IREN vs NBIX

Comparison between Iris Energy Ltd (IREN, Company) and Neurocrine Biosciences Inc (NBIX, Company).

IREN is from the Financial Services sector, while NBIX is from the Healthcare sector.

5-Year PerformanceIREN has outperformed NBIX, delivering a return of +15.6% compared to +10.4%

IREN vs NBIX - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	IREN(COMPANY)	NBIX(COMPANY)
Market Cap	$17B	$17B
Max Drawdown	95.73%	97.21%
Sharpe Ratio	1.86	0.83
5Y Beta	2.73	0.80
Industry	Capital Markets	Drug Manufacturers - Specialty & Generic
P/E Ratio	606.41	24.82
Forward P/E	136.99	23.42
PEG Ratio	4.05	0.21
5Y EPS CAGR	N/A	9.25%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-8.70%	4.95%
P/S Ratio	22.99	5.38
P/B Ratio	6.75	4.90

Market Cap

Winner

IREN

$17B

NBIX

$17B

Max Drawdown

Winner

IREN

95.73%

NBIX

97.21%

Sharpe Ratio

Winner

IREN

1.86

NBIX

0.83

5Y Beta

IREN

2.73

Winner

NBIX

0.80

Industry

IREN

Capital Markets

NBIX

Drug Manufacturers - Specialty & Generic

P/E Ratio

IREN

606.41

Winner

NBIX

24.82

Forward P/E

IREN

136.99

Winner

NBIX

23.42

PEG Ratio

IREN

4.05

Winner

NBIX

0.21

5Y EPS CAGR

IREN

N/A

NBIX

9.25%

Debt to Equity

IREN

0.00%

NBIX

0.00%

Free Cash Flow Yield

IREN

-8.70%

Winner

NBIX

4.95%

P/S Ratio

IREN

22.99

Winner

NBIX

5.38

P/B Ratio

IREN

6.75

Winner

NBIX

4.90

IREN vs NBIX - Historical Returns

Returns include dividend reinvestment.

Period	IREN	NBIX
1 month	-20.14%	+5.43%
3 months	+15.23%	+25.20%
6 months	+13.72%	+11.74%
1 year	+302.19%	+28.49%
5 years(CAGR)	+15.65%	+10.36%
10 years(CAGR)	N/A	+14.26%
Max(CAGR)	+15.65%	+12.57%

IREN

-20.14%

Winner

NBIX

+5.43%

IREN

+15.23%

Winner

NBIX

+25.20%

Winner

IREN

+13.72%

NBIX

+11.74%

Winner

IREN

+302.19%

NBIX

+28.49%

5Y(CAGR)

Winner

IREN

+15.65%

NBIX

+10.36%

10Y(CAGR)

IREN

N/A

NBIX

+14.26%

Max(CAGR)

Winner

IREN

+15.65%

NBIX

+12.57%

IREN vs NBIX - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	IREN	NBIX
2026	+11.80%	+16.77%
2025	+261.09%	+2.88%
2024	+44.41%	+3.62%
2023	+500.84%	+9.73%
2022	-91.79%	+35.01%
2021	-33.87%	-11.16%
2020	N/A	-11.50%
2019	N/A	+53.36%
2018	N/A	-9.95%
2017	N/A	+100.70%
2016	N/A	-26.07%
2015	N/A	+147.68%
2014	N/A	+133.93%
2013	N/A	+14.74%
2012	N/A	-12.51%
2011	N/A	+10.82%
2010	N/A	+184.01%
2009	N/A	-16.82%
2008	N/A	-29.20%
2007	N/A	-55.79%
2006	N/A	-83.61%
2005	N/A	+27.97%
2004	N/A	-11.17%
2003	N/A	+20.11%
2002	N/A	-9.71%
2001	N/A	+59.40%
2000	N/A	+31.89%
1999	N/A	+253.57%

IREN vs NBIX Drawdown Comparison

The maximum drawdown for IREN was -95.73%, occurring on Dec 28, 2022. Recovery took 946 trading sessions.

The maximum drawdown for NBIX was -97.21%, occurring on Nov 12, 2009. Recovery took 2931 trading sessions.

The current IREN drawdown is -37.52%. The current NBIX drawdown is -1.89%.

Rank	IREN	NBIX
#1	-95.73% Nov 19, 2021 - Aug 29, 2025	-97.21% Mar 15, 2006 - Nov 2, 2017
#2	-58.62% Nov 5, 2025 - Mar 30, 2026	-66.15% Mar 3, 2000 - Nov 20, 2001
#3	-25.49% Oct 14, 2025 - Nov 5, 2025	-54.12% Dec 24, 2001 - Jun 5, 2003
#4	-11.20% Sep 24, 2025 - Oct 3, 2025	-50.71% Apr 27, 2004 - Feb 27, 2006
#5	-10.24% Sep 2, 2025 - Sep 9, 2025	-46.39% Jul 15, 2020 - Jan 17, 2024
#6	-6.39% Oct 9, 2025 - Oct 13, 2025	-45.71% Sep 4, 2018 - Jun 19, 2020
#7	-4.29% Nov 17, 2021 - Nov 19, 2021	-42.89% Jan 30, 2025 - Nov 5, 2025
#8	-4.17% Sep 17, 2025 - Sep 19, 2025	-28.57% Jan 21, 2000 - Feb 16, 2000
#9	-2.58% Oct 7, 2025 - Oct 9, 2025	-27.12% Aug 1, 2024 - Jan 30, 2025
#10	-2.32% Sep 10, 2025 - Sep 12, 2025	-22.86% Dec 2, 1999 - Dec 13, 1999
#11	-1.86% Sep 15, 2025 - Sep 17, 2025	-21.32% Jun 16, 2003 - Jan 23, 2004
#12	-0.31% Sep 22, 2025 - Sep 24, 2025	-20.90% Dec 10, 2025 - May 12, 2026
#13	N/A	-19.01% Dec 29, 1999 - Jan 10, 2000
#14	N/A	-18.53% Mar 9, 2018 - May 15, 2018
#15	N/A	-13.74% Jan 26, 2004 - Mar 4, 2004