DNLI vs SYNA

Comparison between Denali Therapeutics Inc (DNLI, Company) and Synaptics Inc (SYNA, Company).

DNLI is from the Healthcare sector, while SYNA is from the Technology sector.

5-Year PerformanceSYNA has outperformed DNLI, delivering a return of -8.3% compared to -13.7%

DNLI vs SYNA - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	DNLI(COMPANY)	SYNA(COMPANY)
Market Cap	$3.87B	$3.88B
Max Drawdown	87.74%	85.34%
Sharpe Ratio	1.26	1.14
5Y Beta	1.47	2.09
Industry	Biotechnology	Semiconductors
P/E Ratio	-7.29	-80.91
Forward P/E	N/A	19.57
PEG Ratio	-1.14	0.51
Debt to Equity	0.00%	61.58%
Free Cash Flow Yield	-10.89%	2.49%
P/S Ratio	3643.65	3.34
P/B Ratio	3.94	3.07

Market Cap

DNLI

$3.87B

Winner

SYNA

$3.88B

Max Drawdown

DNLI

87.74%

Winner

SYNA

85.34%

Sharpe Ratio

Winner

DNLI

1.26

SYNA

1.14

5Y Beta

Winner

DNLI

1.47

SYNA

2.09

Industry

DNLI

Biotechnology

SYNA

Semiconductors

P/E Ratio

DNLI

-7.29

Winner

SYNA

-80.91

Forward P/E

DNLI

N/A

SYNA

19.57

PEG Ratio

Winner

DNLI

-1.14

SYNA

0.51

Debt to Equity

Winner

DNLI

0.00%

SYNA

61.58%

Free Cash Flow Yield

DNLI

-10.89%

Winner

SYNA

2.49%

P/S Ratio

DNLI

3643.65

Winner

SYNA

3.34

P/B Ratio

DNLI

3.94

Winner

SYNA

3.07

DNLI vs SYNA - Historical Returns

Returns include dividend reinvestment.

Period	DNLI	SYNA
1 month	-4.57%	-7.65%
3 months	+29.86%	-7.99%
6 months	+31.75%	+19.52%
1 year	+91.15%	+63.05%
5 years(CAGR)	-13.75%	-8.26%
10 years(CAGR)	+1.91%	+7.10%
Max(CAGR)	+1.91%	+10.88%

Winner

DNLI

-4.57%

SYNA

-7.65%

Winner

DNLI

+29.86%

SYNA

-7.99%

Winner

DNLI

+31.75%

SYNA

+19.52%

Winner

DNLI

+91.15%

SYNA

+63.05%

5Y(CAGR)

DNLI

-13.75%

Winner

SYNA

-8.26%

10Y(CAGR)

DNLI

+1.91%

Winner

SYNA

+7.10%

Max(CAGR)

DNLI

+1.91%

Winner

SYNA

+10.88%

DNLI vs SYNA - Annual Returns (2002 - 2026)

Returns include dividend reinvestment.

Year	DNLI	SYNA
2026	+55.32%	+45.29%
2025	-20.78%	-10.26%
2024	-4.72%	-31.24%
2023	-22.33%	+23.22%
2022	-41.17%	-67.02%
2021	-37.06%	+197.24%
2020	+411.04%	+45.49%
2019	-9.88%	+75.20%
2018	+28.08%	-9.57%
2017	-27.09%	-28.44%
2016	N/A	-31.18%
2015	N/A	+25.04%
2014	N/A	+36.78%
2013	N/A	+70.26%
2012	N/A	-1.06%
2011	N/A	-1.86%
2010	N/A	-9.15%
2009	N/A	+80.40%
2008	N/A	-42.53%
2007	N/A	+37.52%
2006	N/A	+18.29%
2005	N/A	-16.09%
2004	N/A	+94.16%
2003	N/A	+93.54%
2002	N/A	-42.03%

DNLI vs SYNA Drawdown Comparison

The maximum drawdown for DNLI was -87.74%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The maximum drawdown for SYNA was -85.34%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The current DNLI drawdown is -72.99%. The current SYNA drawdown is -62.42%.

Rank	DNLI	SYNA
#1	-87.74% Dec 22, 2020 - Apr 8, 2025	-85.34% Dec 7, 2021 - Apr 8, 2025
#2	-49.76% Feb 16, 2018 - Apr 2, 2019	-81.70% Apr 17, 2002 - Jan 26, 2004
#3	-49.54% Apr 10, 2019 - Jun 2, 2020	-73.94% Jun 18, 2015 - Jan 7, 2021
#4	-29.88% Dec 8, 2017 - Jan 22, 2018	-64.43% Nov 6, 2007 - Jun 10, 2009
#5	-19.74% Jun 3, 2020 - Aug 6, 2020	-61.93% Feb 4, 2005 - Aug 8, 2007
#6	-19.58% Jan 29, 2018 - Feb 16, 2018	-48.32% Jun 10, 2009 - Mar 28, 2013
#7	-13.33% Nov 12, 2020 - Dec 4, 2020	-39.24% Jan 26, 2004 - Oct 4, 2004
#8	-11.16% Aug 10, 2020 - Aug 25, 2020	-36.94% Jul 3, 2014 - May 18, 2015
#9	-10.43% Sep 17, 2020 - Oct 7, 2020	-31.27% Nov 24, 2004 - Feb 4, 2005
#10	-10.33% Oct 13, 2020 - Oct 27, 2020	-20.80% May 14, 2013 - Sep 25, 2013
#11	-9.64% Aug 25, 2020 - Sep 14, 2020	-19.19% Oct 17, 2013 - Jan 14, 2014
#12	-7.28% Oct 28, 2020 - Nov 4, 2020	-19.07% Apr 27, 2021 - Jun 14, 2021
#13	-3.20% Jan 23, 2018 - Jan 26, 2018	-16.39% Feb 15, 2002 - Mar 6, 2002
#14	-2.37% Apr 3, 2019 - Apr 5, 2019	-15.63% Feb 26, 2014 - Apr 23, 2014
#15	-1.33% Dec 16, 2020 - Dec 18, 2020	-15.06% Apr 23, 2014 - May 28, 2014