GLTO vs TLPH

Comparison between Galecto Inc (GLTO, Company) and Talphera Inc (TLPH, Company).

Both GLTO and TLPH are from the Healthcare sector.

5-Year PerformanceGLTO has outperformed TLPH, delivering a return of -29.7% compared to -48.1%

GLTO vs TLPH - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	GLTO(COMPANY)	TLPH(COMPANY)
Market Cap	$53M	$53M
Max Drawdown	99.47%	99.85%
Sharpe Ratio	1.30	1.33
5Y Beta	N/A	0.72
Industry	Biotechnology	Drug Manufacturers - Specialty & Generic
P/E Ratio	-0.15	-2.68
Forward P/E	N/A	1.02
PEG Ratio	-0.00	N/A
5Y EPS CAGR	N/A	-41.25%
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	-46.89%	-21.29%

Market Cap

Winner

GLTO

$53M

TLPH

$53M

Max Drawdown

Winner

GLTO

99.47%

TLPH

99.85%

Sharpe Ratio

GLTO

1.30

Winner

TLPH

1.33

5Y Beta

GLTO

N/A

TLPH

0.72

Industry

GLTO

Biotechnology

TLPH

Drug Manufacturers - Specialty & Generic

P/E Ratio

GLTO

-0.15

Winner

TLPH

-2.68

Forward P/E

GLTO

N/A

TLPH

1.02

PEG Ratio

GLTO

-0.00

TLPH

N/A

5Y EPS CAGR

GLTO

N/A

TLPH

-41.25%

Debt to Equity

GLTO

0.00%

TLPH

0.00%

Free Cash Flow Yield

GLTO

-46.89%

Winner

TLPH

-21.29%

GLTO vs TLPH - Historical Returns

Returns include dividend reinvestment.

Period	GLTO	TLPH
1 month	-12.82%	+33.75%
3 months	-9.90%	+34.35%
6 months	-23.47%	-5.31%
1 year	+558.02%	+139.37%
5 years(CAGR)	-29.68%	-48.10%
10 years(CAGR)	N/A	-32.10%
Max(CAGR)	-39.17%	-25.11%

GLTO

-12.82%

Winner

TLPH

+33.75%

GLTO

-9.90%

Winner

TLPH

+34.35%

GLTO

-23.47%

Winner

TLPH

-5.31%

Winner

GLTO

+558.02%

TLPH

+139.37%

5Y(CAGR)

Winner

GLTO

-29.68%

TLPH

-48.10%

10Y(CAGR)

GLTO

N/A

TLPH

-32.10%

Max(CAGR)

GLTO

-39.17%

Winner

TLPH

-25.11%

GLTO vs TLPH - Annual Returns (2011 - 2026)

Returns include dividend reinvestment.

Year	GLTO	TLPH
2026	+3.44%	-7.76%
2025	+303.68%	+93.19%
2024	-73.97%	-29.21%
2023	-40.50%	-66.89%
2022	-64.51%	-81.32%
2021	-76.69%	-55.18%
2020	-16.60%	-40.10%
2019	N/A	-14.92%
2018	N/A	+12.68%
2017	N/A	-20.39%
2016	N/A	-31.49%
2015	N/A	-43.47%
2014	N/A	-42.33%
2013	N/A	+146.41%
2012	N/A	+120.73%
2011	N/A	-57.80%

GLTO vs TLPH Drawdown Comparison

The maximum drawdown for GLTO was -99.47%, occurring on Apr 10, 2025. This drawdown has not yet recovered.

The maximum drawdown for TLPH was -99.85%, occurring on Aug 7, 2025. This drawdown has not yet recovered.

The current GLTO drawdown is -94.64%. The current TLPH drawdown is -99.59%.

Rank	GLTO	TLPH
#1	-99.47% Nov 23, 2020 - Apr 10, 2025	-99.85% Jul 22, 2013 - Aug 7, 2025
#2	-4.74% Nov 16, 2020 - Nov 23, 2020	-60.00% May 31, 2011 - Nov 26, 2012
#3	-2.99% Nov 3, 2020 - Nov 6, 2020	-33.63% Feb 11, 2011 - May 27, 2011
#4	-0.46% Nov 6, 2020 - Nov 11, 2020	-33.40% Nov 26, 2012 - Jan 18, 2013
#5	N/A	-21.97% Feb 13, 2013 - Apr 11, 2013
#6	N/A	-15.90% Jun 11, 2013 - Jul 2, 2013
#7	N/A	-10.99% May 16, 2013 - May 22, 2013
#8	N/A	-9.84% Jan 22, 2013 - Feb 13, 2013
#9	N/A	-9.76% Apr 23, 2013 - May 7, 2013
#10	N/A	-9.29% Apr 12, 2013 - Apr 23, 2013
#11	N/A	-8.49% May 30, 2013 - Jun 10, 2013
#12	N/A	-6.94% May 7, 2013 - May 14, 2013
#13	N/A	-6.36% Jul 11, 2013 - Jul 22, 2013
#14	N/A	-4.27% Jul 2, 2013 - Jul 8, 2013
#15	N/A	-3.34% Jul 8, 2013 - Jul 10, 2013