IONS vs AGI

Comparison between Ionis Pharmaceuticals Inc (IONS, Company) and Alamos Gold Inc - Class A (AGI, Company).

IONS is from the Healthcare sector, while AGI is from the Basic Materials sector.

5-Year PerformanceAGI has outperformed IONS, delivering a return of +33.3% compared to +15.8%

IONS vs AGI - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	IONS(COMPANY)	AGI(COMPANY)
Market Cap	$13B	$13B
Max Drawdown	91.72%	88.85%
Sharpe Ratio	1.60	0.55
5Y Beta	0.72	0.71
Industry	Biotechnology	Gold
P/E Ratio	-72.62	11.96
Forward P/E	90.91	12.48
PEG Ratio	-1.53	0.04
Dividend Yield	N/A	0.37%
5Y Dividends CAGR	N/A	15.63%
5Y EPS CAGR	-21.44%	N/A
Debt to Equity	88.01%	4.77%
Free Cash Flow Yield	-7.65%	2.73%
P/S Ratio	12.07	6.10
P/B Ratio	25.73	2.74

Market Cap

Winner

IONS

$13B

AGI

$13B

Max Drawdown

IONS

91.72%

Winner

AGI

88.85%

Sharpe Ratio

Winner

IONS

1.60

AGI

0.55

5Y Beta

IONS

0.72

Winner

AGI

0.71

Industry

IONS

Biotechnology

AGI

Gold

P/E Ratio

Winner

IONS

-72.62

AGI

11.96

Forward P/E

IONS

90.91

Winner

AGI

12.48

PEG Ratio

Winner

IONS

-1.53

AGI

0.04

Dividend Yield

IONS

N/A

AGI

0.37%

5Y Dividends CAGR

IONS

N/A

AGI

15.63%

5Y EPS CAGR

IONS

-21.44%

AGI

N/A

Debt to Equity

IONS

88.01%

Winner

AGI

4.77%

Free Cash Flow Yield

IONS

-7.65%

Winner

AGI

2.73%

P/S Ratio

IONS

12.07

Winner

AGI

6.10

P/B Ratio

IONS

25.73

Winner

AGI

2.74

IONS vs AGI - Historical Returns

Returns include dividend reinvestment.

Period	IONS	AGI
1 month	+6.72%	-22.15%
3 months	+9.35%	-22.29%
6 months	+1.56%	-23.10%
1 year	+104.07%	+20.11%
5 years(CAGR)	+15.83%	+33.34%
10 years(CAGR)	+14.69%	+15.01%
Max(CAGR)	+7.88%	+16.99%

Winner

IONS

+6.72%

AGI

-22.15%

Winner

IONS

+9.35%

AGI

-22.29%

Winner

IONS

+1.56%

AGI

-23.10%

Winner

IONS

+104.07%

AGI

+20.11%

5Y(CAGR)

IONS

+15.83%

Winner

AGI

+33.34%

10Y(CAGR)

IONS

+14.69%

Winner

AGI

+15.01%

Max(CAGR)

IONS

+7.88%

Winner

AGI

+16.99%

IONS vs AGI - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	IONS	AGI
2026	+1.90%	-18.38%
2025	+128.05%	+100.99%
2024	-33.88%	+41.61%
2023	+34.62%	+31.09%
2022	+15.86%	+36.85%
2021	-46.41%	-19.22%
2020	-7.14%	+48.86%
2019	+12.35%	+60.84%
2018	+9.77%	-45.74%
2017	+6.25%	-10.10%
2016	-22.45%	+99.43%
2015	+0.58%	-55.07%
2014	+54.85%	-41.18%
2013	+268.21%	-31.82%
2012	+44.00%	-1.22%
2011	-29.93%	-9.74%
2010	-10.20%	+55.17%
2009	-23.22%	+71.29%
2008	-7.80%	+14.26%
2007	+44.10%	-33.62%
2006	+111.81%	+37.22%
2005	-9.66%	+89.41%
2004	-13.36%	+48.08%
2003	-4.97%	+122.58%
2002	-68.69%	N/A
2001	+130.55%	N/A
2000	+77.49%	N/A
1999	-44.34%	N/A

IONS vs AGI Drawdown Comparison

The maximum drawdown for IONS was -91.43%, occurring on Mar 18, 2003. Recovery took 3357 trading sessions.

The maximum drawdown for AGI was -88.13%, occurring on Jan 20, 2016. Recovery took 3446 trading sessions.

The current IONS drawdown is -6.15%. The current AGI drawdown is -43.34%.

Rank	IONS	AGI
#1	-91.43% Mar 6, 2000 - Jul 11, 2013	-88.13% Dec 6, 2010 - Aug 16, 2024
#2	-73.25% Mar 19, 2015 - Mar 14, 2019	-70.76% May 11, 2006 - Nov 13, 2009
#3	-70.39% Apr 8, 2019 - Feb 6, 2026	-49.30% Jan 12, 2004 - Sep 30, 2004
#4	-68.14% Dec 2, 1999 - Mar 1, 2000	-45.49% Mar 2, 2026 - Jun 24, 2026
#5	-61.05% Feb 21, 2014 - Dec 10, 2014	-31.01% Dec 29, 2004 - Sep 15, 2005
#6	-28.35% Jul 12, 2013 - Sep 19, 2013	-24.73% Mar 17, 2003 - Jun 20, 2003
#7	-20.89% Sep 23, 2013 - Nov 27, 2013	-21.52% Oct 31, 2003 - Jan 12, 2004
#8	-19.78% Jan 12, 2015 - Mar 19, 2015	-21.50% Apr 16, 2025 - Aug 29, 2025
#9	-19.45% Feb 6, 2026 - Mar 24, 2026	-20.73% Jan 14, 2010 - Mar 5, 2010
#10	-11.84% Dec 12, 2014 - Dec 19, 2014	-19.91% Oct 16, 2025 - Nov 28, 2025
#11	-11.49% Dec 19, 2014 - Jan 5, 2015	-19.82% Jun 18, 2010 - Sep 7, 2010
#12	-8.95% Jan 31, 2014 - Feb 13, 2014	-19.68% Jun 20, 2003 - Jul 29, 2003
#13	-8.58% Nov 11, 1999 - Nov 17, 1999	-18.04% Nov 18, 2004 - Dec 29, 2004
#14	-7.67% Jan 22, 2014 - Jan 31, 2014	-17.96% Oct 22, 2024 - Feb 3, 2025
#15	-7.49% Dec 23, 2013 - Jan 8, 2014	-17.11% Jan 28, 2026 - Feb 10, 2026

Correlation

Correlation between IONS and AGI is 0.30 which considered as a weak positive correlation - the stocks show a slight tendency to move together.

0.30

-101

Dividend Comparison (1999 - 2026)

IONS vs AGI dividend yield comparison.

Year	IONS	AGI
2026	0.00%	0.26%
2025	0.00%	0.26%
2024	0.00%	0.54%
2023	0.00%	0.74%
2022	0.00%	0.99%
2021	0.00%	1.30%
2020	0.00%	0.74%
2019	0.00%	0.66%
2018	0.00%	0.56%
2017	0.00%	0.31%
2016	0.00%	0.29%
2015	0.00%	1.22%
2014	0.00%	2.81%
2013	0.00%	1.65%
2012	0.00%	1.14%
2011	0.00%	0.71%
2010	0.00%	0.34%
2000	4.85%	0.00%
1999	3.52%	0.00%