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GPCR vs SPY

Comparison between Structure Therapeutics Inc (GPCR, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).

GPCR vs SPY - Performance Comparison

Key Characteristics

Financial metrics and valuation ratios

Market Cap / Net Assets
GPCR
$3.90B
Winner
SPY
$781B
Expense Ratio
GPCR
N/A
SPY
0.09%
Max Drawdown
GPCR
80.96%
Winner
SPY
56.47%
Sharpe Ratio
GPCR
1.21
Winner
SPY
1.34
5Y Beta
Winner
GPCR
0.86
SPY
1.00
Industry
GPCR
Biotechnology
SPY
N/A
P/E Ratio
Winner
GPCR
-19.91
SPY
28.84
Forward P/E
GPCR
N/A
SPY
21.59
PEG Ratio
GPCR
-1.93
SPY
N/A
5Y Dividends CAGR
GPCR
N/A
SPY
6.00%
5Y EPS CAGR
GPCR
N/A
SPY
25.26%
Debt to Equity
Winner
GPCR
0.00%
SPY
31.47%
Free Cash Flow Yield
GPCR
-4.08%
SPY
N/A
P/S Ratio
GPCR
N/A
SPY
3.85
P/B Ratio
Winner
GPCR
2.63
SPY
5.70

GPCR vs SPY - Historical Returns

Returns include dividend reinvestment.

1M
Winner
GPCR
+17.46%
SPY
-0.14%
3M
GPCR
-4.94%
Winner
SPY
+8.54%
6M
GPCR
-40.01%
Winner
SPY
+9.48%
1Y
Winner
GPCR
+158.51%
SPY
+21.66%
5Y(CAGR)
GPCR
N/A
SPY
+13.03%
10Y(CAGR)
GPCR
N/A
SPY
+15.12%
Max(CAGR)
Winner
GPCR
+21.34%
SPY
+8.52%

GPCR vs SPY - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

YearGPCRSPY
2026-25.73%+10.64%
2025+146.72%+18.00%
2024-32.85%+25.59%
2023+56.77%+26.72%
2022N/A-18.64%
2021N/A+30.52%
2020N/A+17.28%
2019N/A+31.09%
2018N/A-5.24%
2017N/A+20.78%
2016N/A+13.59%
2015N/A+1.31%
2014N/A+14.56%
2013N/A+29.00%
2012N/A+14.17%
2011N/A+0.85%
2010N/A+13.14%
2009N/A+22.67%
2008N/A-36.25%
2007N/A+5.32%
2006N/A+13.85%
2005N/A+5.32%
2004N/A+10.75%
2003N/A+24.18%
2002N/A-22.42%
2001N/A-10.13%
2000N/A-8.84%
1999N/A+8.61%

GPCR vs SPY Drawdown Comparison

The maximum drawdown for GPCR was -80.96%, occurring on Apr 8, 2025. Recovery took 551 trading sessions.

The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.

The current GPCR drawdown is -46.06%. The current SPY drawdown is -0.77%.

RankGPCRSPY
#1-80.96%
Oct 31, 2023 - Jan 13, 2026		-55.20%
Oct 9, 2007 - Aug 16, 2012
#2-61.74%
Jan 21, 2026 - May 19, 2026		-47.50%
Mar 24, 2000 - Oct 26, 2006
#3-36.32%
Jul 3, 2023 - Sep 29, 2023		-33.70%
Feb 19, 2020 - Aug 10, 2020
#4-20.11%
Mar 3, 2023 - May 23, 2023		-24.50%
Jan 3, 2022 - Dec 13, 2023
#5-17.31%
Feb 3, 2023 - Mar 3, 2023		-19.34%
Sep 20, 2018 - Apr 12, 2019
#6-13.79%
Jun 9, 2023 - Jun 26, 2023		-18.76%
Feb 19, 2025 - Jun 26, 2025
#7-7.41%
Oct 3, 2023 - Oct 10, 2023		-13.02%
Jul 20, 2015 - Apr 18, 2016
#8-2.91%
Jun 6, 2023 - Jun 8, 2023		-10.10%
Jan 26, 2018 - Aug 6, 2018
#9-2.61%
Oct 26, 2023 - Oct 31, 2023		-9.44%
Sep 2, 2020 - Nov 11, 2020
#10-1.67%
Oct 24, 2023 - Oct 26, 2023		-9.30%
Jan 19, 2000 - Mar 17, 2000
#11-1.62%
Oct 16, 2023 - Oct 19, 2023		-9.05%
Jul 19, 2007 - Oct 5, 2007
#12-1.18%
Jun 1, 2023 - Jun 6, 2023		-8.88%
Jan 27, 2026 - Apr 14, 2026
#13-1.03%
May 26, 2023 - Jun 1, 2023		-8.41%
Jul 16, 2024 - Sep 19, 2024
#14-0.52%
Oct 12, 2023 - Oct 16, 2023		-7.35%
Sep 14, 2012 - Jan 2, 2013
#15N/A-7.27%
Sep 18, 2014 - Oct 31, 2014

Correlation

Correlation between GPCR and SPY is 0.17 which considered as a very weak or no correlation - the stocks move independently of each other.

0.17
-101

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