INSM vs UTHR

Comparison between Insmed Inc (INSM, Company) and United Therapeutics Corp (UTHR, Company).

Both INSM and UTHR are from the Healthcare sector.

5-Year PerformanceINSM has outperformed UTHR, delivering a return of +32.3% compared to +24.7%

INSM vs UTHR - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	INSM(COMPANY)	UTHR(COMPANY)
Market Cap	$23B	$23B
Max Drawdown	98.65%	93.18%
Sharpe Ratio	0.47	1.50
5Y Beta	0.77	0.41
Industry	Biotechnology	Drug Manufacturers - Specialty & Generic
P/E Ratio	-19.27	18.48
Forward P/E	16.37	19.88
PEG Ratio	1.09	1.96
5Y EPS CAGR	12.24%	26.56%
Debt to Equity	76.93%	0.00%
Free Cash Flow Yield	-3.98%	4.41%
P/S Ratio	29.52	7.33
P/B Ratio	32.90	3.90

Market Cap

Winner

INSM

$23B

UTHR

$23B

Max Drawdown

INSM

98.65%

Winner

UTHR

93.18%

Sharpe Ratio

INSM

0.47

Winner

UTHR

1.50

5Y Beta

INSM

0.77

Winner

UTHR

0.41

Industry

INSM

Biotechnology

UTHR

Drug Manufacturers - Specialty & Generic

P/E Ratio

Winner

INSM

-19.27

UTHR

18.48

Forward P/E

Winner

INSM

16.37

UTHR

19.88

PEG Ratio

Winner

INSM

1.09

UTHR

1.96

5Y EPS CAGR

INSM

12.24%

Winner

UTHR

26.56%

Debt to Equity

INSM

76.93%

Winner

UTHR

0.00%

Free Cash Flow Yield

INSM

-3.98%

Winner

UTHR

4.41%

P/S Ratio

INSM

29.52

Winner

UTHR

7.33

P/B Ratio

INSM

32.90

Winner

UTHR

3.90

INSM vs UTHR - Historical Returns

Returns include dividend reinvestment.

Period	INSM	UTHR
1 month	+19.83%	+3.49%
3 months	-30.79%	-0.35%
6 months	-35.89%	+11.91%
1 year	+16.39%	+94.12%
5 years(CAGR)	+32.29%	+24.70%
10 years(CAGR)	+26.90%	+17.80%
Max(CAGR)	-1.44%	+14.15%

Winner

INSM

+19.83%

UTHR

+3.49%

INSM

-30.79%

Winner

UTHR

-0.35%

INSM

-35.89%

Winner

UTHR

+11.91%

INSM

+16.39%

Winner

UTHR

+94.12%

5Y(CAGR)

Winner

INSM

+32.29%

UTHR

+24.70%

10Y(CAGR)

Winner

INSM

+26.90%

UTHR

+17.80%

Max(CAGR)

INSM

-1.44%

Winner

UTHR

+14.15%

INSM vs UTHR - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	INSM	UTHR
2026	-36.29%	+13.48%
2025	+148.81%	+35.26%
2024	+130.59%	+55.20%
2023	+61.57%	-19.55%
2022	-28.97%	+32.03%
2021	-18.49%	+40.37%
2020	+40.70%	+73.16%
2019	+70.94%	-18.18%
2018	-59.58%	-28.33%
2017	+138.38%	+2.75%
2016	-23.26%	-7.79%
2015	+13.72%	+22.61%
2014	-9.74%	+16.76%
2013	+144.25%	+110.07%
2012	+112.38%	+11.71%
2011	-52.34%	-26.58%
2010	-18.08%	+18.30%
2009	+57.14%	+64.25%
2008	-43.67%	-36.88%
2007	-8.33%	+83.48%
2006	-58.69%	-20.62%
2005	-14.35%	+56.91%
2004	-27.43%	+92.29%
2003	+518.75%	+34.21%
2002	-88.60%	+62.93%
2001	+1.87%	-26.33%
2000	-78.95%	-72.24%
1999	N/A	+39.39%

INSM vs UTHR Drawdown Comparison

The maximum drawdown for INSM was -98.65%, occurring on Nov 25, 2011. Recovery took 6341 trading sessions.

The maximum drawdown for UTHR was -93.18%, occurring on Dec 10, 2001. Recovery took 2635 trading sessions.

The current INSM drawdown is -46.63%. The current UTHR drawdown is -5.54%.

Rank	INSM	UTHR
#1	-98.65% Aug 30, 2000 - Nov 17, 2025	-93.18% Jul 12, 2000 - Jan 3, 2011
#2	-56.54% Dec 1, 2025 - Jun 10, 2026	-60.30% Apr 23, 2015 - Apr 1, 2021
#3	-35.29% Jun 5, 2000 - Aug 3, 2000	-60.19% Feb 25, 2000 - Jun 29, 2000
#4	-28.69% Aug 3, 2000 - Aug 28, 2000	-47.37% Apr 27, 2011 - Jul 22, 2013
#5	-2.91% Jun 1, 2000 - Jun 5, 2000	-33.00% Nov 8, 2024 - Sep 19, 2025
#6	-2.36% Nov 19, 2025 - Nov 24, 2025	-26.83% Dec 9, 2022 - Jun 12, 2024
#7	-2.16% Nov 25, 2025 - Dec 1, 2025	-24.78% Dec 23, 2013 - Sep 2, 2014
#8	N/A	-23.10% Dec 31, 2021 - May 24, 2022
#9	N/A	-19.74% Jan 20, 2000 - Feb 8, 2000
#10	N/A	-19.68% Nov 11, 1999 - Dec 30, 1999
#11	N/A	-19.56% Apr 21, 2021 - Aug 6, 2021
#12	N/A	-16.74% Jul 8, 2022 - Nov 2, 2022
#13	N/A	-14.22% Aug 31, 2021 - Dec 29, 2021
#14	N/A	-10.64% Feb 25, 2026 - Mar 10, 2026
#15	N/A	-10.32% Sep 24, 2014 - Jan 15, 2015