KRYS vs SAIA

Comparison between Krystal Biotech Inc (KRYS, Company) and Saia Inc (SAIA, Company).

KRYS is from the Healthcare sector, while SAIA is from the Industrials sector.

5-Year PerformanceKRYS has outperformed SAIA, delivering a return of +39.6% compared to +15.3%

KRYS vs SAIA - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	KRYS(COMPANY)	SAIA(COMPANY)
Market Cap	$11B	$11B
Max Drawdown	53.42%	80.35%
Sharpe Ratio	2.55	0.91
5Y Beta	0.93	1.44
Industry	Biotechnology	Trucking
P/E Ratio	48.60	43.31
Forward P/E	49.51	34.97
PEG Ratio	0.61	2.10
5Y EPS CAGR	N/A	11.22%
Debt to Equity	0.00%	4.26%
Free Cash Flow Yield	2.15%	1.76%
P/S Ratio	26.65	3.39
P/B Ratio	8.67	4.23

Market Cap

KRYS

$11B

Winner

SAIA

$11B

Max Drawdown

Winner

KRYS

53.42%

SAIA

80.35%

Sharpe Ratio

Winner

KRYS

2.55

SAIA

0.91

5Y Beta

Winner

KRYS

0.93

SAIA

1.44

Industry

KRYS

Biotechnology

SAIA

Trucking

P/E Ratio

KRYS

48.60

Winner

SAIA

43.31

Forward P/E

KRYS

49.51

Winner

SAIA

34.97

PEG Ratio

Winner

KRYS

0.61

SAIA

2.10

5Y EPS CAGR

KRYS

N/A

SAIA

11.22%

Debt to Equity

Winner

KRYS

0.00%

SAIA

4.26%

Free Cash Flow Yield

Winner

KRYS

2.15%

SAIA

1.76%

P/S Ratio

KRYS

26.65

Winner

SAIA

3.39

P/B Ratio

KRYS

8.67

Winner

SAIA

4.23

KRYS vs SAIA - Historical Returns

Returns include dividend reinvestment.

Period	KRYS	SAIA
1 month	+17.09%	-9.25%
3 months	+41.24%	+4.72%
6 months	+39.94%	+14.68%
1 year	+144.30%	+37.17%
5 years(CAGR)	+39.63%	+15.30%
10 years(CAGR)	+49.46%	+32.00%
Max(CAGR)	+49.46%	+17.56%

Winner

KRYS

+17.09%

SAIA

-9.25%

Winner

KRYS

+41.24%

SAIA

+4.72%

Winner

KRYS

+39.94%

SAIA

+14.68%

Winner

KRYS

+144.30%

SAIA

+37.17%

5Y(CAGR)

Winner

KRYS

+39.63%

SAIA

+15.30%

10Y(CAGR)

Winner

KRYS

+49.46%

SAIA

+32.00%

Max(CAGR)

Winner

KRYS

+49.46%

SAIA

+17.56%

KRYS vs SAIA - Annual Returns (2002 - 2026)

Returns include dividend reinvestment.

Year	KRYS	SAIA
2026	+48.16%	+24.81%
2025	+57.53%	-26.68%
2024	+25.37%	+6.60%
2023	+56.58%	+110.07%
2022	+9.86%	-33.39%
2021	+17.72%	+87.31%
2020	+5.28%	+92.77%
2019	+142.47%	+70.74%
2018	+126.36%	-21.93%
2017	-1.13%	+57.57%
2016	N/A	+102.62%
2015	N/A	-60.06%
2014	N/A	+81.39%
2013	N/A	+104.14%
2012	N/A	+76.09%
2011	N/A	-25.36%
2010	N/A	+15.45%
2009	N/A	+31.73%
2008	N/A	-14.82%
2007	N/A	-43.95%
2006	N/A	+4.08%
2005	N/A	-7.29%
2004	N/A	+34.62%
2003	N/A	+73.03%
2002	N/A	-25.93%

KRYS vs SAIA Drawdown Comparison

The maximum drawdown for KRYS was -53.42%, occurring on Nov 26, 2021. Recovery took 190 trading sessions.

The maximum drawdown for SAIA was -80.35%, occurring on Nov 20, 2008. Recovery took 1612 trading sessions.

The current KRYS drawdown is -3.26%. The current SAIA drawdown is -30.55%.

Rank	KRYS	SAIA
#1	-53.42% Mar 1, 2021 - Nov 29, 2021	-80.35% Oct 16, 2006 - Mar 14, 2013
#2	-46.65% Feb 12, 2020 - Jan 8, 2021	-65.82% Dec 4, 2014 - Aug 31, 2017
#3	-44.55% Nov 29, 2021 - Apr 13, 2023	-60.94% Mar 6, 2024 - Apr 29, 2025
#4	-42.26% Jul 26, 2024 - Nov 24, 2025	-53.15% Nov 17, 2021 - Jul 17, 2023
#5	-35.34% Jul 22, 2019 - Nov 13, 2019	-49.18% Sep 12, 2002 - Jul 2, 2003
#6	-28.43% Sep 11, 2018 - Oct 16, 2018	-44.51% Jun 23, 2004 - Jan 25, 2006
#7	-27.86% Dec 13, 2019 - Feb 12, 2020	-39.57% Jun 12, 2018 - Sep 4, 2019
#8	-26.81% Oct 18, 2017 - Mar 16, 2018	-39.00% Oct 28, 2019 - May 26, 2020
#9	-26.58% Jan 8, 2019 - Mar 25, 2019	-24.09% Mar 15, 2006 - Aug 16, 2006
#10	-26.34% Jun 13, 2023 - Jan 22, 2024	-21.51% Sep 1, 2023 - Dec 21, 2023
#11	-24.99% May 14, 2019 - Jun 24, 2019	-21.10% May 7, 2021 - Aug 11, 2021
#12	-24.14% Oct 16, 2018 - Nov 30, 2018	-19.00% Sep 22, 2003 - Dec 2, 2003
#13	-23.42% Mar 16, 2018 - Jun 6, 2018	-18.30% Jul 11, 2013 - Oct 22, 2013
#14	-19.86% Nov 30, 2018 - Jan 7, 2019	-17.02% Jan 25, 2018 - May 21, 2018
#15	-17.56% Jan 22, 2024 - Feb 26, 2024	-14.17% Oct 22, 2013 - Mar 4, 2014