GYRE vs SPIR

Comparison between Gyre Therapeutics Inc (GYRE, Company) and Spire Global Inc - Class A (SPIR, Company).

GYRE is from the Healthcare sector, while SPIR is from the Industrials sector.

5-Year PerformanceGYRE has outperformed SPIR, delivering a return of -8.3% compared to -25.6%

GYRE vs SPIR - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	GYRE(COMPANY)	SPIR(COMPANY)
Market Cap	$543M	$545M
Max Drawdown	99.99%	97.74%
Sharpe Ratio	-0.37	0.91
5Y Beta	1.44	2.02
Industry	Biotechnology	Specialty Business Services
P/E Ratio	-147.91	10.57
Forward P/E	78.12	N/A
5Y EPS CAGR	-58.01%	N/A
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	0.57%	-20.10%
P/S Ratio	4.93	11.81
P/B Ratio	5.71	6.95

Market Cap

GYRE

$543M

Winner

SPIR

$545M

Max Drawdown

GYRE

99.99%

Winner

SPIR

97.74%

Sharpe Ratio

GYRE

-0.37

Winner

SPIR

0.91

5Y Beta

Winner

GYRE

1.44

SPIR

2.02

Industry

GYRE

Biotechnology

SPIR

Specialty Business Services

P/E Ratio

Winner

GYRE

-147.91

SPIR

10.57

Forward P/E

GYRE

78.12

SPIR

N/A

5Y EPS CAGR

GYRE

-58.01%

SPIR

N/A

Debt to Equity

GYRE

0.00%

SPIR

0.00%

Free Cash Flow Yield

Winner

GYRE

0.57%

SPIR

-20.10%

P/S Ratio

Winner

GYRE

4.93

SPIR

11.81

P/B Ratio

Winner

GYRE

5.71

SPIR

6.95

GYRE vs SPIR - Historical Returns

Returns include dividend reinvestment.

Period	GYRE	SPIR
1 month	-18.77%	+3.34%
3 months	-24.02%	+68.33%
6 months	-22.89%	+89.30%
1 year	-26.52%	+58.25%
5 years(CAGR)	-8.29%	-25.60%
10 years(CAGR)	-19.10%	N/A
Max(CAGR)	-23.02%	-22.78%

GYRE

-18.77%

Winner

SPIR

+3.34%

GYRE

-24.02%

Winner

SPIR

+68.33%

GYRE

-22.89%

Winner

SPIR

+89.30%

GYRE

-26.52%

Winner

SPIR

+58.25%

5Y(CAGR)

Winner

GYRE

-8.29%

SPIR

-25.60%

10Y(CAGR)

GYRE

-19.10%

SPIR

N/A

Max(CAGR)

GYRE

-23.02%

Winner

SPIR

-22.78%

GYRE vs SPIR - Annual Returns (2006 - 2026)

Returns include dividend reinvestment.

Year	GYRE	SPIR
2026	-12.92%	+133.42%
2025	-41.17%	-48.24%
2024	-49.14%	+81.78%
2023	+460.43%	-2.23%
2022	+103.46%	-72.49%
2021	-85.16%	-66.47%
2020	-2.92%	+3.20%
2019	-17.45%	N/A
2018	-45.09%	N/A
2017	+37.88%	N/A
2016	-78.82%	N/A
2015	-72.50%	N/A
2014	-36.78%	N/A
2013	-11.13%	N/A
2012	-22.06%	N/A
2011	-79.22%	N/A
2010	+29.33%	N/A
2009	+472.60%	N/A
2008	-56.74%	N/A
2007	-10.22%	N/A
2006	+4.50%	N/A

GYRE vs SPIR Drawdown Comparison

The maximum drawdown for GYRE was -99.98%, occurring on May 13, 2022. This drawdown has not yet recovered.

The maximum drawdown for SPIR was -97.74%, occurring on Jun 26, 2023. This drawdown has not yet recovered.

The current GYRE drawdown is -99.85%. The current SPIR drawdown is -87.65%.

Rank	GYRE	SPIR
#1	-99.98% Mar 3, 2011 - May 13, 2022	-97.74% Sep 22, 2021 - Jun 26, 2023
#2	-84.89% Jul 27, 2007 - Jul 28, 2009	-24.02% Mar 1, 2021 - Sep 3, 2021
#3	-38.22% Apr 12, 2006 - Dec 27, 2006	-22.53% Sep 3, 2021 - Sep 17, 2021
#4	-25.89% May 3, 2010 - Oct 25, 2010	-5.54% Sep 17, 2021 - Sep 21, 2021
#5	-21.70% Dec 4, 2009 - Apr 28, 2010	-3.39% Feb 5, 2021 - Mar 1, 2021
#6	-20.27% Oct 16, 2009 - Nov 23, 2009	-3.32% Jan 19, 2021 - Feb 5, 2021
#7	-19.38% Oct 7, 2009 - Oct 16, 2009	-2.06% Nov 3, 2020 - Nov 10, 2020
#8	-15.74% Nov 4, 2010 - Dec 16, 2010	-1.86% Dec 28, 2020 - Jan 8, 2021
#9	-15.72% Feb 23, 2007 - Apr 24, 2007	-1.60% Dec 7, 2020 - Dec 14, 2020
#10	-13.66% Jul 29, 2009 - Aug 7, 2009	-0.48% Nov 23, 2020 - Nov 27, 2020
#11	-11.04% Sep 30, 2009 - Oct 7, 2009	-0.41% Nov 10, 2020 - Nov 23, 2020
#12	-11.02% May 22, 2007 - Jul 27, 2007	-0.40% Dec 15, 2020 - Dec 18, 2020
#13	-9.23% Jan 14, 2011 - Feb 28, 2011	-0.35% Dec 21, 2020 - Dec 28, 2020
#14	-7.93% Jan 3, 2007 - Feb 23, 2007	-0.29% Jan 11, 2021 - Jan 13, 2021
#15	-7.04% Dec 1, 2009 - Dec 4, 2009	-0.29% Jan 13, 2021 - Jan 15, 2021