.

Rank	KYMR	SPY
#1	-87.51% Dec 28, 2020 - Dec 8, 2025	-55.20% Oct 9, 2007 - Aug 16, 2012
#2	-27.74% Dec 8, 2025 - Feb 26, 2026	-47.50% Mar 24, 2000 - Oct 26, 2006
#3	-21.69% Feb 26, 2026 - Mar 24, 2026	-33.70% Feb 19, 2020 - Aug 10, 2020
#4	-21.57% Aug 28, 2020 - Oct 8, 2020	-24.50% Jan 3, 2022 - Dec 13, 2023
#5	-14.49% Aug 21, 2020 - Aug 27, 2020	-19.34% Sep 20, 2018 - Apr 12, 2019
#6	-11.90% Oct 19, 2020 - Nov 4, 2020	-18.76% Feb 19, 2025 - Jun 26, 2025
#7	-10.81% Nov 17, 2020 - Dec 2, 2020	-13.02% Jul 20, 2015 - Apr 18, 2016
#8	-7.05% Dec 4, 2020 - Dec 8, 2020	-10.10% Jan 26, 2018 - Aug 6, 2018
#9	-6.20% Dec 14, 2020 - Dec 18, 2020	-9.44% Sep 2, 2020 - Nov 11, 2020
#10	-4.52% Oct 13, 2020 - Oct 15, 2020	-9.30% Jan 19, 2000 - Mar 17, 2000
#11	-4.05% Nov 11, 2020 - Nov 17, 2020	-9.05% Jul 19, 2007 - Oct 5, 2007
#12	-2.58% Dec 2, 2020 - Dec 4, 2020	-8.88% Jan 27, 2026 - Apr 14, 2026
#13	-1.08% Oct 15, 2020 - Oct 19, 2020	-8.41% Jul 16, 2024 - Sep 19, 2024
#14	-0.39% Dec 8, 2020 - Dec 10, 2020	-7.35% Sep 14, 2012 - Jan 2, 2013
#15	N/A	-7.27% Sep 18, 2014 - Oct 31, 2014