DVAX vs TYRA

Comparison between Dynavax Technologies Corp (DVAX, Company) and Tyra Biosciences Inc (TYRA, Company).

Both DVAX and TYRA are from the Healthcare sector.

5-Year PerformanceDVAX has outperformed TYRA, delivering a return of +10.2% compared to +3.6%

DVAX vs TYRA - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	DVAX(COMPANY)	TYRA(COMPANY)
Market Cap	$1.82B	$1.82B
Max Drawdown	98.47%	83.22%
Sharpe Ratio	0.47	2.01
5Y Beta	N/A	1.01
Industry	Drug Manufacturers - Specialty & Generic	Biotechnology
P/E Ratio	-46.75	-12.86
Forward P/E	29.24	N/A
PEG Ratio	N/A	-0.44
5Y EPS CAGR	-20.02%	N/A
Debt to Equity	0.00%	0.00%
Free Cash Flow Yield	4.43%	-5.63%
P/B Ratio	N/A	4.88

Market Cap

DVAX

$1.82B

Winner

TYRA

$1.82B

Max Drawdown

DVAX

98.47%

Winner

TYRA

83.22%

Sharpe Ratio

DVAX

0.47

Winner

TYRA

2.01

5Y Beta

DVAX

N/A

TYRA

1.01

Industry

DVAX

Drug Manufacturers - Specialty & Generic

TYRA

Biotechnology

P/E Ratio

Winner

DVAX

-46.75

TYRA

-12.86

Forward P/E

DVAX

29.24

TYRA

N/A

PEG Ratio

DVAX

N/A

TYRA

-0.44

5Y EPS CAGR

DVAX

-20.02%

TYRA

N/A

Debt to Equity

DVAX

0.00%

TYRA

0.00%

Free Cash Flow Yield

Winner

DVAX

4.43%

TYRA

-5.63%

P/B Ratio

DVAX

N/A

TYRA

4.88

DVAX vs TYRA - Historical Returns

Returns include dividend reinvestment.

Period	DVAX	TYRA
1 month	-1.15%	+2.46%
3 months	+37.53%	-16.05%
6 months	+47.97%	+1.42%
1 year	+22.05%	+184.92%
5 years(CAGR)	+10.22%	+3.55%
10 years(CAGR)	-1.97%	N/A
Max(CAGR)	-7.87%	+3.55%

DVAX

-1.15%

Winner

TYRA

+2.46%

Winner

DVAX

+37.53%

TYRA

-16.05%

Winner

DVAX

+47.97%

TYRA

+1.42%

DVAX

+22.05%

Winner

TYRA

+184.92%

5Y(CAGR)

Winner

DVAX

+10.22%

TYRA

+3.55%

10Y(CAGR)

DVAX

-1.97%

TYRA

N/A

Max(CAGR)

DVAX

-7.87%

Winner

TYRA

+3.55%

DVAX vs TYRA - Annual Returns (2004 - 2026)

Returns include dividend reinvestment.

Year	DVAX	TYRA
2026	+0.78%	+14.97%
2025	+19.22%	+82.19%
2024	-11.20%	-1.00%
2023	+31.89%	+95.90%
2022	-23.34%	-46.06%
2021	+204.55%	-45.88%
2020	-18.65%	N/A
2019	-39.47%	N/A
2018	-51.33%	N/A
2017	+361.73%	N/A
2016	-82.94%	N/A
2015	+38.77%	N/A
2014	-15.28%	N/A
2013	-32.88%	N/A
2012	-13.11%	N/A
2011	+7.44%	N/A
2010	+122.22%	N/A
2009	+79.77%	N/A
2008	-84.00%	N/A
2007	-39.67%	N/A
2006	+113.99%	N/A
2005	-45.96%	N/A
2004	-14.89%	N/A

DVAX vs TYRA Drawdown Comparison

The maximum drawdown for DVAX was -98.47%, occurring on Nov 20, 2008. This drawdown has not yet recovered.

The maximum drawdown for TYRA was -83.22%, occurring on Jun 17, 2022. Recovery took 1058 trading sessions.

The current DVAX drawdown is -84.26%. The current TYRA drawdown is -22.24%.

Rank	DVAX	TYRA
#1	-98.47% Dec 11, 2006 - Nov 20, 2008	-83.22% Nov 4, 2021 - Jan 27, 2026
#2	-61.81% Feb 19, 2004 - Nov 29, 2006	-48.23% Sep 15, 2021 - Nov 3, 2021
#3	-7.25% Nov 29, 2006 - Dec 11, 2006	-35.82% Apr 2, 2026 - Jun 10, 2026
#4	N/A	-13.45% Jan 29, 2026 - Feb 23, 2026
#5	N/A	-9.38% Mar 19, 2026 - Mar 31, 2026
#6	N/A	-5.74% Feb 25, 2026 - Mar 4, 2026
#7	N/A	-4.31% Mar 4, 2026 - Mar 11, 2026
#8	N/A	-1.48% Mar 11, 2026 - Mar 16, 2026
#9	N/A	-1.02% Jan 27, 2026 - Jan 29, 2026
#10	N/A	-0.05% Mar 31, 2026 - Apr 2, 2026