HCM vs ZBIO

Comparison between HUTCHMED (China) Ltd (HCM, Company) and Zenas Biopharma Inc (ZBIO, Company).

Both HCM and ZBIO are from the Healthcare sector.

HCM vs ZBIO - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	HCM(COMPANY)	ZBIO(COMPANY)
Market Cap	$1.98B	$1.99B
Max Drawdown	82.18%	74.96%
Sharpe Ratio	-1.05	1.20
5Y Beta	0.75	1.24
Industry	Drug Manufacturers - Specialty & Generic	Biotechnology
P/E Ratio	4.34	-3.90
Forward P/E	13.00	N/A
PEG Ratio	0.00	N/A
Debt to Equity	7.53%	0.00%
Free Cash Flow Yield	-3.97%	-10.59%
P/S Ratio	3.66	85.70
P/B Ratio	1.59	5.91

Market Cap

HCM

$1.98B

Winner

ZBIO

$1.99B

Max Drawdown

HCM

82.18%

Winner

ZBIO

74.96%

Sharpe Ratio

HCM

-1.05

Winner

ZBIO

1.20

5Y Beta

Winner

HCM

0.75

ZBIO

1.24

Industry

HCM

Drug Manufacturers - Specialty & Generic

ZBIO

Biotechnology

P/E Ratio

HCM

4.34

Winner

ZBIO

-3.90

Forward P/E

HCM

13.00

ZBIO

N/A

PEG Ratio

HCM

0.00

ZBIO

N/A

Debt to Equity

HCM

7.53%

Winner

ZBIO

0.00%

Free Cash Flow Yield

Winner

HCM

-3.97%

ZBIO

-10.59%

P/S Ratio

Winner

HCM

3.66

ZBIO

85.70

P/B Ratio

Winner

HCM

1.59

ZBIO

5.91

HCM vs ZBIO - Historical Returns

Returns include dividend reinvestment.

Period	HCM	ZBIO
1 month	+1.55%	+21.63%
3 months	-11.91%	+54.44%
6 months	-22.07%	+47.57%
1 year	-34.00%	+104.90%
5 years(CAGR)	-22.36%	N/A
10 years(CAGR)	-0.96%	N/A
Max(CAGR)	-1.19%	+35.27%

HCM

+1.55%

Winner

ZBIO

+21.63%

HCM

-11.91%

Winner

ZBIO

+54.44%

HCM

-22.07%

Winner

ZBIO

+47.57%

HCM

-34.00%

Winner

ZBIO

+104.90%

5Y(CAGR)

HCM

-22.36%

ZBIO

N/A

10Y(CAGR)

HCM

-0.96%

ZBIO

N/A

Max(CAGR)

HCM

-1.19%

Winner

ZBIO

+35.27%

HCM vs ZBIO - Annual Returns (2016 - 2026)

Returns include dividend reinvestment.

Year	HCM	ZBIO
2026	-13.33%	-6.75%
2025	-11.60%	+303.00%
2024	-17.70%	-54.88%
2023	+10.56%	N/A
2022	-58.54%	N/A
2021	+3.06%	N/A
2020	+21.15%	N/A
2019	+9.96%	N/A
2018	-43.87%	N/A
2017	+163.68%	N/A
2016	+1.27%	N/A

HCM vs ZBIO Drawdown Comparison

The maximum drawdown for HCM was -82.18%, occurring on Oct 25, 2022. This drawdown has not yet recovered.

The maximum drawdown for ZBIO was -74.96%, occurring on Jan 28, 2025. Recovery took 240 trading sessions.

The current HCM drawdown is -72.45%. The current ZBIO drawdown is -25.48%.

Rank	HCM	ZBIO
#1	-82.18% Aug 9, 2021 - Oct 25, 2022	-74.96% Oct 22, 2024 - Oct 8, 2025
#2	-63.07% Jan 2, 2018 - Jul 21, 2021	-64.79% Dec 24, 2025 - Jan 6, 2026
#3	-20.59% Jun 15, 2016 - Dec 2, 2016	-19.71% Dec 12, 2025 - Dec 22, 2025
#4	-14.78% Jan 3, 2017 - Mar 13, 2017	-14.88% Nov 26, 2025 - Dec 12, 2025
#5	-14.57% Nov 16, 2017 - Dec 22, 2017	-13.92% Oct 9, 2025 - Oct 27, 2025
#6	-14.55% Aug 8, 2017 - Oct 2, 2017	-12.01% Sep 24, 2024 - Oct 15, 2024
#7	-13.03% Jul 22, 2021 - Jul 30, 2021	-11.92% Oct 27, 2025 - Nov 6, 2025
#8	-12.01% Oct 11, 2017 - Oct 27, 2017	-6.22% Nov 19, 2025 - Nov 24, 2025
#9	-11.04% Mar 30, 2017 - May 17, 2017	-3.47% Sep 13, 2024 - Sep 20, 2024
#10	-10.72% May 6, 2016 - Jun 8, 2016	-3.39% Nov 7, 2025 - Nov 11, 2025
#11	-9.17% Dec 6, 2016 - Jan 3, 2017	-2.23% Nov 12, 2025 - Nov 17, 2025
#12	-8.91% Mar 15, 2017 - Mar 30, 2017	-2.16% Sep 20, 2024 - Sep 24, 2024
#13	-7.54% Apr 20, 2016 - May 6, 2016	-1.27% Oct 15, 2024 - Oct 17, 2024
#14	-7.09% Oct 27, 2017 - Nov 15, 2017	-0.56% Oct 17, 2024 - Oct 21, 2024
#15	-6.74% Jul 5, 2017 - Aug 3, 2017	N/A

Correlation

Correlation between HCM and ZBIO is -0.36 which considered as a weak negative correlation - the stocks show a slight tendency to move in opposite directions.

-0.36

-101