IDNA vs SIXL

Comparison between ISHARES GENOMICS IMMUNOLOGY AND HEALTHCARE ETF (IDNA, ETF) and ETC 6 MERIDIAN LOW BETA EQUITY STRATEGY ETF (SIXL, ETF).

5-Year PerformanceSIXL has outperformed IDNA, delivering a return of +4.8% compared to -7.2%

IDNA vs SIXL - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	IDNA(ETF)	SIXL(ETF)
Net Assets	$194M	$193M
Expense Ratio	0.47%	0.46%
Max Drawdown	68.69%	16.90%
Sharpe Ratio	1.75	0.75
5Y Beta	0.86	0.33
P/E Ratio	-18.14	18.32
Forward P/E	N/A	16.45
5Y Dividends CAGR	20.32%	36.89%
5Y EPS CAGR	N/A	11.36%
Debt to Equity	10.39%	52.73%
P/S Ratio	8.75	1.59
P/B Ratio	3.79	2.41

Net Assets

Winner

IDNA

$194M

SIXL

$193M

Expense Ratio

IDNA

0.47%

Winner

SIXL

0.46%

Max Drawdown

IDNA

68.69%

Winner

SIXL

16.90%

Sharpe Ratio

Winner

IDNA

1.75

SIXL

0.75

5Y Beta

IDNA

0.86

Winner

SIXL

0.33

P/E Ratio

Winner

IDNA

-18.14

SIXL

18.32

Forward P/E

IDNA

N/A

SIXL

16.45

5Y Dividends CAGR

IDNA

20.32%

Winner

SIXL

36.89%

5Y EPS CAGR

IDNA

N/A

SIXL

11.36%

Debt to Equity

Winner

IDNA

10.39%

SIXL

52.73%

P/S Ratio

IDNA

8.75

Winner

SIXL

1.59

P/B Ratio

IDNA

3.79

Winner

SIXL

2.41

IDNA vs SIXL - Holdings Comparison

IDNA and SIXL have 2 common holdings. Overlap is 0.17%

IDNA's top 25 holdings weight is 85.74%. SIXL's top 25 holdings weight is 14.33%.

Rank	IDNA	SIXL
#1	REVOLUTION MEDICINES INC ORDINARY SHARES (RVMD) - 7.00%	TG THERAPEUTICS INC (TGTX) - 0.76%
#2	MODERNA INC (MRNA) - 6.44%	CORECIVIC INC (CXW) - 0.70%
#3	IPSEN SA (n/a) - 5.17%	PROGYNY INC (PGNY) - 0.69%
#4	TAKEDA PHARMACEUTICAL CO LTD (n/a) - 4.43%	DAVITA INC (DVA) - 0.63%
#5	MERCK & CO INC (MRK) - 4.27%	VIRTU FINANCIAL INC CLASS A (VIRT) - 0.62%
#6	BAYER AG (n/a) - 4.25%	THE CHEFS' WAREHOUSE INC (CHEF) - 0.62%
#7	GSK PLC (n/a) - 4.03%	JOHN WILEY & SONS INC CLASS A (WLY) - 0.61%
#8	ROCHE HOLDING AG ORDINARY SHARES NEW (n/a) - 3.94%	ELEVANCE HEALTH INC (ELV) - 0.60%
#9	BIONTECH SE ADR (BNTX) - 3.89%	UNITED FIRE GROUP INC (UFCS) - 0.58%
#10	EXELIXIS INC (EXEL) - 3.75%	EZCORP INC REGISTERED SHS -A- NON VTG (EZPW) - 0.58%
#11	REGENERON PHARMACEUTICALS INC (REGN) - 3.72%	PROTAGONIST THERAPEUTICS INC (PTGX) - 0.57%
#12	TWIST BIOSCIENCE CORP (TWST) - 3.62%	PRICESMART INC (PSMT) - 0.55%
#13	INCYTE CORP (INCY) - 3.57%	CVS HEALTH CORP (CVS) - 0.55%
#14	VERTEX PHARMACEUTICALS INC (VRTX) - 3.56%	MURPHY USA INC (MUSA) - 0.55%
#15	SANOFI SA (n/a) - 3.28%	SENSIENT TECHNOLOGIES CORP (SXT) - 0.54%
#16	GENMAB AS (n/a) - 3.18%	EXELIXIS INC (EXEL) - 0.54%
#17	IMMUNITYBIO INC ORDINARY SHARES (IBRX) - 2.72%	MONSTER BEVERAGE CORP (MNST) - 0.53%
#18	IDEAYA BIOSCIENCES INC (IDYA) - 2.68%	n/a (INDV) - 0.52%
#19	CARIS LIFE SCIENCES INC (CAI) - 2.38%	WHITESTONE REIT (WSR) - 0.52%
#20	ARCUS BIOSCIENCES INC (RCUS) - 2.16%	EMPLOYERS HOLDINGS INC (EIG) - 0.52%
#21	ONO PHARMACEUTICAL CO LTD (n/a) - 1.95%	n/a (HRMY) - 0.52%
#22	CRISPR THERAPEUTICS AG (CRSP) - 1.84%	NATIONAL HEALTHCARE CORP (NHC) - 0.52%
#23	IOVANCE BIOTHERAPEUTICS INC (IOVA) - 1.42%	n/a (MSGS) - 0.51%
#24	NOVAVAX INC (NVAX) - 1.32%	MAPLEBEAR INC (CART) - 0.50%
#25	n/a (NUVB) - 1.17%	NEWMARKET CORP (NEU) - 0.50%
Total Holdings	76	242

