INVA vs TYRA

Comparison between Innoviva Inc (INVA, Company) and Tyra Biosciences Inc (TYRA, Company).

Both INVA and TYRA are from the Healthcare sector.

5-Year PerformanceINVA has outperformed TYRA, delivering a return of +4.8% compared to -0.8%

INVA vs TYRA - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	INVA(COMPANY)	TYRA(COMPANY)
Market Cap	$1.51B	$1.51B
Max Drawdown	84.32%	83.22%
Sharpe Ratio	0.21	1.65
5Y Beta	0.13	0.98
Industry	Biotechnology	Biotechnology
P/E Ratio	4.35	-9.68
Forward P/E	10.55	N/A
PEG Ratio	0.01	-0.33
5Y EPS CAGR	4.55%	N/A
Debt to Equity	20.96%	0.00%
Free Cash Flow Yield	12.53%	-7.28%

Market Cap

Winner

INVA

$1.51B

TYRA

$1.51B

Max Drawdown

INVA

84.32%

Winner

TYRA

83.22%

Sharpe Ratio

INVA

0.21

Winner

TYRA

1.65

5Y Beta

Winner

INVA

0.13

TYRA

0.98

Industry

INVA

Biotechnology

TYRA

Biotechnology

P/E Ratio

INVA

4.35

Winner

TYRA

-9.68

Forward P/E

INVA

10.55

TYRA

N/A

PEG Ratio

INVA

0.01

Winner

TYRA

-0.33

5Y EPS CAGR

INVA

4.55%

TYRA

N/A

Debt to Equity

INVA

20.96%

Winner

TYRA

0.00%

Free Cash Flow Yield

Winner

INVA

12.53%

TYRA

-7.28%

INVA vs TYRA - Historical Returns

Returns include dividend reinvestment.

Period	INVA	TYRA
1 month	-6.57%	-23.42%
3 months	-10.33%	-30.86%
6 months	-8.59%	-10.61%
1 year	+0.68%	+132.74%
5 years(CAGR)	+4.83%	-0.78%
10 years(CAGR)	+5.23%	N/A
Max(CAGR)	+1.96%	-0.78%

Winner

INVA

-6.57%

TYRA

-23.42%

Winner

INVA

-10.33%

TYRA

-30.86%

Winner

INVA

-8.59%

TYRA

-10.61%

INVA

+0.68%

Winner

TYRA

+132.74%

5Y(CAGR)

Winner

INVA

+4.83%

TYRA

-0.78%

10Y(CAGR)

INVA

+5.23%

TYRA

N/A

Max(CAGR)

Winner

INVA

+1.96%

TYRA

-0.78%

INVA vs TYRA - Annual Returns (2004 - 2026)

Returns include dividend reinvestment.

Year	INVA	TYRA
2026	+4.43%	-6.61%
2025	+14.89%	+82.19%
2024	+5.99%	-1.00%
2023	+20.87%	+95.90%
2022	-24.07%	-46.06%
2021	+38.22%	-45.88%
2020	-11.06%	N/A
2019	-18.15%	N/A
2018	+20.93%	N/A
2017	+27.38%	N/A
2016	+3.68%	N/A
2015	-20.54%	N/A
2014	-50.22%	N/A
2013	+58.87%	N/A
2012	+8.49%	N/A
2011	-13.91%	N/A
2010	+87.93%	N/A
2009	-7.50%	N/A
2008	-36.30%	N/A
2007	-37.82%	N/A
2006	+39.21%	N/A
2005	+26.87%	N/A
2004	-1.16%	N/A

INVA vs TYRA Drawdown Comparison

The maximum drawdown for INVA was -84.32%, occurring on Nov 21, 2008. Recovery took 1504 trading sessions.

The maximum drawdown for TYRA was -83.22%, occurring on Jun 17, 2022. Recovery took 1058 trading sessions.

The current INVA drawdown is -35.02%. The current TYRA drawdown is -36.83%.

Rank	INVA	TYRA
#1	-84.32% May 22, 2007 - May 13, 2013	-83.22% Nov 4, 2021 - Jan 27, 2026
#2	-78.77% Jul 11, 2013 - Sep 29, 2015	-48.23% Sep 15, 2021 - Nov 3, 2021
#3	-26.22% Apr 5, 2006 - Oct 19, 2006	-36.83% Apr 2, 2026 - Aug 13, 2026
#4	-21.77% Feb 8, 2007 - May 22, 2007	-13.45% Jan 29, 2026 - Feb 23, 2026
#5	-20.78% May 14, 2013 - Jul 11, 2013	-9.38% Mar 19, 2026 - Mar 31, 2026
#6	-16.58% Oct 21, 2004 - Mar 8, 2005	-5.74% Feb 25, 2026 - Mar 4, 2026
#7	-13.06% Oct 25, 2005 - Jan 17, 2006	-4.31% Mar 4, 2026 - Mar 11, 2026
#8	-12.25% Mar 8, 2005 - Jul 25, 2005	-1.48% Mar 11, 2026 - Mar 16, 2026
#9	-10.48% Feb 9, 2006 - Apr 5, 2006	-1.02% Jan 27, 2026 - Jan 29, 2026
#10	-8.88% Oct 27, 2006 - Jan 12, 2007	-0.05% Mar 31, 2026 - Apr 2, 2026
#11	-5.70% Oct 7, 2004 - Oct 21, 2004	N/A
#12	-5.63% Aug 1, 2005 - Sep 15, 2005	N/A
#13	-5.52% Jan 16, 2007 - Feb 7, 2007	N/A
#14	-4.40% Sep 20, 2005 - Oct 14, 2005	N/A
#15	-2.38% Feb 2, 2006 - Feb 8, 2006	N/A