INO vs ACHL

Comparison between Inovio Pharmaceuticals Inc (INO, Company) and Achilles Therapeutics Plc (ACHL, Company).

Both INO and ACHL are from the Healthcare sector.

5-Year PerformanceACHL has outperformed INO, delivering a return of -25.5% compared to -61.8%

INO vs ACHL - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	INO(COMPANY)	ACHL(COMPANY)
Market Cap	$63M	$63M
Max Drawdown	99.97%	96.08%
Sharpe Ratio	-0.12	1.40
5Y Beta	0.94	0.11
Industry	Biotechnology	Biotechnology
P/E Ratio	-0.67	N/A
Forward P/E	16.58	N/A
PEG Ratio	0.00	N/A
5Y EPS CAGR	-32.16%	N/A
Debt to Equity	0.00%	N/A
P/S Ratio	961.51	N/A
P/B Ratio	12.54	0.61

Market Cap

Winner

INO

$63M

ACHL

$63M

Max Drawdown

INO

99.97%

Winner

ACHL

96.08%

Sharpe Ratio

INO

-0.12

Winner

ACHL

1.40

5Y Beta

INO

0.94

Winner

ACHL

0.11

Industry

INO

Biotechnology

ACHL

Biotechnology

P/E Ratio

INO

-0.67

ACHL

N/A

Forward P/E

INO

16.58

ACHL

N/A

PEG Ratio

INO

0.00

ACHL

N/A

5Y EPS CAGR

INO

-32.16%

ACHL

N/A

Debt to Equity

INO

0.00%

ACHL

N/A

P/S Ratio

INO

961.51

ACHL

N/A

P/B Ratio

INO

12.54

Winner

ACHL

0.61

INO vs ACHL - Historical Returns

Returns include dividend reinvestment.

Period	INO	ACHL
1 month	-22.41%	+0.00%
3 months	-32.83%	+0.00%
6 months	-44.09%	+0.00%
1 year	-47.05%	+0.00%
5 years(CAGR)	-61.81%	-25.51%
10 years(CAGR)	-38.00%	N/A
Max(CAGR)	-21.56%	-36.22%

INO

-22.41%

Winner

ACHL

+0.00%

INO

-32.83%

Winner

ACHL

+0.00%

INO

-44.09%

Winner

ACHL

+0.00%

INO

-47.05%

Winner

ACHL

+0.00%

5Y(CAGR)

INO

-61.81%

Winner

ACHL

-25.51%

10Y(CAGR)

INO

-38.00%

ACHL

N/A

Max(CAGR)

Winner

INO

-21.56%

ACHL

-36.22%

INO vs ACHL - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	INO	ACHL
2026	-46.74%	+0.00%
2025	-4.40%	+29.81%
2024	-72.96%	+30.73%
2023	-66.45%	-15.33%
2022	-70.00%	-82.79%
2021	-48.72%	-69.73%
2020	+175.70%	N/A
2019	-21.80%	N/A
2018	-14.53%	N/A
2017	-41.58%	N/A
2016	+8.44%	N/A
2015	-27.90%	N/A
2014	-20.03%	N/A
2013	+476.31%	N/A
2012	+14.83%	N/A
2011	-63.73%	N/A
2010	+4.55%	N/A
2009	+119.23%	N/A
2008	-44.68%	N/A
2007	-72.04%	N/A
2006	+34.29%	N/A
2005	-41.79%	N/A
2004	-29.14%	N/A
2003	+346.43%	N/A
2002	-58.46%	N/A
2001	-31.73%	N/A
2000	-72.22%	N/A
1999	+4.00%	N/A

INO vs ACHL Drawdown Comparison

The maximum drawdown for INO was -99.97%, occurring on Jul 30, 2026. This drawdown has not yet recovered.

The maximum drawdown for ACHL was -96.08%, occurring on Sep 11, 2024. This drawdown has not yet recovered.

The current INO drawdown is -99.96%. The current ACHL drawdown is -91.71%.

Rank	INO	ACHL
#1	-99.97% Mar 3, 2000 - Jul 30, 2026	-96.08% Apr 6, 2021 - Sep 11, 2024
#2	-38.67% Feb 17, 2000 - Mar 3, 2000	-9.85% Mar 31, 2021 - Apr 6, 2021
#3	-22.72% Jan 11, 2000 - Feb 3, 2000	N/A
#4	-14.29% Dec 21, 1999 - Jan 11, 2000	N/A
#5	-12.00% Nov 1, 1999 - Dec 21, 1999	N/A
#6	-10.12% Feb 8, 2000 - Feb 14, 2000	N/A
#7	-4.36% Feb 3, 2000 - Feb 8, 2000	N/A