GPCR vs SPY
Comparison between Structure Therapeutics Inc (GPCR, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).
GPCR vs SPY - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap / Net Assets
GPCR
$2.81B
Winner
SPY
$735B
Expense Ratio
GPCR
N/A
SPY
0.09%
Max Drawdown
GPCR
80.96%
Winner
SPY
56.47%
Sharpe Ratio
GPCR
0.79
Winner
SPY
2.02
5Y Beta
Winner
GPCR
0.90
SPY
1.00
Industry
GPCR
Biotechnology
SPY
N/A
P/E Ratio
Winner
GPCR
-14.34
SPY
28.62
Forward P/E
GPCR
N/A
SPY
22.20
PEG Ratio
GPCR
-1.39
SPY
N/A
5Y Dividends CAGR
GPCR
N/A
SPY
5.43%
5Y EPS CAGR
GPCR
N/A
SPY
26.35%
Debt to Equity
Winner
GPCR
0.00%
SPY
33.33%
Free Cash Flow Yield
GPCR
-5.67%
SPY
N/A
P/S Ratio
GPCR
N/A
SPY
3.68
P/B Ratio
GPCR
N/A
SPY
5.52
GPCR vs SPY - Historical Returns
Returns include dividend reinvestment.
1M
GPCR
-12.77%
Winner
SPY
+4.93%
3M
GPCR
-37.22%
Winner
SPY
+9.70%
6M
Winner
GPCR
+15.55%
SPY
+11.04%
1Y
Winner
GPCR
+65.72%
SPY
+28.41%
5Y(CAGR)
GPCR
N/A
SPY
+13.90%
10Y(CAGR)
GPCR
N/A
SPY
+15.45%
Max(CAGR)
Winner
GPCR
+13.50%
SPY
+8.55%
GPCR vs SPY - Annual Returns (1999 - 2026)
Returns include dividend reinvestment.
| Year | GPCR | SPY |
|---|---|---|
| 2026 | -41.96% | +10.15% |
| 2025 | +146.72% | +18.00% |
| 2024 | -32.85% | +25.59% |
| 2023 | +56.77% | +26.72% |
| 2022 | N/A | -18.64% |
| 2021 | N/A | +30.52% |
| 2020 | N/A | +17.28% |
| 2019 | N/A | +31.09% |
| 2018 | N/A | -5.24% |
| 2017 | N/A | +20.78% |
| 2016 | N/A | +13.59% |
| 2015 | N/A | +1.31% |
| 2014 | N/A | +14.56% |
| 2013 | N/A | +29.00% |
| 2012 | N/A | +14.17% |
| 2011 | N/A | +0.85% |
| 2010 | N/A | +13.14% |
| 2009 | N/A | +22.67% |
| 2008 | N/A | -36.25% |
| 2007 | N/A | +5.32% |
| 2006 | N/A | +13.85% |
| 2005 | N/A | +5.32% |
| 2004 | N/A | +10.75% |
| 2003 | N/A | +24.18% |
| 2002 | N/A | -22.42% |
| 2001 | N/A | -10.13% |
| 2000 | N/A | -8.84% |
| 1999 | N/A | +8.61% |
GPCR vs SPY Drawdown Comparison
The maximum drawdown for GPCR was -80.96%, occurring on Apr 8, 2025. Recovery took 551 trading sessions.
The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.
The current GPCR drawdown is -57.84%. The current SPY drawdown is -0.02%.
| Rank | GPCR | SPY |
|---|---|---|
| #1 | -80.96% Oct 31, 2023 - Jan 13, 2026 | -55.20% Oct 9, 2007 - Aug 16, 2012 |
| #2 | -61.74% Jan 21, 2026 - May 19, 2026 | -47.50% Mar 24, 2000 - Oct 26, 2006 |
| #3 | -36.32% Jul 3, 2023 - Sep 29, 2023 | -33.70% Feb 19, 2020 - Aug 10, 2020 |
| #4 | -20.11% Mar 3, 2023 - May 23, 2023 | -24.50% Jan 3, 2022 - Dec 13, 2023 |
| #5 | -17.31% Feb 3, 2023 - Mar 3, 2023 | -19.34% Sep 20, 2018 - Apr 12, 2019 |
| #6 | -13.79% Jun 9, 2023 - Jun 26, 2023 | -18.76% Feb 19, 2025 - Jun 26, 2025 |
| #7 | -7.41% Oct 3, 2023 - Oct 10, 2023 | -13.02% Jul 20, 2015 - Apr 18, 2016 |
| #8 | -2.91% Jun 6, 2023 - Jun 8, 2023 | -10.10% Jan 26, 2018 - Aug 6, 2018 |
| #9 | -2.61% Oct 26, 2023 - Oct 31, 2023 | -9.44% Sep 2, 2020 - Nov 11, 2020 |
| #10 | -1.67% Oct 24, 2023 - Oct 26, 2023 | -9.30% Jan 19, 2000 - Mar 17, 2000 |
| #11 | -1.62% Oct 16, 2023 - Oct 19, 2023 | -9.05% Jul 19, 2007 - Oct 5, 2007 |
| #12 | -1.18% Jun 1, 2023 - Jun 6, 2023 | -8.88% Jan 27, 2026 - Apr 14, 2026 |
| #13 | -1.03% May 26, 2023 - Jun 1, 2023 | -8.41% Jul 16, 2024 - Sep 19, 2024 |
| #14 | -0.52% Oct 12, 2023 - Oct 16, 2023 | -7.35% Sep 14, 2012 - Jan 2, 2013 |
| #15 | N/A | -7.27% Sep 18, 2014 - Oct 31, 2014 |
Correlation
Correlation between GPCR and SPY is 0.10 which considered as a very weak or no correlation - the stocks move independently of each other.
0.10
-101
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