GYRE vs MDXG

Comparison between Gyre Therapeutics Inc (GYRE, Company) and Mimedx Group Inc (MDXG, Company).

Both GYRE and MDXG are from the Healthcare sector.

5-Year PerformanceGYRE has outperformed MDXG, delivering a return of -8.3% compared to -20.1%

GYRE vs MDXG - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	GYRE(COMPANY)	MDXG(COMPANY)
Market Cap	$543M	$542M
Max Drawdown	99.99%	93.83%
Sharpe Ratio	-0.44	-1.20
5Y Beta	1.45	0.75
Industry	Biotechnology	Biotechnology
P/E Ratio	-147.91	17.52
Forward P/E	78.12	19.53
PEG Ratio	N/A	2.88
5Y EPS CAGR	-58.01%	N/A
Debt to Equity	0.00%	7.24%
Free Cash Flow Yield	0.57%	13.02%
P/S Ratio	4.93	1.42
P/B Ratio	5.71	2.27

Market Cap

Winner

GYRE

$543M

MDXG

$542M

Max Drawdown

GYRE

99.99%

Winner

MDXG

93.83%

Sharpe Ratio

Winner

GYRE

-0.44

MDXG

-1.20

5Y Beta

GYRE

1.45

Winner

MDXG

0.75

Industry

GYRE

Biotechnology

MDXG

Biotechnology

P/E Ratio

Winner

GYRE

-147.91

MDXG

17.52

Forward P/E

GYRE

78.12

Winner

MDXG

19.53

PEG Ratio

GYRE

N/A

MDXG

2.88

5Y EPS CAGR

GYRE

-58.01%

MDXG

N/A

Debt to Equity

Winner

GYRE

0.00%

MDXG

7.24%

Free Cash Flow Yield

GYRE

0.57%

Winner

MDXG

13.02%

P/S Ratio

GYRE

4.93

Winner

MDXG

1.42

P/B Ratio

GYRE

5.71

Winner

MDXG

2.27

GYRE vs MDXG - Historical Returns

Returns include dividend reinvestment.

Period	GYRE	MDXG
1 month	-18.77%	+1.69%
3 months	-24.02%	-17.81%
6 months	-22.89%	-50.14%
1 year	-26.52%	-41.18%
5 years(CAGR)	-8.29%	-20.06%
10 years(CAGR)	-19.10%	-7.43%
Max(CAGR)	-23.02%	+13.95%

GYRE

-18.77%

Winner

MDXG

+1.69%

GYRE

-24.02%

Winner

MDXG

-17.81%

Winner

GYRE

-22.89%

MDXG

-50.14%

Winner

GYRE

-26.52%

MDXG

-41.18%

5Y(CAGR)

Winner

GYRE

-8.29%

MDXG

-20.06%

10Y(CAGR)

GYRE

-19.10%

Winner

MDXG

-7.43%

Max(CAGR)

GYRE

-23.02%

Winner

MDXG

+13.95%

GYRE vs MDXG - Annual Returns (2006 - 2026)

Returns include dividend reinvestment.

Year	GYRE	MDXG
2026	-12.92%	-44.44%
2025	-41.17%	-27.05%
2024	-49.14%	+22.24%
2023	+460.43%	+195.29%
2022	+103.46%	-55.66%
2021	-85.16%	-34.06%
2020	-2.92%	+24.38%
2019	-17.45%	+311.96%
2018	-45.09%	-86.21%
2017	+37.88%	+43.95%
2016	-78.82%	-1.12%
2015	-72.50%	-3.80%
2014	-36.78%	+36.45%
2013	-11.13%	+121.27%
2012	-22.06%	+207.20%
2011	-79.22%	-16.30%
2010	+29.33%	+80.00%
2009	+472.60%	-83.41%
2008	-56.74%	+1325.79%
2007	-10.22%	+0.00%
2006	+4.50%	N/A

GYRE vs MDXG Drawdown Comparison

The maximum drawdown for GYRE was -99.98%, occurring on May 13, 2022. This drawdown has not yet recovered.

The maximum drawdown for MDXG was -93.83%, occurring on Mar 24, 2009. Recovery took 1279 trading sessions.

The current GYRE drawdown is -99.85%. The current MDXG drawdown is -79.96%.

Rank	GYRE	MDXG
#1	-99.98% Mar 3, 2011 - May 13, 2022	-93.83% Mar 31, 2008 - Apr 29, 2013
#2	-84.89% Jul 27, 2007 - Jul 28, 2009	-93.60% Jan 29, 2018 - Dec 7, 2018
#3	-38.22% Apr 12, 2006 - Dec 27, 2006	-48.65% Jul 17, 2015 - May 3, 2017
#4	-25.89% May 3, 2010 - Oct 25, 2010	-47.65% Jun 25, 2013 - Dec 12, 2013
#5	-21.70% Dec 4, 2009 - Apr 28, 2010	-41.76% Dec 31, 2013 - Oct 15, 2014
#6	-20.27% Oct 16, 2009 - Nov 23, 2009	-37.31% Aug 22, 2017 - Jan 29, 2018
#7	-19.38% Oct 7, 2009 - Oct 16, 2009	-32.01% Dec 19, 2014 - Jul 13, 2015
#8	-15.74% Nov 4, 2010 - Dec 16, 2010	-31.32% Feb 11, 2008 - Mar 27, 2008
#9	-15.72% Feb 23, 2007 - Apr 24, 2007	-12.87% May 16, 2017 - Jun 21, 2017
#10	-13.66% Jul 29, 2009 - Aug 7, 2009	-8.66% Jun 23, 2017 - Aug 14, 2017
#11	-11.04% Sep 30, 2009 - Oct 7, 2009	-7.32% May 22, 2013 - Jun 25, 2013
#12	-11.02% May 22, 2007 - Jul 27, 2007	-6.13% Dec 9, 2014 - Dec 18, 2014
#13	-9.23% Jan 14, 2011 - Feb 28, 2011	-6.07% Apr 30, 2013 - May 16, 2013
#14	-7.93% Jan 3, 2007 - Feb 23, 2007	-5.80% Oct 15, 2014 - Oct 22, 2014
#15	-7.04% Dec 1, 2009 - Dec 4, 2009	-4.84% Aug 16, 2017 - Aug 22, 2017

Correlation

Correlation between GYRE and MDXG is -0.57 which considered as a moderate negative correlation - the stocks show some tendency to move in opposite directions.

-0.57

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