IPHA vs KPTI

Comparison between Innate Pharma (IPHA, Company) and Karyopharm Therapeutics Inc (KPTI, Company).

Both IPHA and KPTI are from the Healthcare sector.

5-Year PerformanceIPHA has outperformed KPTI, delivering a return of -11.8% compared to -44.3%

IPHA vs KPTI - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	IPHA(COMPANY)	KPTI(COMPANY)
Market Cap	$162M	$162M
Max Drawdown	85.73%	99.50%
Sharpe Ratio	0.27	1.05
5Y Beta	0.62	0.83
Industry	Biotechnology	Biotechnology
P/E Ratio	-1.34	-0.49
PEG Ratio	-0.01	-0.00
5Y EPS CAGR	1.02%	-18.43%
Debt to Equity	-104.00%	0.00%
Free Cash Flow Yield	-65.18%	-36.52%
P/S Ratio	18.51	1.08
P/B Ratio	20.10	12.05

Market Cap

Winner

IPHA

$162M

KPTI

$162M

Max Drawdown

Winner

IPHA

85.73%

KPTI

99.50%

Sharpe Ratio

IPHA

0.27

Winner

KPTI

1.05

5Y Beta

Winner

IPHA

0.62

KPTI

0.83

Industry

IPHA

Biotechnology

KPTI

Biotechnology

P/E Ratio

Winner

IPHA

-1.34

KPTI

-0.49

PEG Ratio

Winner

IPHA

-0.01

KPTI

-0.00

5Y EPS CAGR

Winner

IPHA

1.02%

KPTI

-18.43%

Debt to Equity

Winner

IPHA

-104.00%

KPTI

0.00%

Free Cash Flow Yield

IPHA

-65.18%

Winner

KPTI

-36.52%

P/S Ratio

IPHA

18.51

Winner

KPTI

1.08

P/B Ratio

IPHA

20.10

Winner

KPTI

12.05

IPHA vs KPTI - Historical Returns

Returns include dividend reinvestment.

Period	IPHA	KPTI
1 month	-6.88%	-26.53%
3 months	+28.47%	-18.97%
6 months	-1.68%	+7.59%
1 year	-11.07%	+45.88%
5 years(CAGR)	-11.81%	-44.33%
10 years(CAGR)	N/A	-23.66%
Max(CAGR)	-16.68%	-24.22%

Winner

IPHA

-6.88%

KPTI

-26.53%

Winner

IPHA

+28.47%

KPTI

-18.97%

IPHA

-1.68%

Winner

KPTI

+7.59%

IPHA

-11.07%

Winner

KPTI

+45.88%

5Y(CAGR)

Winner

IPHA

-11.81%

KPTI

-44.33%

10Y(CAGR)

IPHA

N/A

KPTI

-23.66%

Max(CAGR)

Winner

IPHA

-16.68%

KPTI

-24.22%

IPHA vs KPTI - Annual Returns (2013 - 2026)

Returns include dividend reinvestment.

Year	IPHA	KPTI
2026	-3.30%	-1.39%
2025	-6.42%	-39.54%
2024	-32.35%	-24.96%
2023	-17.65%	-73.47%
2022	-22.29%	-52.11%
2021	+5.80%	-62.00%
2020	-43.97%	-17.31%
2019	+6.45%	+100.52%
2018	N/A	-5.54%
2017	N/A	-0.41%
2016	N/A	-30.16%
2015	N/A	-65.12%
2014	N/A	+62.67%
2013	N/A	+42.80%

IPHA vs KPTI Drawdown Comparison

The maximum drawdown for IPHA was -85.73%, occurring on Mar 20, 2026. This drawdown has not yet recovered.

The maximum drawdown for KPTI was -99.50%, occurring on Apr 1, 2025. This drawdown has not yet recovered.

The current IPHA drawdown is -78.54%. The current KPTI drawdown is -99.00%.

Rank	IPHA	KPTI
#1	-85.73% May 11, 2020 - Mar 20, 2026	-99.50% Jun 13, 2014 - Apr 1, 2025
#2	-52.20% Feb 19, 2020 - May 11, 2020	-43.74% Mar 6, 2014 - Jun 13, 2014
#3	-12.06% Nov 11, 2019 - Jan 2, 2020	-10.42% Dec 20, 2013 - Jan 15, 2014
#4	-10.16% Jan 23, 2020 - Feb 13, 2020	-9.08% Jan 31, 2014 - Feb 12, 2014
#5	-9.99% Jan 8, 2020 - Jan 23, 2020	-8.83% Mar 4, 2014 - Mar 6, 2014
#6	-8.86% Oct 21, 2019 - Nov 5, 2019	-5.88% Jan 22, 2014 - Jan 30, 2014
#7	-4.27% Feb 13, 2020 - Feb 18, 2020	-4.87% Feb 27, 2014 - Mar 4, 2014
#8	-3.22% Nov 7, 2019 - Nov 11, 2019	-4.36% Feb 13, 2014 - Feb 20, 2014
#9	-1.78% Jan 2, 2020 - Jan 6, 2020	-3.39% Dec 9, 2013 - Dec 13, 2013
#10	N/A	-1.60% Nov 29, 2013 - Dec 6, 2013
#11	N/A	-1.48% Nov 8, 2013 - Nov 29, 2013
#12	N/A	-0.44% Nov 6, 2013 - Nov 8, 2013