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HOWL vs AYTU

Comparison between Werewolf Therapeutics Inc (HOWL, Company) and Aytu BioPharma Inc (AYTU, Company).

Both HOWL and AYTU are from the Healthcare sector.

5-Year PerformanceHOWL has outperformed AYTU, delivering a return of -51.8% compared to -51.8%

HOWL vs AYTU - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap
Winner
HOWL
$22M
AYTU
$22M
Max Drawdown
Winner
HOWL
98.48%
AYTU
100.00%
Sharpe Ratio
HOWL
-0.60
Winner
AYTU
-0.23
5Y Beta
HOWL
2.05
Winner
AYTU
0.00
Industry
HOWL
Biotechnology
AYTU
Drug Manufacturers - Specialty & Generic
P/E Ratio
HOWL
-0.39
Winner
AYTU
-0.59
Forward P/E
HOWL
N/A
AYTU
25.77
5Y EPS CAGR
HOWL
N/A
AYTU
-32.17%
Debt to Equity
HOWL
262.95%
Winner
AYTU
32.46%
Free Cash Flow Yield
HOWL
N/A
AYTU
6.42%

HOWL vs AYTU - Historical Returns

Returns include dividend reinvestment.

1M
Winner
HOWL
+49.35%
AYTU
-5.02%
3M
HOWL
-32.35%
Winner
AYTU
-17.46%
6M
HOWL
-36.52%
Winner
AYTU
-19.38%
1Y
HOWL
-64.62%
Winner
AYTU
-18.11%
5Y(CAGR)
Winner
HOWL
-51.80%
AYTU
-51.83%
10Y(CAGR)
HOWL
N/A
AYTU
-67.14%
Max(CAGR)
Winner
HOWL
-49.22%
AYTU
-67.14%

HOWL vs AYTU - Annual Returns (2017 - 2026)

Returns include dividend reinvestment.

YearHOWLAYTU
2026-28.66%-24.91%
2025-59.39%+52.76%
2024-68.10%-41.18%
2023+88.29%-28.03%
2022-83.22%-87.81%
2021-26.02%-78.33%
2020N/A-42.50%
2019N/A+21.23%
2018N/A-98.28%
2017N/A-88.85%

HOWL vs AYTU Drawdown Comparison

The maximum drawdown for HOWL was -98.48%, occurring on Jun 29, 2026. This drawdown has not yet recovered.

The maximum drawdown for AYTU was -100.00%, occurring on Apr 7, 2025. This drawdown has not yet recovered.

The current HOWL drawdown is -97.74%. The current AYTU drawdown is -100.00%.

RankHOWLAYTU
#1-98.48%
Jul 2, 2021 - Jun 29, 2026
-100.00%
Feb 8, 2017 - Apr 7, 2025
#2-28.66%
May 3, 2021 - Jun 30, 2021
-11.00%
Feb 1, 2017 - Feb 8, 2017

Correlation

Correlation between HOWL and AYTU is 0.88 which considered as a strong positive correlation - the stocks tend to move together.

0.88
-101

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