DNLI vs SKYW

Comparison between Denali Therapeutics Inc (DNLI, Company) and Skywest Inc (SKYW, Company).

DNLI is from the Healthcare sector, while SKYW is from the Industrials sector.

5-Year PerformanceSKYW has outperformed DNLI, delivering a return of +15.3% compared to -20.6%

DNLI vs SKYW - Performance Comparison

Log

Key Characteristics

Financial metrics and valuation ratios

Metric	DNLI(COMPANY)	SKYW(COMPANY)
Market Cap	$3.70B	$3.71B
Max Drawdown	87.74%	81.77%
Sharpe Ratio	1.11	-0.03
5Y Beta	1.51	1.34
Industry	Biotechnology	Airlines
P/E Ratio	-6.96	8.51
Forward P/E	N/A	9.52
PEG Ratio	-1.09	0.11
5Y Dividends CAGR	N/A	25.59%
5Y EPS CAGR	N/A	10.91%
Debt to Equity	0.00%	87.62%
Free Cash Flow Yield	-11.41%	23.65%

Market Cap

DNLI

$3.70B

Winner

SKYW

$3.71B

Max Drawdown

DNLI

87.74%

Winner

SKYW

81.77%

Sharpe Ratio

Winner

DNLI

1.11

SKYW

-0.03

5Y Beta

DNLI

1.51

Winner

SKYW

1.34

Industry

DNLI

Biotechnology

SKYW

Airlines

P/E Ratio

Winner

DNLI

-6.96

SKYW

8.51

Forward P/E

DNLI

N/A

SKYW

9.52

PEG Ratio

Winner

DNLI

-1.09

SKYW

0.11

5Y Dividends CAGR

DNLI

N/A

SKYW

25.59%

5Y EPS CAGR

DNLI

N/A

SKYW

10.91%

Debt to Equity

Winner

DNLI

0.00%

SKYW

87.62%

Free Cash Flow Yield

DNLI

-11.41%

Winner

SKYW

23.65%

DNLI vs SKYW - Historical Returns

Returns include dividend reinvestment.

Period	DNLI	SKYW
1 month	+26.68%	+13.25%
3 months	+16.20%	+4.13%
6 months	+39.00%	-11.17%
1 year	+65.44%	-4.38%
5 years(CAGR)	-20.57%	+15.25%
10 years(CAGR)	+0.98%	+14.49%
Max(CAGR)	+0.98%	+8.48%

Winner

DNLI

+26.68%

SKYW

+13.25%

Winner

DNLI

+16.20%

SKYW

+4.13%

Winner

DNLI

+39.00%

SKYW

-11.17%

Winner

DNLI

+65.44%

SKYW

-4.38%

5Y(CAGR)

DNLI

-20.57%

Winner

SKYW

+15.25%

10Y(CAGR)

DNLI

+0.98%

Winner

SKYW

+14.49%

Max(CAGR)

DNLI

+0.98%

Winner

SKYW

+8.48%

DNLI vs SKYW - Annual Returns (1999 - 2026)

Returns include dividend reinvestment.

Year	DNLI	SKYW
2026	+43.27%	-8.47%
2025	-20.78%	-0.66%
2024	-4.72%	+93.71%
2023	-22.33%	+217.71%
2022	-41.17%	-59.30%
2021	-37.06%	+3.58%
2020	+411.04%	-37.69%
2019	-9.88%	+43.48%
2018	+28.08%	-15.44%
2017	-27.09%	+46.44%
2016	N/A	+104.81%
2015	N/A	+45.05%
2014	N/A	-8.89%
2013	N/A	+17.98%
2012	N/A	-1.74%
2011	N/A	-20.19%
2010	N/A	-6.53%
2009	N/A	-10.15%
2008	N/A	-29.63%
2007	N/A	+4.03%
2006	N/A	-3.75%
2005	N/A	+33.04%
2004	N/A	+12.85%
2003	N/A	+36.27%
2002	N/A	-46.29%
2001	N/A	-7.10%
2000	N/A	+101.37%
1999	N/A	+11.50%

DNLI vs SKYW Drawdown Comparison

The maximum drawdown for DNLI was -87.74%, occurring on Apr 8, 2025. This drawdown has not yet recovered.

The maximum drawdown for SKYW was -81.77%, occurring on Mar 18, 2020. Recovery took 1038 trading sessions.

The current DNLI drawdown is -75.09%. The current SKYW drawdown is -25.13%.

Rank	DNLI	SKYW
#1	-87.74% Dec 22, 2020 - Apr 8, 2025	-81.77% Jan 17, 2020 - Mar 5, 2024
#2	-49.76% Feb 16, 2018 - Apr 2, 2019	-79.75% Aug 1, 2001 - Sep 8, 2016
#3	-49.54% Apr 10, 2019 - Jun 2, 2020	-40.73% Dec 1, 2000 - May 25, 2001
#4	-29.88% Dec 8, 2017 - Jan 22, 2018	-36.63% Aug 26, 2025 - May 19, 2026
#5	-19.74% Jun 3, 2020 - Aug 6, 2020	-34.33% Jan 31, 2025 - Aug 25, 2025
#6	-19.58% Jan 29, 2018 - Feb 16, 2018	-34.22% Aug 31, 2018 - Dec 18, 2019
#7	-13.33% Nov 12, 2020 - Dec 4, 2020	-27.14% Apr 24, 2000 - Jul 13, 2000
#8	-11.16% Aug 10, 2020 - Aug 25, 2020	-23.16% Nov 8, 1999 - Dec 29, 1999
#9	-10.43% Sep 17, 2020 - Oct 7, 2020	-22.36% Dec 20, 2016 - Sep 13, 2017
#10	-10.33% Oct 13, 2020 - Oct 27, 2020	-22.30% Jul 16, 2024 - Oct 10, 2024
#11	-9.64% Aug 25, 2020 - Sep 14, 2020	-16.99% Jan 10, 2000 - Mar 16, 2000
#12	-7.28% Oct 28, 2020 - Nov 4, 2020	-15.87% May 25, 2001 - Jul 16, 2001
#13	-3.20% Jan 23, 2018 - Jan 26, 2018	-15.10% Mar 16, 2018 - Jul 27, 2018
#14	-2.37% Apr 3, 2019 - Apr 5, 2019	-14.84% Sep 8, 2016 - Oct 20, 2016
#15	-1.33% Dec 16, 2020 - Dec 18, 2020	-14.24% Sep 5, 2000 - Sep 27, 2000

Correlation

Correlation between DNLI and SKYW is -0.35 which considered as a weak negative correlation - the stocks show a slight tendency to move in opposite directions.

-0.35

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