INO vs SPY
Comparison between Inovio Pharmaceuticals Inc (INO, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).
5-Year PerformanceSPY has outperformed INO, delivering a return of +13.3% compared to -59.2%
INO vs SPY - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
INO vs SPY - Historical Returns
Returns include dividend reinvestment.
INO vs SPY - Annual Returns (1999 - 2026)
Returns include dividend reinvestment.
| Year | INO | SPY |
|---|---|---|
| 2026 | -36.69% | +8.26% |
| 2025 | -4.40% | +18.00% |
| 2024 | -72.96% | +25.59% |
| 2023 | -66.45% | +26.72% |
| 2022 | -70.00% | -18.64% |
| 2021 | -48.72% | +30.52% |
| 2020 | +175.70% | +17.28% |
| 2019 | -21.80% | +31.09% |
| 2018 | -14.53% | -5.24% |
| 2017 | -41.58% | +20.78% |
| 2016 | +8.44% | +13.59% |
| 2015 | -27.90% | +1.31% |
| 2014 | -20.03% | +14.56% |
| 2013 | +476.31% | +29.00% |
| 2012 | +14.83% | +14.17% |
| 2011 | -63.73% | +0.85% |
| 2010 | +4.55% | +13.14% |
| 2009 | +119.23% | +22.67% |
| 2008 | -44.68% | -36.25% |
| 2007 | -72.04% | +5.32% |
| 2006 | +34.29% | +13.85% |
| 2005 | -41.79% | +5.32% |
| 2004 | -29.14% | +10.75% |
| 2003 | +346.43% | +24.18% |
| 2002 | -58.46% | -22.42% |
| 2001 | -31.73% | -10.13% |
| 2000 | -72.22% | -8.84% |
| 1999 | +4.00% | +8.61% |
INO vs SPY Drawdown Comparison
The maximum drawdown for INO was -99.95%, occurring on Apr 7, 2026. This drawdown has not yet recovered.
The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.
The current INO drawdown is -99.95%. The current SPY drawdown is -2.90%.
| Rank | INO | SPY |
|---|---|---|
| #1 | -99.95% Mar 3, 2000 - Apr 7, 2026 | -55.20% Oct 9, 2007 - Aug 16, 2012 |
| #2 | -38.67% Feb 17, 2000 - Mar 3, 2000 | -47.50% Mar 24, 2000 - Oct 26, 2006 |
| #3 | -22.72% Jan 11, 2000 - Feb 3, 2000 | -33.70% Feb 19, 2020 - Aug 10, 2020 |
| #4 | -14.29% Dec 21, 1999 - Jan 11, 2000 | -24.50% Jan 3, 2022 - Dec 13, 2023 |
| #5 | -12.00% Nov 1, 1999 - Dec 21, 1999 | -19.34% Sep 20, 2018 - Apr 12, 2019 |
| #6 | -10.12% Feb 8, 2000 - Feb 14, 2000 | -18.76% Feb 19, 2025 - Jun 26, 2025 |
| #7 | -4.36% Feb 3, 2000 - Feb 8, 2000 | -13.02% Jul 20, 2015 - Apr 18, 2016 |
| #8 | N/A | -10.10% Jan 26, 2018 - Aug 6, 2018 |
| #9 | N/A | -9.44% Sep 2, 2020 - Nov 11, 2020 |
| #10 | N/A | -9.30% Jan 19, 2000 - Mar 17, 2000 |
| #11 | N/A | -9.05% Jul 19, 2007 - Oct 5, 2007 |
| #12 | N/A | -8.88% Jan 27, 2026 - Apr 14, 2026 |
| #13 | N/A | -8.41% Jul 16, 2024 - Sep 19, 2024 |
| #14 | N/A | -7.35% Sep 14, 2012 - Jan 2, 2013 |
| #15 | N/A | -7.27% Sep 18, 2014 - Oct 31, 2014 |
Correlation
Correlation between INO and SPY is -0.31 which considered as a weak negative correlation - the stocks show a slight tendency to move in opposite directions.
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