IDNA vs SIXL - Historical Returns

Returns include dividend reinvestment.

Period	IDNA	SIXL
1 month	+6.97%	+4.89%
3 months	+6.97%	+3.58%
6 months	+11.79%	+5.68%
1 year	+55.69%	+11.23%
5 years(CAGR)	-7.18%	+4.83%
Max(CAGR)	+4.84%	+8.84%

Winner

IDNA

+6.97%

SIXL

+4.89%

Winner

IDNA

+6.97%

SIXL

+3.58%

Winner

IDNA

+11.79%

SIXL

+5.68%

Winner

IDNA

+55.69%

SIXL

+11.23%

5Y(CAGR)

IDNA

-7.18%

Winner

SIXL

+4.83%

Max(CAGR)

IDNA

+4.84%

Winner

SIXL

+8.84%

IDNA vs SIXL - Annual Returns (2019 - 2026)

Returns include dividend reinvestment.

Year	IDNA	SIXL
2026	+25.77%	+9.47%
2025	+16.60%	+0.14%
2024	-2.34%	+13.42%
2023	-7.24%	+2.15%
2022	-42.36%	-7.19%
2021	-4.55%	+20.72%
2020	+55.62%	+18.42%
2019	+20.82%	N/A

IDNA vs SIXL Drawdown Comparison

The maximum drawdown for IDNA was -68.26%, occurring on Oct 27, 2023. This drawdown has not yet recovered.

The maximum drawdown for SIXL was -16.07%, occurring on Oct 7, 2022. Recovery took 591 trading sessions.

The current IDNA drawdown is -37.89%. The current SIXL drawdown is -1.10%.

Rank	IDNA	SIXL
#1	-68.26% Sep 2, 2021 - Oct 27, 2023	-16.07% Dec 31, 2021 - May 9, 2024
#2	-26.93% Mar 4, 2020 - Apr 17, 2020	-11.65% Nov 29, 2024 - Feb 5, 2026
#3	-22.23% Feb 8, 2021 - Aug 9, 2021	-7.53% Jun 8, 2020 - Jul 29, 2020
#4	-14.38% Jul 18, 2019 - Nov 20, 2019	-7.12% Aug 7, 2020 - Oct 12, 2020
#5	-13.58% Jul 20, 2020 - Oct 9, 2020	-6.52% Mar 2, 2026 - Jul 2, 2026
#6	-9.93% Oct 13, 2020 - Nov 27, 2020	-5.84% Oct 12, 2020 - Nov 11, 2020
#7	-9.34% Dec 24, 2019 - Mar 4, 2020	-5.82% Feb 12, 2021 - Mar 15, 2021
#8	-8.30% Dec 22, 2020 - Jan 14, 2021	-5.20% Nov 16, 2021 - Dec 22, 2021
#9	-7.52% Aug 9, 2021 - Sep 2, 2021	-5.13% Sep 2, 2021 - Nov 5, 2021
#10	-7.36% May 18, 2020 - Jun 22, 2020	-3.96% May 11, 2020 - May 26, 2020
#11	-6.03% Apr 27, 2020 - May 7, 2020	-3.54% May 16, 2024 - Jul 12, 2024
#12	-4.87% Jan 19, 2021 - Feb 2, 2021	-3.44% Jul 30, 2024 - Aug 16, 2024
#13	-4.19% May 11, 2020 - May 18, 2020	-2.88% Apr 23, 2021 - Jun 7, 2021
#14	-3.85% Jun 19, 2019 - Jun 28, 2019	-2.88% Mar 15, 2021 - Apr 1, 2021
#15	-3.70% Jun 23, 2020 - Jul 8, 2020	-2.87% Jan 26, 2021 - Feb 5, 2021

Correlation

Correlation between IDNA and SIXL is -0.34 which considered as a weak negative correlation - the stocks show a slight tendency to move in opposite directions.

-0.34

-101