HPE vs ALNY

Comparison between Hewlett Packard Enterprise Company (HPE, Company) and Alnylam Pharmaceuticals Inc (ALNY, Company).

HPE is from the Technology sector, while ALNY is from the Healthcare sector.

5-Year PerformanceALNY has outperformed HPE, delivering a return of +17.6% compared to +17.0%

HPE vs ALNY - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	HPE(COMPANY)	ALNY(COMPANY)
Market Cap	$40B	$40B
Max Drawdown	68.40%	83.58%
Sharpe Ratio	1.81	0.26
5Y Beta	1.59	0.81
Industry	Communication Equipment	Biotechnology
P/E Ratio	-312.90	128.05
Forward P/E	12.47	31.95
PEG Ratio	0.85	0.51
Dividend Yield	1.79%	N/A
5Y Dividends CAGR	2.57%	N/A
5Y EPS CAGR	-22.17%	N/A
Debt to Equity	83.86%	0.00%
Free Cash Flow Yield	11.12%	1.16%
P/S Ratio	1.13	9.44
P/B Ratio	1.61	37.38

Market Cap

Winner

HPE

$40B

ALNY

$40B

Max Drawdown

Winner

HPE

68.40%

ALNY

83.58%

Sharpe Ratio

Winner

HPE

1.81

ALNY

0.26

5Y Beta

HPE

1.59

Winner

ALNY

0.81

Industry

HPE

Communication Equipment

ALNY

Biotechnology

P/E Ratio

Winner

HPE

-312.90

ALNY

128.05

Forward P/E

Winner

HPE

12.47

ALNY

31.95

PEG Ratio

HPE

0.85

Winner

ALNY

0.51

Dividend Yield

HPE

1.79%

ALNY

N/A

5Y Dividends CAGR

HPE

2.57%

ALNY

N/A

5Y EPS CAGR

HPE

-22.17%

ALNY

N/A

Debt to Equity

HPE

83.86%

Winner

ALNY

0.00%

Free Cash Flow Yield

Winner

HPE

11.12%

ALNY

1.16%

P/S Ratio

Winner

HPE

1.13

ALNY

9.44

P/B Ratio

Winner

HPE

1.61

ALNY

37.38

HPE vs ALNY - Historical Returns

Returns include dividend reinvestment.

Period	HPE	ALNY
1 month	+25.42%	-9.84%
3 months	+31.81%	-7.80%
6 months	+35.18%	-33.35%
1 year	+90.26%	+14.21%
5 years(CAGR)	+17.04%	+17.57%
10 years(CAGR)	+16.11%	+17.71%
Max(CAGR)	+14.81%	+18.60%

Winner

HPE

+25.42%

ALNY

-9.84%

Winner

HPE

+31.81%

ALNY

-7.80%

Winner

HPE

+35.18%

ALNY

-33.35%

Winner

HPE

+90.26%

ALNY

+14.21%

5Y(CAGR)

HPE

+17.04%

Winner

ALNY

+17.57%

10Y(CAGR)

HPE

+16.11%

Winner

ALNY

+17.71%

Max(CAGR)

HPE

+14.81%

Winner

ALNY

+18.60%

HPE vs ALNY - Annual Returns (2004 - 2026)

Returns include dividend reinvestment.

Year	HPE	ALNY
2026	+30.40%	-26.27%
2025	+14.86%	+70.21%
2024	+29.45%	+20.72%
2023	+9.00%	-18.06%
2022	+2.10%	+36.65%
2021	+40.71%	+32.38%
2020	-23.44%	+12.41%
2019	+21.44%	+58.29%
2018	-7.25%	-44.70%
2017	+7.52%	+228.80%
2016	+54.71%	-59.75%
2015	-7.83%	-3.71%
2014	N/A	+51.89%
2013	N/A	+235.42%
2012	N/A	+110.74%
2011	N/A	-18.58%
2010	N/A	-45.64%
2009	N/A	-29.94%
2008	N/A	-14.49%
2007	N/A	+34.82%
2006	N/A	+65.12%
2005	N/A	+76.25%
2004	N/A	+6.71%

HPE vs ALNY Drawdown Comparison

The maximum drawdown for HPE was -56.91%, occurring on Mar 23, 2020. Recovery took 969 trading sessions.

The maximum drawdown for ALNY was -83.58%, occurring on Oct 3, 2011. Recovery took 1443 trading sessions.

The current ALNY drawdown is -39.94%.

Rank	HPE	ALNY
#1	-56.91% Mar 6, 2018 - Jan 7, 2022	-83.58% Oct 9, 2007 - Jul 3, 2013
#2	-48.36% Jan 22, 2025 - Sep 10, 2025	-77.36% Jun 22, 2015 - Nov 10, 2017
#3	-30.59% Mar 29, 2022 - Jun 15, 2023	-57.81% Mar 20, 2018 - Jun 19, 2020
#4	-28.81% Oct 23, 2015 - Mar 16, 2016	-52.18% Jun 9, 2004 - Jan 6, 2005
#5	-26.28% Jun 18, 2024 - Nov 8, 2024	-47.61% Jan 13, 2014 - Oct 24, 2014
#6	-23.73% Oct 9, 2025 - Apr 17, 2026	-42.46% Oct 14, 2021 - Aug 3, 2022
#7	-16.52% Aug 8, 2023 - Mar 5, 2024	-40.61% Dec 21, 2022 - Jun 26, 2024
#8	-14.84% Apr 1, 2016 - May 31, 2016	-39.94% Oct 20, 2025 - May 8, 2026
#9	-14.03% Dec 6, 2024 - Jan 22, 2025	-36.52% Mar 29, 2006 - Oct 31, 2006
#10	-13.43% May 16, 2017 - Sep 26, 2017	-36.33% Dec 8, 2006 - Jul 11, 2007
#11	-12.96% Jun 21, 2016 - Jul 14, 2016	-34.67% Sep 12, 2005 - Jan 10, 2006
#12	-12.64% Feb 16, 2022 - Mar 25, 2022	-32.55% Jan 10, 2005 - Sep 7, 2005
#13	-12.49% Oct 2, 2017 - Dec 18, 2017	-26.79% Jan 25, 2021 - Jun 18, 2021
#14	-11.76% Mar 6, 2024 - Jun 5, 2024	-26.77% Jul 20, 2020 - Jan 12, 2021
#15	-11.37% Jan 29, 2018 - Feb 23, 2018	-25.36% Oct 16, 2024 - May 30, 2025