CRSP vs SPY
Comparison between CRISPR Therapeutics AG (CRSP, Company) and SPDR S&P 500 ETF Trust (SPY, ETF).
5-Year PerformanceSPY has outperformed CRSP, delivering a return of +13.8% compared to -16.2%
CRSP vs SPY - Performance Comparison
Key Characteristics
Financial metrics and valuation ratios
Market Cap / Net Assets
CRSP
$4.68B
Winner
SPY
$735B
Expense Ratio
CRSP
N/A
SPY
0.09%
Max Drawdown
CRSP
85.11%
Winner
SPY
56.47%
Sharpe Ratio
CRSP
0.61
Winner
SPY
1.67
5Y Beta
CRSP
1.43
Winner
SPY
1.00
Industry
CRSP
Biotechnology
SPY
N/A
P/E Ratio
Winner
CRSP
-7.92
SPY
28.81
Forward P/E
CRSP
23.36
Winner
SPY
22.07
PEG Ratio
CRSP
-0.22
SPY
N/A
5Y Dividends CAGR
CRSP
N/A
SPY
5.43%
5Y EPS CAGR
CRSP
2.10%
Winner
SPY
25.84%
Debt to Equity
Winner
CRSP
32.27%
SPY
34.16%
Free Cash Flow Yield
CRSP
-8.57%
SPY
N/A
P/S Ratio
CRSP
N/A
SPY
3.69
P/B Ratio
CRSP
N/A
SPY
5.54
CRSP vs SPY - Historical Returns
Returns include dividend reinvestment.
1M
CRSP
-15.84%
Winner
SPY
+4.59%
3M
CRSP
-9.18%
Winner
SPY
+7.81%
6M
CRSP
-1.50%
Winner
SPY
+14.24%
1Y
CRSP
+23.69%
Winner
SPY
+26.47%
5Y(CAGR)
CRSP
-16.23%
Winner
SPY
+13.84%
10Y(CAGR)
CRSP
+13.78%
Winner
SPY
+15.57%
Max(CAGR)
Winner
CRSP
+13.78%
SPY
+8.50%
CRSP vs SPY - Annual Returns (1999 - 2026)
Returns include dividend reinvestment.
| Year | CRSP | SPY |
|---|---|---|
| 2026 | -9.71% | +8.80% |
| 2025 | +26.57% | +18.00% |
| 2024 | -40.42% | +25.59% |
| 2023 | +52.68% | +26.72% |
| 2022 | -48.70% | -18.64% |
| 2021 | -52.04% | +30.52% |
| 2020 | +158.11% | +17.28% |
| 2019 | +103.90% | +31.09% |
| 2018 | +13.51% | -5.24% |
| 2017 | +4.36% | +20.78% |
| 2016 | +43.79% | +13.59% |
| 2015 | N/A | +1.31% |
| 2014 | N/A | +14.56% |
| 2013 | N/A | +29.00% |
| 2012 | N/A | +14.17% |
| 2011 | N/A | +0.85% |
| 2010 | N/A | +13.14% |
| 2009 | N/A | +22.67% |
| 2008 | N/A | -36.25% |
| 2007 | N/A | +5.32% |
| 2006 | N/A | +13.85% |
| 2005 | N/A | +5.32% |
| 2004 | N/A | +10.75% |
| 2003 | N/A | +24.18% |
| 2002 | N/A | -22.42% |
| 2001 | N/A | -10.13% |
| 2000 | N/A | -8.84% |
| 1999 | N/A | +8.61% |
CRSP vs SPY Drawdown Comparison
The maximum drawdown for CRSP was -85.11%, occurring on Apr 8, 2025. This drawdown has not yet recovered.
The maximum drawdown for SPY was -55.20%, occurring on Mar 9, 2009. Recovery took 1224 trading sessions.
The current CRSP drawdown is -76.89%. The current SPY drawdown is -0.92%.
| Rank | CRSP | SPY |
|---|---|---|
| #1 | -85.11% Jan 14, 2021 - Apr 8, 2025 | -55.20% Oct 9, 2007 - Aug 16, 2012 |
| #2 | -69.11% May 30, 2018 - Jun 23, 2020 | -47.50% Mar 24, 2000 - Oct 26, 2006 |
| #3 | -42.60% Feb 28, 2017 - Jan 2, 2018 | -33.70% Feb 19, 2020 - Aug 10, 2020 |
| #4 | -37.24% Jan 4, 2017 - Feb 28, 2017 | -24.50% Jan 3, 2022 - Dec 13, 2023 |
| #5 | -26.73% Mar 14, 2018 - May 17, 2018 | -19.34% Sep 20, 2018 - Apr 12, 2019 |
| #6 | -21.55% Oct 16, 2020 - Nov 23, 2020 | -18.76% Feb 19, 2025 - Jun 26, 2025 |
| #7 | -21.42% Jan 29, 2018 - Feb 26, 2018 | -13.02% Jul 20, 2015 - Apr 18, 2016 |
| #8 | -20.84% Aug 19, 2020 - Oct 13, 2020 | -10.10% Jan 26, 2018 - Aug 6, 2018 |
| #9 | -17.51% Nov 29, 2016 - Jan 4, 2017 | -9.44% Sep 2, 2020 - Nov 11, 2020 |
| #10 | -16.71% Oct 31, 2016 - Nov 16, 2016 | -9.30% Jan 19, 2000 - Mar 17, 2000 |
| #11 | -11.61% Dec 23, 2020 - Jan 7, 2021 | -9.05% Jul 19, 2007 - Oct 5, 2007 |
| #12 | -11.28% Nov 17, 2016 - Nov 29, 2016 | -8.88% Jan 27, 2026 - Apr 14, 2026 |
| #13 | -10.33% Jul 20, 2020 - Aug 19, 2020 | -8.41% Jul 16, 2024 - Sep 19, 2024 |
| #14 | -8.43% Jul 8, 2020 - Jul 20, 2020 | -7.35% Sep 14, 2012 - Jan 2, 2013 |
| #15 | -6.56% Jan 2, 2018 - Jan 5, 2018 | -7.27% Sep 18, 2014 - Oct 31, 2014 |
Correlation
Correlation between CRSP and SPY is 0.18 which considered as a very weak or no correlation - the stocks move independently of each other.
0.18
-101
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