IONS vs CR
Comparison between Ionis Pharmaceuticals Inc (IONS, Company) and Crane Company (CR, Company).
IONS is from the Healthcare sector, while CR is from the Industrials sector.
IONS vs CR - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap
IONS
$12B
Winner
CR
$12B
Max Drawdown
IONS
91.72%
Winner
CR
28.21%
Sharpe Ratio
Winner
IONS
1.67
CR
0.65
5Y Beta
Winner
IONS
0.72
CR
1.29
Industry
IONS
Biotechnology
CR
Specialty Industrial Machinery
P/E Ratio
Winner
IONS
-70.34
CR
37.91
Forward P/E
IONS
90.91
Winner
CR
30.96
PEG Ratio
IONS
-1.49
CR
N/A
Dividend Yield
IONS
N/A
CR
0.46%
5Y EPS CAGR
IONS
-21.44%
CR
N/A
Debt to Equity
IONS
88.01%
Winner
CR
57.14%
Free Cash Flow Yield
IONS
-7.90%
Winner
CR
-0.24%
IONS vs CR - Historical Returns
Returns include dividend reinvestment.
1M
IONS
+2.21%
Winner
CR
+26.02%
3M
IONS
+3.42%
Winner
CR
+22.91%
6M
IONS
-4.52%
Winner
CR
+16.08%
1Y
Winner
IONS
+100.27%
CR
+21.08%
5Y(CAGR)
IONS
+14.42%
CR
N/A
10Y(CAGR)
IONS
+12.68%
CR
N/A
Max(CAGR)
IONS
+7.52%
Winner
CR
+41.25%
IONS vs CR - Annual Returns (1999 - 2026)
Returns include dividend reinvestment.
| Year | IONS | CR |
|---|---|---|
| 2026 | -6.97% | +14.90% |
| 2025 | +128.05% | +22.80% |
| 2024 | -33.88% | +30.50% |
| 2023 | +34.62% | +65.09% |
| 2022 | +15.86% | N/A |
| 2021 | -46.41% | N/A |
| 2020 | -7.14% | N/A |
| 2019 | +12.35% | N/A |
| 2018 | +9.77% | N/A |
| 2017 | +6.25% | N/A |
| 2016 | -22.45% | N/A |
| 2015 | +0.58% | N/A |
| 2014 | +54.85% | N/A |
| 2013 | +268.21% | N/A |
| 2012 | +44.00% | N/A |
| 2011 | -29.93% | N/A |
| 2010 | -10.20% | N/A |
| 2009 | -23.22% | N/A |
| 2008 | -7.80% | N/A |
| 2007 | +44.10% | N/A |
| 2006 | +111.81% | N/A |
| 2005 | -9.66% | N/A |
| 2004 | -13.36% | N/A |
| 2003 | -4.97% | N/A |
| 2002 | -68.69% | N/A |
| 2001 | +130.55% | N/A |
| 2000 | +77.49% | N/A |
| 1999 | -44.34% | N/A |
IONS vs CR Drawdown Comparison
The maximum drawdown for IONS was -91.43%, occurring on Mar 18, 2003. Recovery took 3357 trading sessions.
The maximum drawdown for CR was -28.02%, occurring on Apr 8, 2025. Recovery took 131 trading sessions.
The current IONS drawdown is -14.31%.
| Rank | IONS | CR |
|---|---|---|
| #1 | -91.43% Mar 6, 2000 - Jul 11, 2013 | -28.02% Nov 26, 2024 - Jun 9, 2025 |
| #2 | -73.25% Mar 19, 2015 - Mar 14, 2019 | -23.39% Jan 21, 2026 - Jun 18, 2026 |
| #3 | -70.39% Apr 8, 2019 - Feb 6, 2026 | -15.63% Apr 17, 2023 - Jun 23, 2023 |
| #4 | -68.14% Dec 2, 1999 - Mar 1, 2000 | -12.52% Jul 31, 2024 - Oct 16, 2024 |
| #5 | -61.05% Feb 21, 2014 - Dec 10, 2014 | -12.10% Jul 28, 2023 - Oct 31, 2023 |
| #6 | -28.35% Jul 12, 2013 - Sep 19, 2013 | -11.69% Aug 13, 2025 - Jan 8, 2026 |
| #7 | -20.89% Sep 23, 2013 - Nov 27, 2013 | -8.73% Oct 17, 2024 - Nov 5, 2024 |
| #8 | -19.78% Jan 12, 2015 - Mar 19, 2015 | -6.50% May 15, 2024 - Jul 15, 2024 |
| #9 | -19.45% Feb 6, 2026 - Mar 24, 2026 | -6.25% Apr 3, 2024 - Apr 23, 2024 |
| #10 | -11.84% Dec 12, 2014 - Dec 19, 2014 | -6.14% Jan 22, 2024 - Jan 30, 2024 |
| #11 | -11.49% Dec 19, 2014 - Jan 5, 2015 | -6.10% Feb 8, 2024 - Mar 7, 2024 |
| #12 | -8.95% Jan 31, 2014 - Feb 13, 2014 | -5.28% Nov 27, 2023 - Dec 15, 2023 |
| #13 | -8.58% Nov 11, 1999 - Nov 17, 1999 | -4.84% Jul 29, 2024 - Jul 31, 2024 |
| #14 | -7.67% Jan 22, 2014 - Jan 31, 2014 | -4.77% Dec 28, 2023 - Jan 22, 2024 |
| #15 | -7.49% Dec 23, 2013 - Jan 8, 2014 | -4.51% Jun 12, 2025 - Jun 26, 2025 |
Correlation
Correlation between IONS and CR is 0.48 which considered as a weak positive correlation - the stocks show a slight tendency to move together.
0.48
-101
Dividend Comparison (1999 - 2026)
IONS vs CR dividend yield comparison.
| Year | IONS | CR |
|---|---|---|
| 2026 | 0.00% | 0.24% |
| 2025 | 0.00% | 0.50% |
| 2024 | 0.00% | 0.54% |
| 2023 | 0.00% | 0.46% |
| 2000 | 4.85% | 0.00% |
| 1999 | 3.52% | 0.00% |
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